JPH0472807B2 - - Google Patents

Info

Publication number
JPH0472807B2
JPH0472807B2 JP58078300A JP7830083A JPH0472807B2 JP H0472807 B2 JPH0472807 B2 JP H0472807B2 JP 58078300 A JP58078300 A JP 58078300A JP 7830083 A JP7830083 A JP 7830083A JP H0472807 B2 JPH0472807 B2 JP H0472807B2
Authority
JP
Japan
Prior art keywords
medium
molecular weight
cultured
human
malignant tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58078300A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59204122A (ja
Inventor
Tomoyuki Tajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koken Co Ltd
Original Assignee
Koken Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koken Co Ltd filed Critical Koken Co Ltd
Priority to JP58078300A priority Critical patent/JPS59204122A/ja
Priority to US06/583,011 priority patent/US4595657A/en
Priority to EP84303035A priority patent/EP0125125A3/en
Publication of JPS59204122A publication Critical patent/JPS59204122A/ja
Publication of JPH0472807B2 publication Critical patent/JPH0472807B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/91Cell lines ; Processes using cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP58078300A 1983-05-06 1983-05-06 人の悪性腫瘍細胞増殖抑制剤の製造方法 Granted JPS59204122A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP58078300A JPS59204122A (ja) 1983-05-06 1983-05-06 人の悪性腫瘍細胞増殖抑制剤の製造方法
US06/583,011 US4595657A (en) 1983-05-06 1984-02-23 Process for preparing an inhibiting agent against proliferation of animals malignant tumor cells
EP84303035A EP0125125A3 (en) 1983-05-06 1984-05-04 An agent for inhibiting the proliferation of malignant tumour cells and a process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58078300A JPS59204122A (ja) 1983-05-06 1983-05-06 人の悪性腫瘍細胞増殖抑制剤の製造方法

Publications (2)

Publication Number Publication Date
JPS59204122A JPS59204122A (ja) 1984-11-19
JPH0472807B2 true JPH0472807B2 (https=) 1992-11-19

Family

ID=13658070

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58078300A Granted JPS59204122A (ja) 1983-05-06 1983-05-06 人の悪性腫瘍細胞増殖抑制剤の製造方法

Country Status (3)

Country Link
US (1) US4595657A (https=)
EP (1) EP0125125A3 (https=)
JP (1) JPS59204122A (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5933223A (ja) * 1982-08-20 1984-02-23 Koken Kk 人の悪性腫瘍細胞増殖抑制剤
JPS59162889A (ja) * 1983-03-07 1984-09-13 Koken Kk 人の悪性腫瘍細胞の増殖抑制剤の製造方法
JPS6028930A (ja) * 1983-07-28 1985-02-14 Koken Kk 人の癌由来細胞の増殖抑制剤の精製方法
JPS6028931A (ja) * 1983-07-28 1985-02-14 Koken Kk ヒト腎細胞癌由来樹立株細胞の増殖抑制剤の濃縮方法
JP2004155670A (ja) * 2002-11-01 2004-06-03 Youichirou Naganushi 細胞賦活剤、細胞賦活剤製造方法及びその装置
RU2283654C1 (ru) * 2005-03-30 2006-09-20 Борис Владимирович Афанасьев Способ получения ростовых факторов белковой природы, ростовой фактор белковой природы и ингибитор пролиферации фибробластов
CA3078175C (en) * 2017-10-05 2023-06-20 Medical Corporation Ichikawa Clinic Method for preparing cell extract component or composition having cytocidal activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415553A (en) * 1973-08-06 1983-11-15 Dso "Pharmachim" Compositions, processes for their preparation and method for treatment of neoplasms
FR2302747B1 (fr) * 1975-03-03 1978-09-22 Inst Nat Sante Rech Med Procede d'obtention, a partir de macrophages de mammiferes, d'un produit therapeutique actif, notamment, a l'egard des cellules tumorales humaines et produit therapeutique ainsi obtenu
JPS58138383A (ja) * 1982-02-13 1983-08-17 Nippon Shinyaku Co Ltd 生理活性物質の製法
JPS5933223A (ja) * 1982-08-20 1984-02-23 Koken Kk 人の悪性腫瘍細胞増殖抑制剤
JPS59162889A (ja) * 1983-03-07 1984-09-13 Koken Kk 人の悪性腫瘍細胞の増殖抑制剤の製造方法

Also Published As

Publication number Publication date
US4595657A (en) 1986-06-17
JPS59204122A (ja) 1984-11-19
EP0125125A2 (en) 1984-11-14
EP0125125A3 (en) 1986-10-08

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