JPH037664B2 - - Google Patents

Info

Publication number
JPH037664B2
JPH037664B2 JP62244419A JP24441987A JPH037664B2 JP H037664 B2 JPH037664 B2 JP H037664B2 JP 62244419 A JP62244419 A JP 62244419A JP 24441987 A JP24441987 A JP 24441987A JP H037664 B2 JPH037664 B2 JP H037664B2
Authority
JP
Japan
Prior art keywords
previtamin
formula
compound
reaction
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62244419A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6399053A (ja
Inventor
Fuandeuare Mauritsutsu
Yaa Fuanmere Ruku
Jiii Do Kureruku Pieru
Yaa Harukesu Sebasuchianusu
Aaru Emu Oberubiiku Uiruherumusu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Publication of JPS6399053A publication Critical patent/JPS6399053A/ja
Publication of JPH037664B2 publication Critical patent/JPH037664B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP62244419A 1981-07-17 1987-09-30 １α―ヒドロキシ―プレビタミンＤ↓３ Granted JPS6399053A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8103393 1981-07-17
NL8103393 1981-07-17

Publications (2)

Publication Number Publication Date
JPS6399053A JPS6399053A (ja) 1988-04-30
JPH037664B2 true JPH037664B2 (zh:) 1991-02-04

Family

ID=19837798

Family Applications (3)

Application Number Title Priority Date Filing Date
JP57123065A Granted JPS5823660A (ja) 1981-07-17 1982-07-16 １α―ヒドロキシビタミンＤまたは１α―ヒドロキシ―プレビタミンＤ化合物の製造方法
JP62244419A Granted JPS6399053A (ja) 1981-07-17 1987-09-30 １α―ヒドロキシ―プレビタミンＤ↓３
JP62244420A Granted JPS63107964A (ja) 1981-07-17 1987-09-30 プロビタミンｄまたはタキステロール化合物とジエノフィルとの付加物およびその製造方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP57123065A Granted JPS5823660A (ja) 1981-07-17 1982-07-16 １α―ヒドロキシビタミンＤまたは１α―ヒドロキシ―プレビタミンＤ化合物の製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP62244420A Granted JPS63107964A (ja) 1981-07-17 1987-09-30 プロビタミンｄまたはタキステロール化合物とジエノフィルとの付加物およびその製造方法

Country Status (9)

Country Link
US (1) US4539153A (zh:)
EP (1) EP0070588B1 (zh:)
JP (3) JPS5823660A (zh:)
AT (1) ATE19623T1 (zh:)
CA (1) CA1327977C (zh:)
DE (1) DE3270978D1 (zh:)
DK (1) DK172151B1 (zh:)
ES (1) ES8308847A1 (zh:)
IL (1) IL66317A (zh:)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402982B1 (en) * 1989-06-15 1994-01-05 Duphar International Research B.V Adduct-aldehyde and its use for the preparation of a vitamin-D compound
CH681152A5 (de) * 1991-06-04 1993-01-29 Marigen S.A. Neue biotenside und antitumorale ester und phosphatide mit vitamin-d- und vitamin-e-verbindungen, ihre herstellung und aufarbeitung zu spontan dispergierbaren konzentraten.
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
JP3722832B2 (ja) * 1992-06-22 2005-11-30 ルーナー、コーポレーション 経口用１α−ヒドロキシプレビタミンＤ
IN188477B (zh:) * 1998-06-23 2002-09-28 Hoffmann La Roche
CA2481909C (en) * 2002-04-11 2013-07-02 Instytut Farmaceutyczny Preparation of 24-alkyl analogs of cholecalciferol
WO2005067673A2 (en) * 2004-01-06 2005-07-28 The University Of Tennessee Research Foundation Enzymatic method to produce 7-dehydropregnenolone, vitamin d3-like compounds and derivatives thereof
TW200714580A (en) * 2005-10-14 2007-04-16 Formosa Lab Inc Process for preparing vitamin D analogs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4022768A (en) * 1976-02-12 1977-05-10 Wisconsin Alumni Research Foundation Process for preparation of 1α,25-dihydroxycholecalciferol
US4110446A (en) * 1977-07-14 1978-08-29 Wisconsin Alumni Research Foundation Method of treating milk fever in dairy cattle with 1,25-dihydroxycholecalciferol
US4202829A (en) * 1978-01-05 1980-05-13 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4206131A (en) * 1978-06-19 1980-06-03 The Upjohn Company Compounds and process
JPS557215A (en) * 1978-06-30 1980-01-19 Teijin Ltd Preparation of active vitamin d3 or its oh-protected derivative and/or its corresponding previtamin d3 or its oh-protected derivative
PH16989A (en) * 1978-11-07 1984-05-04 Res Inst Medicine Chem Process for the preparation of 1-hydroxylated vitamin d compounds
US4335120A (en) * 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials

Also Published As

Publication number Publication date
DK315782A (da) 1983-01-18
IL66317A (en) 1987-07-31
JPH0420431B2 (zh:) 1992-04-02
JPS6399053A (ja) 1988-04-30
CA1327977C (en) 1994-03-22
EP0070588B1 (en) 1986-05-07
IL66317A0 (en) 1982-11-30
ES513950A0 (es) 1983-10-01
JPS63107964A (ja) 1988-05-12
JPH0339058B2 (zh:) 1991-06-12
ATE19623T1 (de) 1986-05-15
US4539153A (en) 1985-09-03
ES8308847A1 (es) 1983-10-01
EP0070588A1 (en) 1983-01-26
DE3270978D1 (en) 1986-06-12
DK172151B1 (da) 1997-12-01
JPS5823660A (ja) 1983-02-12

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