JPH0377557A - Medicine-filled container - Google Patents
Medicine-filled containerInfo
- Publication number
- JPH0377557A JPH0377557A JP1215766A JP21576689A JPH0377557A JP H0377557 A JPH0377557 A JP H0377557A JP 1215766 A JP1215766 A JP 1215766A JP 21576689 A JP21576689 A JP 21576689A JP H0377557 A JPH0377557 A JP H0377557A
- Authority
- JP
- Japan
- Prior art keywords
- vial
- drug
- injection needle
- hub
- flange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 45
- 229940079593 drug Drugs 0.000 title claims description 42
- 239000007924 injection Substances 0.000 claims abstract description 28
- 238000002347 injection Methods 0.000 claims abstract description 28
- 229920001971 elastomer Polymers 0.000 claims abstract description 17
- 239000005060 rubber Substances 0.000 claims abstract description 17
- 239000012530 fluid Substances 0.000 claims abstract description 5
- 230000001012 protector Effects 0.000 claims description 3
- 239000000243 solution Substances 0.000 abstract description 20
- -1 polyethylene Polymers 0.000 description 8
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 4
- 238000004090 dissolution Methods 0.000 description 4
- 239000003978 infusion fluid Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 229920000573 polyethylene Polymers 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000002246 antineoplastic agent Substances 0.000 description 3
- 229940041181 antineoplastic drug Drugs 0.000 description 3
- 239000010836 blood and blood product Substances 0.000 description 3
- 229940125691 blood product Drugs 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000057 synthetic resin Substances 0.000 description 2
- 229920003002 synthetic resin Polymers 0.000 description 2
- 241000270722 Crocodylidae Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 229920000459 Nitrile rubber Polymers 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 229920006311 Urethane elastomer Polymers 0.000 description 1
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- LNNWVNGFPYWNQE-GMIGKAJZSA-N desomorphine Chemical compound C1C2=CC=C(O)C3=C2[C@]24CCN(C)[C@H]1[C@@H]2CCC[C@@H]4O3 LNNWVNGFPYWNQE-GMIGKAJZSA-N 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 239000008151 electrolyte solution Substances 0.000 description 1
- 229940021013 electrolyte solution Drugs 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229920003049 isoprene rubber Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
Description
【発明の詳細な説明】
〈産業上の利用分野〉
本発明は薬剤入り容器に関し、詳しくは内部に収納され
た制癌剤や抗生物質、血液製剤などの粉末状または凍結
乾燥された薬剤を使用直前に溶解して薬液を調剤するた
めに用いる薬剤入り容器に関する。[Detailed Description of the Invention] <Industrial Application Field> The present invention relates to a container containing a drug, and more specifically, the present invention relates to a container containing a drug, and more specifically, a container containing powdered or freeze-dried drugs such as anticancer drugs, antibiotics, blood products, etc., stored therein, which can be used immediately before use. This invention relates to a drug container used for dissolving and preparing a drug solution.
〈従来の技術〉
痢院等の医療機関においては、従来より、バイアル等の
容器に入った制癌剤や抗生物質、血液製剤などの粉末薬
剤あるいは凍結乾燥薬剤は、そのまま輸液剤に混注して
用いると配合割合が変化しやすく、また液状の薬剤とし
て保存しておくと薬効が低下するという問題があるため
、これを使用直前に溶解して輸液剤として点滴治療に用
いているが、薬剤の溶解操作は、上記薬剤の入った容器
とその薬剤を溶かす溶解液の入った容器とを両頭針ある
いは連結管等の接続用具を用いて接続し、溶解液を薬剤
の入った容器に移すことにより行っている。ところがこ
の操作は複雑で手間がかかる上に、薬剤の入った容器に
接続するための穴を明ける操作を外気中で行うので、中
の薬剤が汚染される虞があり問題である。<Prior art> In medical institutions such as gastroenterology clinics, powdered or freeze-dried drugs such as anticancer drugs, antibiotics, and blood products in containers such as vials have traditionally been mixed with infusion solutions and used as is. Since the compounding ratio is easy to change and the drug efficacy decreases if stored as a liquid drug, it is dissolved immediately before use and used as an infusion solution for drip treatment, but the drug dissolution process is difficult. This is done by connecting the container containing the drug mentioned above and the container containing the solution to dissolve the drug using a connecting tool such as a double-ended needle or connecting tube, and then transferring the solution to the container containing the drug. There is. However, this operation is complicated and time-consuming, and since the hole for connecting to the container containing the drug is performed in the open air, there is a risk that the drug inside may be contaminated, which poses a problem.
〈発明が解決しようとする課題〉
本発明はかかる事情に鑑みてなされたもので、薬剤の溶
解操作を無菌的に、容易かつ短時間で行うことのできる
安価な薬剤入り容器を提供することを目的とする。<Problems to be Solved by the Invention> The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an inexpensive drug-containing container in which the dissolution operation of drugs can be performed aseptically, easily, and in a short time. purpose.
く課題を解決するための手段〉
本発明は上記の課題を解決するために、口部に幅広の鍔
を有する予め溶解液の充填されたバイアルと、績バイア
ルの口部に挿着されて該口部を密封する注入針からなる
容器であって、前記注入針は１つの刃先と２つの流体通
路を有する中空針であり、その長手方向と垂直に前記バ
イアルの鍔より若干中さな外径を有する鍔状のハブが形
成されるとともに、該注入針の刃先側には該ハブに嵌着
固定されたゴムキャップが被冠されており、前記バイア
ルの鐸に前記ゴムキャップの被冠された注入針がそのハ
ブ部分で刃先が上になるように［２され、バイアルの鍔
とゴムキャップの被冠されたハブとがキャップ部材で固
定されてなる薬剤入り容器を採用している。Means for Solving the Problems> In order to solve the above problems, the present invention provides a vial having a wide brim at the mouth and pre-filled with a dissolving solution, and a vial that is inserted into the mouth of the vial. A container consisting of an injection needle whose mouth is sealed, the injection needle being a hollow needle having one cutting edge and two fluid passages, and having an outer diameter slightly smaller than the flange of the vial perpendicular to its longitudinal direction. A brim-shaped hub is formed, and the cutting edge side of the injection needle is covered with a rubber cap that is fitted and fixed to the hub, and the vial cap is covered with the rubber cap. The drug-containing container is such that the injection needle is positioned so that its cutting edge is upward at the hub portion, and the vial flange and the hub covered with a rubber cap are fixed by a cap member.
〈作用〉
上記構成によれば、使用に際して、薬剤入り容器からプ
ロテクターキャップを外し、薬剤入り容器の注入針に上
方から溶解液容器の口部をあてがい口部閉鎖体を注入針
で刺通すれば、薬剤入り容器と溶解液容器とが連通して
溶解液容器の熔解液が重力により薬剤入り容器側に移行
し、中に収容されている注射剤（制癌剤や抗生物質、血
液製剤など）を溶解する。溶解後薬剤入り容器内の薬液
は注射器などで吸り１して注射剤として、または輸液剤
として単独または他の輸液剤に混注して用いることがで
きる。また薬液を他の薬剤の溶解に使用することもでき
る。<Operation> According to the above configuration, when in use, remove the protector cap from the drug container, place the opening of the solution container from above onto the injection needle of the drug container, and pierce the opening closure with the injection needle. The drug container and the solution container communicate with each other, and the solution in the solution container moves by gravity to the drug container, dissolving the injectables (anticancer drugs, antibiotics, blood products, etc.) contained therein. do. After dissolution, the drug solution in the drug-containing container can be drawn into a syringe or the like and used as an injection, or as an infusion solution, either alone or mixed with another infusion solution. The drug solution can also be used to dissolve other drugs.
〈実施例〉 次に本発明の実施例について図面に基づいて説明する。<Example> Next, embodiments of the present invention will be described based on the drawings.
第１図は本発明の一実施例に係る薬剤入り容器の説明図
である。FIG. 1 is an explanatory diagram of a drug-containing container according to an embodiment of the present invention.
図に示すように本発明の薬剤入り容器は、薬剤（Ｄ）の
収容された口部に幅広の鐸（３）を有するバイアル（１
）とこのバイアル（１）の口部に挿入して取り付けられ
た口部を密封する注入針（２）とからなっている、そし
て注入針（２）は１つの刃先（４）と２つの流体通路（
７）、（８）およびハブ（５）を有しており、注入針（
２）をカバーするゴムキャップ（６）がハブ（５）に嵌
め込まれて固定されている。そしてさらにゴムキャップ
付の注入針（２）はそのハブ（５）の部分でバイアル（
１）の鍔（３）にキャップ部材（９）によって固定され
ている。As shown in the figure, the drug-containing container of the present invention includes a vial (1
) and an injection needle (2) inserted into and attached to the mouth of the vial (1) to seal the mouth, and the injection needle (2) has one cutting edge (4) and two fluids. aisle(
7), (8) and a hub (5), and has an injection needle (
A rubber cap (6) covering the hub (5) is fitted and fixed to the hub (5). Furthermore, the injection needle (2) with a rubber cap is attached to the hub (5) of the vial (
1) is fixed to the collar (3) by a cap member (9).
バイアル（１）は粉末状の薬剤や凍結乾燥されたＩ荊（
Ｄ）を収納する容器であり、その口部には幅の広い鰐（
３）が形成されており、鍔（３）の大きさはこの上に宣
かれるゴムキャップ（６）付ハブ（５）の大きさと略等
しくなっている。バイアル（１）には必要に応じて内部
の薬剤が変質しないよう褐色の着色を施しておいてもよ
い、バイアル（１）の形成材料としてはガス不透過性を
有しかつ耐薬品性を有するものであれば特に限定されな
いが、一般にポリエチレンやポリプロピレンなどの合成
樹脂や、ガラスなどが好適に使用される。Vial (1) contains powdered drugs and freeze-dried Ijing (
It is a container that stores D), and its mouth has a wide crocodile (
3), and the size of the flange (3) is approximately equal to the size of the hub (5) with a rubber cap (6) attached thereon. If necessary, the vial (1) may be colored brown to prevent the drug inside from deteriorating.The material for forming the vial (1) has gas impermeability and chemical resistance. Although there are no particular limitations on the material, synthetic resins such as polyethylene and polypropylene, glass, and the like are generally suitably used.
注入針（２）は薬剤（Ｄ）の収納されたバイアル（１）
の中に溶解液容器（図示していない）に収容された溶解
液を導入するためのもので、１つの刃先（４）と２つの
流体通路（７）、（８）を有しており、中央やや下部（
刃先と反対側）寄りの部分に、鍔（３）の外径よりやや
小さな外径を有する円板状のハブ（５）が形成されてい
る。溶解液がバイアル内に移行する時には（７）は溶解
液の通路になり、（８）は空気の通路になる。ハブ（５
）は注入針（２）をバイアル（１）、正確にはバイアル
（１）の鍔（３）に固定するための部分であり、これに
ゴムキャップ（６）が嵌め込まれた後バイアル（１）の
鍔（３）に刃先（４）が上を向くように載置されてキャ
ップ部材（９）で固定される。尚、刃先（４）の形状に
ついては溶解液薬瓶の閉鎖体、たとえば閉鎖膜や栓体な
と、を刺通できるものであれば特に限定するものではな
い、注入針（２）の材質についても耐薬品性が良ければ
特に限定されるものではなく、一般にポリプロピレンや
ポリエチレン、アクリロニトリル−ブタジェン−スチレ
ン共重合体、ポリスチレン、ポリカーボネートなどが使
用される。The injection needle (2) is the vial (1) containing the drug (D)
It is for introducing the solution contained in the solution container (not shown) into the solution container, and has one cutting edge (4) and two fluid passages (7) and (8), Slightly lower center (
A disk-shaped hub (5) having an outer diameter slightly smaller than the outer diameter of the flange (3) is formed on the opposite side of the cutting edge. When the solution moves into the vial, (7) becomes a passage for the solution and (8) becomes a passage for air. Hub (5
) is a part for fixing the injection needle (2) to the vial (1), to be more precise, the collar (3) of the vial (1), and after the rubber cap (6) is fitted into this, the vial (1) is fixed. The cutting edge (4) is placed on the collar (3) with the cutting edge (4) facing upward and fixed with the cap member (9). The shape of the cutting edge (4) is not particularly limited as long as it can pierce the closing body of the solution vial, such as the closing membrane or the stopper. Regarding the material of the injection needle (2), The material is not particularly limited as long as it has good chemical resistance, and polypropylene, polyethylene, acrylonitrile-butadiene-styrene copolymer, polystyrene, polycarbonate, and the like are generally used.
ゴムキャップ（６）は薬剤（Ｄ）および注入針（２）を
無菌的に保護するもので、ゴム状弾性体のたとえば天然
ゴムやイソプレンゴム、ブタジェンゴム、スチレン−ブ
タジェンゴム、ニトリルゴム、ウレタンゴム、シリコー
ンゴムなどでチューブ状に形成されており、一端が閉鎖
し他端が注入針（２）のハブ（５）の形状に合わせて、
ノ＼ブ（５）を嵌入できるよう内径がコの字状に拡径さ
れている。The rubber cap (6) protects the drug (D) and the injection needle (2) in a sterile manner, and is made of rubber-like elastic materials such as natural rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, nitrile rubber, urethane rubber, and silicone. It is formed into a tube shape made of rubber or the like, and one end is closed and the other end matches the shape of the hub (5) of the injection needle (2).
The inner diameter is enlarged into a U-shape so that the knob (5) can be inserted into it.
キャップ部材（９）は注入針（２）をバイアル（１）に
固定するためのものであり、注入針（２）のゴムキャッ
プ（６）を嵌めたハブ（５）の部分とバイアル（１）の
＃ （３）とを外部から押さえ込んで固定する。キャッ
プ部材（９）の材質としては、一般にアルミニウムやた
とえばポリエチレン、ポリプロピレンなどの熱可撓性樹
脂が使用される。固定方法としては、アルミニウムキャ
ップの場合はかしめるようにして固定でき、熱可撓性樹
脂の場合には嵌合、熱による成形（溶融して絞り込む）
、螺合などが可能である。The cap member (9) is for fixing the injection needle (2) to the vial (1), and connects the part of the hub (5) fitted with the rubber cap (6) of the injection needle (2) and the vial (1). # (3) and secure it by pressing it from the outside. The cap member (9) is generally made of aluminum or a thermoflexible resin such as polyethylene or polypropylene. As for the fixing method, in the case of aluminum caps, it can be fixed by caulking, and in the case of thermoflexible resin, it can be fitted and formed by heat (melting and squeezing).
, screwing, etc. are possible.
プロテクターキャップ（ｌＯ）は刃先（４）を保護する
とともに、ゴムキャップ（６）の汚損およびゴムキャッ
プ（６）が刃先（４）によって破損するのを防ぐもので
あり、一般にポリプロピレンやポリエチレン、ポリスチ
レンなとの合成樹脂で形成される。但しゴムキャップ（
６）の汚損を防ぐ目的のためには薬剤入り容器全体をプ
ラスチックフィルムで包んだだけでもよい。The protector cap (lO) protects the cutting edge (4) and prevents the rubber cap (6) from becoming dirty and being damaged by the cutting edge (4), and is generally made of polypropylene, polyethylene, or polystyrene. It is made of synthetic resin. However, the rubber cap (
For the purpose of preventing contamination (6), it is sufficient to simply wrap the entire drug container with a plastic film.
尚、溶解液としては一般に生理食塩水や５％ブドウ糖液
、注射用蒸留水、各種電解質液などが使用される。As the dissolving solution, physiological saline, 5% glucose solution, distilled water for injection, various electrolyte solutions, etc. are generally used.
〈発明の効果〉
以上説明してきたことから明らかなように、本発明の薬
剤入り容器を用いることにより、粉末剤の飛散による病
院内の汚染を防止できる、薬剤の溶解操作を無菌的に、
容易かつ短時間で行うことができる、などの効果を奏す
ることができる。<Effects of the Invention> As is clear from the above explanation, by using the drug-containing container of the present invention, it is possible to aseptically perform the dissolution operation of drugs, which can prevent contamination in the hospital due to powder scattering.
This can be done easily and in a short time.
第１図は本発明の一実施例に係る薬剤入り容器の説明図
である。
〈符号の説明〉
１：バイアル ２：注入針
３：鍔 ４：刃先FIG. 1 is an explanatory diagram of a drug-containing container according to an embodiment of the present invention. <Explanation of symbols> 1: Vial 2: Injection needle 3: Tsuba 4: Blade tip
Claims (1)
アルと、該バイアルの口部に挿着されて該口部を密封す
る注入針からなる容器であって、前記注入針は１つの刃
先と２つの流体通路を有する中空針であり、その長手方
向と垂直に前記バイアルの鍔より若干小さな外径を有す
る鍔状のハブが形成されるとともに、該注入針の刃先側
には該ハブに嵌着固定されたゴムキャップが被冠されて
おり、 前記バイアルの鍔に前記ゴムキャップの被冠された注入
針がそのハブ部分で刃先が上になるように載置され、バ
イアルの鍔とキャップの被冠された注入針のハブとがキ
ャップ部材で固定されてなる薬剤入り容器。 ２）注入針がさらにキャップ部材に嵌合するプロテクタ
ーキャップで被冠されてなる請求項１記載の薬剤入り容
器。 ３）薬剤が粉末薬剤または凍結乾燥薬剤である請求項１
記載の薬剤入り容器。[Scope of Claims] 1) A container consisting of a vial having a wide brim at the mouth and containing a drug in advance, and an injection needle inserted into the mouth of the vial to seal the mouth, The injection needle is a hollow needle having one cutting edge and two fluid passages, and a flange-shaped hub having an outer diameter slightly smaller than the flange of the vial is formed perpendicular to the longitudinal direction of the needle. The blade edge side is covered with a rubber cap that is fitted and fixed to the hub, and the injection needle, which is covered with the rubber cap, is placed on the brim of the vial with the blade tip facing upward at the hub portion. A drug-containing container in which the flange of a vial and the hub of an injection needle covered with a cap are fixed by a cap member. 2) The drug-containing container according to claim 1, wherein the injection needle is further covered with a protector cap that fits into the cap member. 3) Claim 1, wherein the drug is a powdered drug or a freeze-dried drug.
Container containing the listed medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1215766A JP2749899B2 (en) | 1989-08-21 | 1989-08-21 | Medicine container |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1215766A JP2749899B2 (en) | 1989-08-21 | 1989-08-21 | Medicine container |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0377557A true JPH0377557A (en) | 1991-04-03 |
| JP2749899B2 JP2749899B2 (en) | 1998-05-13 |
Family
ID=16677876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1215766A Expired - Fee Related JP2749899B2 (en) | 1989-08-21 | 1989-08-21 | Medicine container |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2749899B2 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0339162A (en) * | 1989-07-07 | 1991-02-20 | Nissho Corp | Injection drug dissolving solution container |
-
1989
- 1989-08-21 JP JP1215766A patent/JP2749899B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0339162A (en) * | 1989-07-07 | 1991-02-20 | Nissho Corp | Injection drug dissolving solution container |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2749899B2 (en) | 1998-05-13 |
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