JPH0535138B2 - - Google Patents
Info
- Publication number
- JPH0535138B2 JPH0535138B2 JP726087A JP726087A JPH0535138B2 JP H0535138 B2 JPH0535138 B2 JP H0535138B2 JP 726087 A JP726087 A JP 726087A JP 726087 A JP726087 A JP 726087A JP H0535138 B2 JPH0535138 B2 JP H0535138B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- amino
- optically active
- azide derivative
- hydroxybutyric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001540 azides Chemical class 0.000 claims description 9
- 230000003287 optical effect Effects 0.000 claims description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 125000004429 atom Chemical group 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
- -1 t-butoxycarbonyl group Chemical group 0.000 claims description 2
- 238000000034 method Methods 0.000 description 11
- 239000007858 starting material Substances 0.000 description 5
- YQGDEPYYFWUPGO-UHFFFAOYSA-N gamma-amino-beta-hydroxybutyric acid Chemical compound [NH3+]CC(O)CC([O-])=O YQGDEPYYFWUPGO-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- YQGDEPYYFWUPGO-GSVOUGTGSA-N (3r)-4-amino-3-hydroxybutanoic acid Chemical compound NC[C@H](O)CC(O)=O YQGDEPYYFWUPGO-GSVOUGTGSA-N 0.000 description 2
- ASNHGEVAWNWCRQ-UHFFFAOYSA-N 4-(hydroxymethyl)oxolane-2,3,4-triol Chemical compound OCC1(O)COC(O)C1O ASNHGEVAWNWCRQ-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 239000002243 precursor Substances 0.000 description 2
- BRLQWZUYTZBJKN-VKHMYHEASA-N (-)-Epichlorohydrin Chemical compound ClC[C@H]1CO1 BRLQWZUYTZBJKN-VKHMYHEASA-N 0.000 description 1
- BAPRUDZDYCKSOQ-RITPCOANSA-N (2s,4r)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid Chemical compound CC(=O)N1C[C@H](O)C[C@H]1C(O)=O BAPRUDZDYCKSOQ-RITPCOANSA-N 0.000 description 1
- ZVNYKZKUBKIIAH-UHFFFAOYSA-N 2-(oxiran-2-yl)acetic acid Chemical compound OC(=O)CC1CO1 ZVNYKZKUBKIIAH-UHFFFAOYSA-N 0.000 description 1
- VSLPYOQEAHSTCW-UHFFFAOYSA-N 2-amino-3-hydroxybutanenitrile Chemical compound CC(O)C(N)C#N VSLPYOQEAHSTCW-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- TVHCXXXXQNWQLP-UHFFFAOYSA-N Dl-threonine methyl ester Chemical compound COC(=O)C(N)C(C)O TVHCXXXXQNWQLP-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
- 239000002211 L-ascorbic acid Substances 0.000 description 1
- 235000000069 L-ascorbic acid Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 150000004648 butanoic acid derivatives Chemical class 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP726087A JPS63174959A (ja) | 1987-01-13 | 1987-01-13 | アジド誘導体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP726087A JPS63174959A (ja) | 1987-01-13 | 1987-01-13 | アジド誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63174959A JPS63174959A (ja) | 1988-07-19 |
| JPH0535138B2 true JPH0535138B2 (enrdf_load_stackoverflow) | 1993-05-25 |
Family
ID=11661056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP726087A Granted JPS63174959A (ja) | 1987-01-13 | 1987-01-13 | アジド誘導体 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63174959A (enrdf_load_stackoverflow) |
-
1987
- 1987-01-13 JP JP726087A patent/JPS63174959A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63174959A (ja) | 1988-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |