JPH0480038B2 - - Google Patents

Info

Publication number
JPH0480038B2
JPH0480038B2 JP1211208A JP21120889A JPH0480038B2 JP H0480038 B2 JPH0480038 B2 JP H0480038B2 JP 1211208 A JP1211208 A JP 1211208A JP 21120889 A JP21120889 A JP 21120889A JP H0480038 B2 JPH0480038 B2 JP H0480038B2
Authority
JP
Japan
Prior art keywords
dione
fluoro
ene
fluoroandrost
hydroxyandrost
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP1211208A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0276896A (ja
Inventor
Maikeru Teimuko Josefu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of JPH0276896A publication Critical patent/JPH0276896A/ja
Publication of JPH0480038B2 publication Critical patent/JPH0480038B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP1211208A 1981-07-24 1989-08-15 ステロイド化合物およびその製造方法 Granted JPH0276896A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/286,306 US4383947A (en) 1981-07-24 1981-07-24 Introduction of a fluorine atom
US286306 1981-07-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP57124289A Division JPS5824595A (ja) 1981-07-24 1982-07-16 ステロイド化合物およびその製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3257524A Division JPH0689021B2 (ja) 1981-07-24 1991-10-04 ステロイド化合物

Publications (2)

Publication Number Publication Date
JPH0276896A JPH0276896A (ja) 1990-03-16
JPH0480038B2 true JPH0480038B2 (d) 1992-12-17

Family

ID=23097997

Family Applications (3)

Application Number Title Priority Date Filing Date
JP57124289A Granted JPS5824595A (ja) 1981-07-24 1982-07-16 ステロイド化合物およびその製造方法
JP1211208A Granted JPH0276896A (ja) 1981-07-24 1989-08-15 ステロイド化合物およびその製造方法
JP3257524A Expired - Lifetime JPH0689021B2 (ja) 1981-07-24 1991-10-04 ステロイド化合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP57124289A Granted JPS5824595A (ja) 1981-07-24 1982-07-16 ステロイド化合物およびその製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3257524A Expired - Lifetime JPH0689021B2 (ja) 1981-07-24 1991-10-04 ステロイド化合物

Country Status (8)

Country Link
US (1) US4383947A (d)
JP (3) JPS5824595A (d)
CH (1) CH651053A5 (d)
DE (1) DE3226164A1 (d)
FR (1) FR2530641B1 (d)
GB (2) GB2102805B (d)
IT (1) IT1157224B (d)
NL (1) NL8202847A (d)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6126649U (ja) * 1984-07-23 1986-02-17 トヨタ自動車株式会社 室内鏡取付構造
JPS6126647U (ja) * 1984-07-23 1986-02-17 トヨタ自動車株式会社 室内鏡取付構造
DE3573576D1 (en) * 1984-07-23 1989-11-16 Toyota Motor Co Ltd A rear view mirror assembly
JPS6126648U (ja) * 1984-07-23 1986-02-17 トヨタ自動車株式会社 室内鏡取付構造
WO1988002753A2 (en) * 1986-10-10 1988-04-21 Gist-Brocades N.V. 9-alpha-hydroxy steroids and process for their preparation
US4936533A (en) * 1988-11-15 1990-06-26 Donnelly Corporation Mounting assembly for vehicle accessories
JPH0523412Y2 (d) * 1989-07-14 1993-06-15
US5100095A (en) * 1991-03-01 1992-03-31 Donnelly Corporation Breakaway vehicle accessory mount
FR2701262B1 (fr) * 1993-02-05 1995-03-24 Roussel Uclaf Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires.
CN114195844B (zh) * 2021-12-29 2023-03-17 湖北武当安泰药业有限公司 一种去氢表雄酮的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
NL245860A (d) * 1958-11-28
US2961441A (en) * 1959-08-07 1960-11-22 Pfizer & Co C Process for producing 6beta-fluorosteroids
US3014938A (en) * 1959-09-07 1961-12-26 Syntex Sa Preparation of 16, 21-diacetate derivative of cyclopentanophenanthrene compounds
BE642575A (d) * 1963-01-16
US3127428A (en) * 1963-01-16 1964-03-31 Schering Corp Process for converting a 3-keto-delta-steroid to the corresponding 3-keto delta-compound
US3221033A (en) * 1964-07-07 1965-11-30 Schering Corp Novel process for the preparation of 1,5-bis-dehydro steroids
US3980778A (en) * 1973-10-25 1976-09-14 The Upjohn Company Anti-inflammatory steroid
US4041055A (en) * 1975-11-17 1977-08-09 The Upjohn Company Process for the preparation of 17α-hydroxyprogesterones and corticoids from androstenes
DE2558088C2 (de) * 1975-12-19 1985-05-30 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten
US4102907A (en) * 1977-03-07 1978-07-25 The Upjohn Company Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione
US4127596A (en) * 1977-04-11 1978-11-28 The Upjohn Company Non-aromatic oxygenated strong acid dehydration of 9α-hydroxyandrostenediones
US4188322A (en) * 1978-04-28 1980-02-12 Blasinachim S.P.A. Process for the preparation of 6-halo-pregnanes
FR2433536A1 (fr) * 1978-08-16 1980-03-14 Roussel Uclaf Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
GB2102805A (en) 1983-02-09
US4383947A (en) 1983-05-17
FR2530641A1 (fr) 1984-01-27
CH651053A5 (de) 1985-08-30
JPH0517497A (ja) 1993-01-26
GB2152058A (en) 1985-07-31
GB2102805B (en) 1985-09-04
JPH0211600B2 (d) 1990-03-14
JPH0276896A (ja) 1990-03-16
GB2152058B (en) 1986-01-02
JPS5824595A (ja) 1983-02-14
NL8202847A (nl) 1983-02-16
IT8248845A0 (it) 1982-07-19
JPH0689021B2 (ja) 1994-11-09
DE3226164A1 (de) 1983-02-03
DE3226164C2 (d) 1992-07-02
GB8421987D0 (en) 1984-10-03
IT1157224B (it) 1987-02-11
FR2530641B1 (fr) 1987-03-06

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