JPH0411215B2 - - Google Patents
Info
- Publication number
- JPH0411215B2 JPH0411215B2 JP59200131A JP20013184A JPH0411215B2 JP H0411215 B2 JPH0411215 B2 JP H0411215B2 JP 59200131 A JP59200131 A JP 59200131A JP 20013184 A JP20013184 A JP 20013184A JP H0411215 B2 JPH0411215 B2 JP H0411215B2
- Authority
- JP
- Japan
- Prior art keywords
- bone
- hydroxyapatite
- artificial
- particle size
- physiological saline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000988 bone and bone Anatomy 0.000 claims description 58
- 239000000463 material Substances 0.000 claims description 29
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 26
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 26
- 239000011148 porous material Substances 0.000 claims description 18
- 239000002245 particle Substances 0.000 claims description 16
- 239000002504 physiological saline solution Substances 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 description 16
- 238000001356 surgical procedure Methods 0.000 description 11
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 9
- 230000007547 defect Effects 0.000 description 8
- 239000002002 slurry Substances 0.000 description 6
- 206010072170 Skin wound Diseases 0.000 description 5
- 239000001506 calcium phosphate Substances 0.000 description 5
- 229910000389 calcium phosphate Inorganic materials 0.000 description 5
- 235000011010 calcium phosphates Nutrition 0.000 description 5
- 239000001913 cellulose Substances 0.000 description 5
- 229920002678 cellulose Polymers 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000010304 firing Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000000399 orthopedic effect Effects 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 229910052586 apatite Inorganic materials 0.000 description 2
- -1 calcium phosphate compound Chemical class 0.000 description 2
- 210000002808 connective tissue Anatomy 0.000 description 2
- 210000004373 mandible Anatomy 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000000963 osteoblast Anatomy 0.000 description 2
- 210000002997 osteoclast Anatomy 0.000 description 2
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 2
- 210000003460 periosteum Anatomy 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 208000006735 Periostitis Diseases 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 230000010072 bone remodeling Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 210000001564 haversian system Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59200131A JPS6179464A (ja) | 1984-09-25 | 1984-09-25 | 人工骨材料用組成物 |
| US06/770,722 US4629464A (en) | 1984-09-25 | 1985-08-29 | Porous hydroxyapatite material for artificial bone substitute |
| DE19853531144 DE3531144A1 (de) | 1984-09-25 | 1985-08-30 | Poroeses hydroxyapatitmaterial und seine verwendung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59200131A JPS6179464A (ja) | 1984-09-25 | 1984-09-25 | 人工骨材料用組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62266204A Division JPS63294864A (ja) | 1987-10-23 | 1987-10-23 | 人工骨材料の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6179464A JPS6179464A (ja) | 1986-04-23 |
| JPH0411215B2 true JPH0411215B2 (sv) | 1992-02-27 |
Family
ID=16419317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59200131A Granted JPS6179464A (ja) | 1984-09-25 | 1984-09-25 | 人工骨材料用組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6179464A (sv) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62281953A (ja) * | 1986-05-28 | 1987-12-07 | 旭光学工業株式会社 | 骨補填材 |
| JPH062153B2 (ja) * | 1987-09-18 | 1994-01-12 | 三菱マテリアル株式会社 | 骨欠損部及び骨空隙部充てん材 |
| JPH021285A (ja) * | 1988-01-11 | 1990-01-05 | Asahi Optical Co Ltd | 固着可能な歯科用及び医科用顆粒状骨補填材、その固着方法及び骨補填物 |
| JP2694372B2 (ja) * | 1988-12-12 | 1997-12-24 | ウロプラスティ，インコーポレイテッド | 微小移植物質 |
| JP2657847B2 (ja) * | 1990-05-10 | 1997-09-30 | 寅雄 大塚 | 水酸化アパタイト多孔質生体充▲てん▼材並びにその製造方法 |
| JPH0440961A (ja) * | 1990-06-06 | 1992-02-12 | Mitsubishi Materials Corp | 骨欠損部及び骨空隙部ならびに骨吸収部充填材 |
| JPH0930988A (ja) * | 1995-07-21 | 1997-02-04 | Sumitomo Osaka Cement Co Ltd | 薬剤徐放性多孔質セラミックス成形体及びその製造方法 |
| BRPI0510048A (pt) * | 2004-04-23 | 2007-10-16 | Jacobus Adriaan Albertus Kotze | agente de formação de massa de tecido, dispositivo para a formação de massa de uma porção de tecido, uso de um agente de formação de massa de tecido, e, métodos de tratamento de distúrbios relacionados à incontinência, e de formação de massa de uma porção de tecido |
| JP2008173238A (ja) * | 2007-01-17 | 2008-07-31 | Olympus Terumo Biomaterials Corp | 生体組織補填材の製造方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60142857A (ja) * | 1983-12-29 | 1985-07-29 | 住友セメント株式会社 | 骨セメント組成物 |
-
1984
- 1984-09-25 JP JP59200131A patent/JPS6179464A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60142857A (ja) * | 1983-12-29 | 1985-07-29 | 住友セメント株式会社 | 骨セメント組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6179464A (ja) | 1986-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |