ES8308847A1 - "un metodo de preparar compuestos de 1&-hidroxivitamina d o 1&-hidroxi-previtamina d". - Google Patents
"un metodo de preparar compuestos de 1&-hidroxivitamina d o 1&-hidroxi-previtamina d".Info
- Publication number
- ES8308847A1 ES8308847A1 ES513950A ES513950A ES8308847A1 ES 8308847 A1 ES8308847 A1 ES 8308847A1 ES 513950 A ES513950 A ES 513950A ES 513950 A ES513950 A ES 513950A ES 8308847 A1 ES8308847 A1 ES 8308847A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- previtamin
- hydroxy
- adduct
- hydroxyvitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 tachysterol compound Chemical class 0.000 title abstract 4
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 title abstract 3
- YUGCAAVRZWBXEQ-WHTXLNIXSA-N previtamin D3 Chemical compound C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)CCCC(C)C)\C=C/C1=C(C)CC[C@H](O)C1 YUGCAAVRZWBXEQ-WHTXLNIXSA-N 0.000 title abstract 2
- BUNBVCKYYMRTNS-UHFFFAOYSA-N tachysterol Natural products C=1CCC2(C)C(C(C)CCC(C)C(C)C)CCC2C=1C=CC1=C(C)CCC(O)C1 BUNBVCKYYMRTNS-UHFFFAOYSA-N 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 125000002030 1,2-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([*:2])C([H])=C1[H] 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Obesity (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8103393 | 1981-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES513950A0 ES513950A0 (es) | 1983-10-01 |
| ES8308847A1 true ES8308847A1 (es) | 1983-10-01 |
Family
ID=19837798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES513950A Expired ES8308847A1 (es) | 1981-07-17 | 1982-07-14 | "un metodo de preparar compuestos de 1&-hidroxivitamina d o 1&-hidroxi-previtamina d". |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4539153A (zh:) |
| EP (1) | EP0070588B1 (zh:) |
| JP (3) | JPS5823660A (zh:) |
| AT (1) | ATE19623T1 (zh:) |
| CA (1) | CA1327977C (zh:) |
| DE (1) | DE3270978D1 (zh:) |
| DK (1) | DK172151B1 (zh:) |
| ES (1) | ES8308847A1 (zh:) |
| IL (1) | IL66317A (zh:) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0402982B1 (en) * | 1989-06-15 | 1994-01-05 | Duphar International Research B.V | Adduct-aldehyde and its use for the preparation of a vitamin-D compound |
| CH681152A5 (de) * | 1991-06-04 | 1993-01-29 | Marigen S.A. | Neue biotenside und antitumorale ester und phosphatide mit vitamin-d- und vitamin-e-verbindungen, ihre herstellung und aufarbeitung zu spontan dispergierbaren konzentraten. |
| US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
| JP3722832B2 (ja) * | 1992-06-22 | 2005-11-30 | ルーナー、コーポレーション | 経口用１α−ヒドロキシプレビタミンＤ |
| IN188477B (zh:) * | 1998-06-23 | 2002-09-28 | Hoffmann La Roche | |
| CA2481909C (en) * | 2002-04-11 | 2013-07-02 | Instytut Farmaceutyczny | Preparation of 24-alkyl analogs of cholecalciferol |
| WO2005067673A2 (en) * | 2004-01-06 | 2005-07-28 | The University Of Tennessee Research Foundation | Enzymatic method to produce 7-dehydropregnenolone, vitamin d3-like compounds and derivatives thereof |
| TW200714580A (en) * | 2005-10-14 | 2007-04-16 | Formosa Lab Inc | Process for preparing vitamin D analogs |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3901928A (en) * | 1973-01-10 | 1975-08-26 | Robert Henry Hesse | 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds |
| US3993675A (en) * | 1975-02-24 | 1976-11-23 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,25-dihydroxycholecalciferol |
| US4069321A (en) * | 1975-10-14 | 1978-01-17 | Merck & Co., Inc. | Blocked cholecalciferol and dihydrotachysterol 3 derivatives |
| US4022768A (en) * | 1976-02-12 | 1977-05-10 | Wisconsin Alumni Research Foundation | Process for preparation of 1α,25-dihydroxycholecalciferol |
| US4110446A (en) * | 1977-07-14 | 1978-08-29 | Wisconsin Alumni Research Foundation | Method of treating milk fever in dairy cattle with 1,25-dihydroxycholecalciferol |
| US4202829A (en) * | 1978-01-05 | 1980-05-13 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
| US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
| US4206131A (en) * | 1978-06-19 | 1980-06-03 | The Upjohn Company | Compounds and process |
| JPS557215A (en) * | 1978-06-30 | 1980-01-19 | Teijin Ltd | Preparation of active vitamin d3 or its oh-protected derivative and/or its corresponding previtamin d3 or its oh-protected derivative |
| PH16989A (en) * | 1978-11-07 | 1984-05-04 | Res Inst Medicine Chem | Process for the preparation of 1-hydroxylated vitamin d compounds |
| US4335120A (en) * | 1979-03-21 | 1982-06-15 | Hoffmann-La Roche Inc. | Administration of biologically active vitamin D3 and vitamin D2 materials |
-
1982
- 1982-07-05 EP EP82200833A patent/EP0070588B1/en not_active Expired
- 1982-07-05 AT AT82200833T patent/ATE19623T1/de not_active IP Right Cessation
- 1982-07-05 DE DE8282200833T patent/DE3270978D1/de not_active Expired
- 1982-07-14 IL IL66317A patent/IL66317A/xx not_active IP Right Cessation
- 1982-07-14 DK DK315782A patent/DK172151B1/da not_active IP Right Cessation
- 1982-07-14 ES ES513950A patent/ES8308847A1/es not_active Expired
- 1982-07-16 CA CA000407425A patent/CA1327977C/en not_active Expired - Fee Related
- 1982-07-16 JP JP57123065A patent/JPS5823660A/ja active Granted
-
1984
- 1984-07-31 US US06/636,782 patent/US4539153A/en not_active Expired - Lifetime
-
1987
- 1987-09-30 JP JP62244419A patent/JPS6399053A/ja active Granted
- 1987-09-30 JP JP62244420A patent/JPS63107964A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK315782A (da) | 1983-01-18 |
| IL66317A (en) | 1987-07-31 |
| JPH0420431B2 (zh:) | 1992-04-02 |
| JPS6399053A (ja) | 1988-04-30 |
| CA1327977C (en) | 1994-03-22 |
| EP0070588B1 (en) | 1986-05-07 |
| IL66317A0 (en) | 1982-11-30 |
| ES513950A0 (es) | 1983-10-01 |
| JPS63107964A (ja) | 1988-05-12 |
| JPH0339058B2 (zh:) | 1991-06-12 |
| ATE19623T1 (de) | 1986-05-15 |
| JPH037664B2 (zh:) | 1991-02-04 |
| US4539153A (en) | 1985-09-03 |
| EP0070588A1 (en) | 1983-01-26 |
| DE3270978D1 (en) | 1986-06-12 |
| DK172151B1 (da) | 1997-12-01 |
| JPS5823660A (ja) | 1983-02-12 |
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