JPH0448438B2 - - Google Patents
Info
- Publication number
- JPH0448438B2 JPH0448438B2 JP63015695A JP1569588A JPH0448438B2 JP H0448438 B2 JPH0448438 B2 JP H0448438B2 JP 63015695 A JP63015695 A JP 63015695A JP 1569588 A JP1569588 A JP 1569588A JP H0448438 B2 JPH0448438 B2 JP H0448438B2
- Authority
- JP
- Japan
- Prior art keywords
- enzyme
- fibers
- immobilized
- enzymes
- immobilized enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004190 Enzymes Human genes 0.000 claims description 59
- 108090000790 Enzymes Proteins 0.000 claims description 59
- 239000000835 fiber Substances 0.000 claims description 38
- 108010093096 Immobilized Enzymes Proteins 0.000 claims description 17
- 239000004952 Polyamide Substances 0.000 claims description 12
- 229920002647 polyamide Polymers 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 6
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 4
- 238000006555 catalytic reaction Methods 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 3
- 125000000524 functional group Chemical group 0.000 claims description 3
- 108700023418 Amidases Proteins 0.000 claims description 2
- 108010001336 Horseradish Peroxidase Proteins 0.000 claims description 2
- 102000005922 amidase Human genes 0.000 claims description 2
- 230000001588 bifunctional effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229940088598 enzyme Drugs 0.000 description 51
- 239000004744 fabric Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 9
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 6
- 108010051210 beta-Fructofuranosidase Proteins 0.000 description 6
- 239000001573 invertase Substances 0.000 description 6
- 235000011073 invertase Nutrition 0.000 description 6
- 229920001778 nylon Polymers 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000003100 immobilizing effect Effects 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 239000004677 Nylon Substances 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 4
- 229930006000 Sucrose Natural products 0.000 description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 4
- 239000007822 coupling agent Substances 0.000 description 4
- -1 polypropylene Polymers 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 239000005720 sucrose Substances 0.000 description 4
- 229920002302 Nylon 6,6 Polymers 0.000 description 3
- URLKBWYHVLBVBO-UHFFFAOYSA-N Para-Xylene Chemical group CC1=CC=C(C)C=C1 URLKBWYHVLBVBO-UHFFFAOYSA-N 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 229920002284 Cellulose triacetate Polymers 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000012429 reaction media Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 2
- GAWAYYRQGQZKCR-UHFFFAOYSA-N 2-chloropropionic acid Chemical compound CC(Cl)C(O)=O GAWAYYRQGQZKCR-UHFFFAOYSA-N 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 102000001390 Fructose-Bisphosphate Aldolase Human genes 0.000 description 1
- 108010068561 Fructose-Bisphosphate Aldolase Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 102000005731 Glucose-6-phosphate isomerase Human genes 0.000 description 1
- 108010070600 Glucose-6-phosphate isomerase Proteins 0.000 description 1
- 102000005548 Hexokinase Human genes 0.000 description 1
- 108700040460 Hexokinases Proteins 0.000 description 1
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 description 1
- HRNLUBSXIHFDHP-UHFFFAOYSA-N N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide Chemical compound NC1=CC=CC=C1NC(=O)C(C=C1)=CC=C1CNC1=NC=CC(C=2C=NC=CC=2)=N1 HRNLUBSXIHFDHP-UHFFFAOYSA-N 0.000 description 1
- 229920000571 Nylon 11 Polymers 0.000 description 1
- 102000001253 Protein Kinase Human genes 0.000 description 1
- 108020000005 Sucrose phosphorylase Proteins 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 239000012295 chemical reaction liquid Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- LRPQMNYCTSPGCX-UHFFFAOYSA-N dimethyl pimelimidate Chemical compound COC(=N)CCCCCC(=N)OC LRPQMNYCTSPGCX-UHFFFAOYSA-N 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000009229 glucose formation Effects 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 229940116871 l-lactate Drugs 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 1
- 229920005594 polymer fiber Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 239000008057 potassium phosphate buffer Substances 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 108060006633 protein kinase Proteins 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- RPOHBMAQTOJHKM-UHFFFAOYSA-M sodium;2-chloropropanoate Chemical compound [Na+].CC(Cl)C([O-])=O RPOHBMAQTOJHKM-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 238000012289 standard assay Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
Landscapes
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
Description
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Claims (1)
- ãç¹èš±è«æ±ã®ç¯å²ã ïŒ ïŒçš®åã¯ïŒçš®ä»¥äžã®é µçŽ ã®ååãæ§é ç©äžã®
è¡šé¢ã«äœçœ®ããååŠçã«æŽ»æ§ãªåºã«çµåããŠãã
åºå®åé µçŽ æ§é ç©ã§ãã€ãŠããã®æ§é ç©ã¯äºãã«
é¢éããŠãããçžäºã«ã©ã³ãã ã«é£çµãããŠã
ããç¹ç¶ã®è»žã«å¯ŸããŠå®è³ªçã«æŽåããŠããããª
ã¢ãããã€ããªã«ãããªãçè玡糞ããªã¢ããç¹
ç¶ããæ§æãããŠããåèšåºå®åé µçŽ æ§é ç©ã ïŒ ïŒçš®åã¯ïŒçš®ä»¥äžã®é µçŽ ã®ååããé µçŽ äžã®
å®èœåºãããªã¢ãããã€ããªã«äžã®éé¢ã¢ãã³æ«
端ã«çµåãããè¬å€ã«ãã€ãŠæ§é ç©äžã®è¡šé¢ã«äœ
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æ±ã®ç¯å²ç¬¬ïŒé ã«èšèŒã®åºå®åé µçŽ æ§é ç©ã ïŒ è¬å€ãã°ã«ã¿ã«ã¢ã«ãããåã¯äºå®èœæ§ãžã€
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é ç©äžã®è¡šé¢ã«äœçœ®ããååŠçã«æŽ»æ§ãªåºã«å ±æ
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ã®æ§é ç©ã¯äºãã«é¢éããŠãããçžäºã«ã©ã³ãã
ã«é£çµãããŠãããç¹ç¶ã®è»žã«å¯ŸããŠå®è³ªçã«æŽ
åããŠããããªã¢ãããã€ããªã«ãããªãçè玡
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çŽ è§Šåªåå¿ãå®æœããããã®æ¹æ³ã
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8701706 | 1987-01-27 | ||
GB878701706A GB8701706D0 (en) | 1987-01-27 | 1987-01-27 | Immobilisation of enzymes |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS63202383A JPS63202383A (ja) | 1988-08-22 |
JPH0448438B2 true JPH0448438B2 (ja) | 1992-08-06 |
Family
ID=10611255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63015695A Granted JPS63202383A (ja) | 1987-01-27 | 1988-01-26 | é µçŽ ã®åºå®å |
Country Status (8)
Country | Link |
---|---|
US (1) | US4968605A (ja) |
EP (1) | EP0276560A1 (ja) |
JP (1) | JPS63202383A (ja) |
DK (1) | DK40688A (ja) |
FI (1) | FI880130A (ja) |
GB (1) | GB8701706D0 (ja) |
NO (1) | NO880320L (ja) |
ZA (1) | ZA8876B (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6324998A (en) * | 1997-02-13 | 1998-09-08 | Dow Chemical Company, The | Recombinant haloaliphatic dehalogenases |
GB9926419D0 (en) * | 1999-11-08 | 2000-01-12 | Downstream Media Limited | Methods and apparatus for capturing target substances from liquid media |
US7880247B2 (en) * | 2003-12-29 | 2011-02-01 | Vladimir Vaganov | Semiconductor input control device |
US8889373B2 (en) | 2010-08-12 | 2014-11-18 | Eastman Chemical Company | Enzyme catalyst immobilized on porous fluoropolymer support |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5526900A (en) * | 1978-08-15 | 1980-02-26 | Ici Ltd | Fixed enzyme preparation and method |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3716614A (en) * | 1969-05-12 | 1973-02-13 | Toray Industries | Process of manufacturing collagen fiber-like synthetic superfine filament bundles |
GB1485123A (en) * | 1974-07-25 | 1977-09-08 | Nat Res Dev | Support for biologically active material |
AT360680B (de) * | 1978-04-04 | 1981-01-26 | Tisza Bela & Co | Deckel fuer zwischengefaesse und masse zur herstellung des deckels |
GB2019410B (en) * | 1978-04-19 | 1982-06-03 | Novo Industri As | Immobilized enzyme products |
EP0011437B1 (en) * | 1978-11-20 | 1983-06-22 | Imperial Chemical Industries Plc | A process for setting a product comprising electrostatically spun fibres, and products prepared according to this process |
EP0080274B1 (en) * | 1981-11-23 | 1986-05-14 | Imperial Chemical Industries Plc | Process of melt spinning of a blend of a fibre-forming polymer and an immiscible polymer and melt spun fibres produced by such process |
ATE87329T1 (de) * | 1984-10-25 | 1993-04-15 | Ici Plc | Enzyme. |
JPS61149085A (ja) * | 1984-12-24 | 1986-07-07 | Chiyoda Chem Eng & Constr Co Ltd | 埮çç©æ æäœ |
US4657742A (en) * | 1985-07-01 | 1987-04-14 | Ppg Industries, Inc. | Packed fiber glass reaction vessel |
US4757014A (en) * | 1985-11-08 | 1988-07-12 | Minnesota Mining And Manufacturing Company | Immobilization of biologically active protein on a polymeric fibrous support |
ES2029475T3 (es) * | 1986-05-16 | 1992-08-16 | Imperial Chemical Industries Plc | Fibras y tubos fibrosos huecos. |
GB8630012D0 (en) * | 1986-12-16 | 1987-01-28 | Ici Plc | Decomposition of acrylamide |
GB8630029D0 (en) * | 1986-12-16 | 1987-01-28 | Ici Plc | Decomposition of acrylamide |
-
1987
- 1987-01-27 GB GB878701706A patent/GB8701706D0/en active Pending
- 1987-12-17 EP EP87311134A patent/EP0276560A1/en not_active Ceased
- 1987-12-22 US US07/136,353 patent/US4968605A/en not_active Expired - Fee Related
-
1988
- 1988-01-06 ZA ZA8876A patent/ZA8876B/xx unknown
- 1988-01-13 FI FI880130A patent/FI880130A/fi not_active Application Discontinuation
- 1988-01-26 JP JP63015695A patent/JPS63202383A/ja active Granted
- 1988-01-26 NO NO880320A patent/NO880320L/no unknown
- 1988-01-27 DK DK040688A patent/DK40688A/da not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5526900A (en) * | 1978-08-15 | 1980-02-26 | Ici Ltd | Fixed enzyme preparation and method |
Also Published As
Publication number | Publication date |
---|---|
GB8701706D0 (en) | 1987-03-04 |
DK40688A (da) | 1988-07-28 |
FI880130A (fi) | 1988-07-28 |
EP0276560A1 (en) | 1988-08-03 |
ZA8876B (en) | 1988-11-30 |
FI880130A0 (fi) | 1988-01-13 |
US4968605A (en) | 1990-11-06 |
JPS63202383A (ja) | 1988-08-22 |
DK40688D0 (da) | 1988-01-27 |
NO880320D0 (no) | 1988-01-26 |
NO880320L (no) | 1988-07-28 |
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