JPH0355781B2 - - Google Patents
Info
- Publication number
- JPH0355781B2 JPH0355781B2 JP61503776A JP50377686A JPH0355781B2 JP H0355781 B2 JPH0355781 B2 JP H0355781B2 JP 61503776 A JP61503776 A JP 61503776A JP 50377686 A JP50377686 A JP 50377686A JP H0355781 B2 JPH0355781 B2 JP H0355781B2
- Authority
- JP
- Japan
- Prior art keywords
- nozzle
- glass
- flow
- orifice
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 claims abstract description 43
- 239000012530 fluid Substances 0.000 claims abstract description 26
- 239000011521 glass Substances 0.000 claims abstract description 17
- 239000002184 metal Substances 0.000 claims abstract 2
- 239000006059 cover glass Substances 0.000 claims description 20
- 230000003287 optical effect Effects 0.000 claims description 9
- 239000005357 flat glass Substances 0.000 claims description 5
- 230000005499 meniscus Effects 0.000 claims description 5
- 239000010419 fine particle Substances 0.000 claims description 4
- 239000011859 microparticle Substances 0.000 claims description 4
- 230000005484 gravity Effects 0.000 claims description 2
- 230000005611 electricity Effects 0.000 claims 1
- 238000009652 hydrodynamic focusing Methods 0.000 abstract description 4
- 238000000149 argon plasma sintering Methods 0.000 abstract description 3
- 238000005259 measurement Methods 0.000 description 17
- 230000035945 sensitivity Effects 0.000 description 8
- 230000005284 excitation Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 238000001514 detection method Methods 0.000 description 3
- 238000007654 immersion Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011882 ultra-fine particle Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Chairs Characterized By Structure (AREA)
- Special Spraying Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO852761 | 1985-07-10 | ||
| NO852761A NO156916C (no) | 1985-07-10 | 1985-07-10 | Stroemningskammer for vaeskestroemsfotometer. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62503192A JPS62503192A (ja) | 1987-12-17 |
| JPH0355781B2 true JPH0355781B2 (OSRAM) | 1991-08-26 |
Family
ID=19888388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61503776A Granted JPS62503192A (ja) | 1985-07-10 | 1986-07-10 | フロ−・サイトメ−タ−用のフロ−・チャンバ−装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4737025A (OSRAM) |
| EP (1) | EP0229814B1 (OSRAM) |
| JP (1) | JPS62503192A (OSRAM) |
| AT (1) | ATE43721T1 (OSRAM) |
| DE (1) | DE3663744D1 (OSRAM) |
| NO (1) | NO156916C (OSRAM) |
| WO (1) | WO1987000282A1 (OSRAM) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63262565A (ja) * | 1987-04-20 | 1988-10-28 | Hitachi Ltd | フロ−セル |
| EP0421406B1 (en) * | 1989-10-04 | 1996-02-14 | Canon Kabushiki Kaisha | Apparatus and method for separating or measuring particles to be examined in a sample fluid |
| US5275787A (en) * | 1989-10-04 | 1994-01-04 | Canon Kabushiki Kaisha | Apparatus for separating or measuring particles to be examined in a sample fluid |
| NO894680L (no) * | 1989-11-24 | 1991-05-27 | Flowtech A S V Harald Steen | Pulsmodulasjon av eksitasjonslyskilden i vaeskestroemcytofotometere. |
| DK111990D0 (da) * | 1990-05-04 | 1990-05-04 | Biometic Aps | Apparat og fremgangsmaade til analyse af en vaeskesuspension |
| JP3232145B2 (ja) * | 1991-12-27 | 2001-11-26 | シスメックス株式会社 | 網赤血球測定方法 |
| US5818731A (en) * | 1995-08-29 | 1998-10-06 | Mittal; Gauri S. | Method and apparatus for measuring quality of frying/cooking oil/fat |
| AU752985B2 (en) | 1997-01-31 | 2002-10-03 | Xy, Llc. | Optical apparatus |
| US5861950A (en) * | 1997-07-10 | 1999-01-19 | Particle Measuring Systems, Inc. | Particle detection system utilizing an inviscid flow-producing nozzle |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| US6263745B1 (en) * | 1999-12-03 | 2001-07-24 | Xy, Inc. | Flow cytometer nozzle and flow cytometer sample handling methods |
| WO2002043486A1 (en) | 2000-11-29 | 2002-06-06 | Xy, Inc. | System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| EP2284256A3 (en) * | 2002-08-01 | 2012-08-29 | Xy, Llc | Low pressure sperm separation system |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| JP2005535346A (ja) | 2002-08-15 | 2005-11-24 | エックスワイ，インコーポレイテッド | 高分解能フローサイトメーター |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| CA2518882C (en) | 2003-03-28 | 2017-05-09 | Monsanto Technology Llc | Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm |
| ES2541121T3 (es) | 2003-05-15 | 2015-07-16 | Xy, Llc | Clasificación eficiente de células haploides por sistemas de citometría de flujo |
| EP2801363B1 (en) | 2004-03-29 | 2018-02-21 | Inguran, LLC | Process for storing sorted spermatozoa |
| AU2005266930B2 (en) | 2004-07-22 | 2010-09-16 | Inguran, Llc | Process for enriching a population of sperm cells |
| WO2009073652A1 (en) | 2007-12-04 | 2009-06-11 | Particle Measuring Systems, Inc. | Two-dimensional optical imaging methods and systems for particle detection |
| US8589851B2 (en) * | 2009-12-15 | 2013-11-19 | Memoir Systems, Inc. | Intelligent memory system compiler |
| US8614793B2 (en) * | 2012-04-02 | 2013-12-24 | Ecolab Usa Inc. | Flow chamber for online fluorometer |
| US11668640B2 (en) | 2015-03-06 | 2023-06-06 | Inguran, Llc | Nozzle assembly for a flow cytometry system and methods of manufacture |
| WO2014046733A1 (en) | 2012-09-19 | 2014-03-27 | Inguran, Llc | Nozzle assembly for a flow cytometer system and methods of manufacture |
| JP2015531878A (ja) | 2012-09-19 | 2015-11-05 | イングラン， エルエルシー | フローサイトメータノズル先端 |
| CN109295185B (zh) * | 2018-09-05 | 2022-03-22 | 暨南大学 | 一种适用于单细胞真核藻类基因组大小的测定方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2709399C3 (de) * | 1977-03-04 | 1980-07-24 | Goehde, Wolfgang, Dr., 4400 Muenster | Einrichtung zum Messen von Zelleigenschaften |
| DE2853703A1 (de) * | 1978-12-13 | 1980-07-03 | Leitz Ernst Gmbh | Kuevette zur mikroskopischen beobachtung und/oder optisch- elektrischen messung von in einer fluessigkeit suspendierten teilchen |
| NO144002C (no) * | 1979-04-10 | 1981-05-27 | Norsk Hydro S Inst For Kreftfo | Anordning for anvendelse ved vaeskestroemsfotometri |
| US4408877A (en) * | 1979-04-10 | 1983-10-11 | Ernst Leitz Wetzlar Gmbh | Device for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer |
| NO145176C (no) * | 1979-11-23 | 1982-01-27 | Norsk Hydros Inst For Kreftfor | Anordning ved vaeskestroemsfotometer. |
-
1985
- 1985-07-10 NO NO852761A patent/NO156916C/no unknown
-
1986
- 1986-07-10 DE DE8686904422T patent/DE3663744D1/de not_active Expired
- 1986-07-10 JP JP61503776A patent/JPS62503192A/ja active Granted
- 1986-07-10 WO PCT/NO1986/000050 patent/WO1987000282A1/en not_active Ceased
- 1986-07-10 US US07/036,675 patent/US4737025A/en not_active Expired - Fee Related
- 1986-07-10 AT AT86904422T patent/ATE43721T1/de not_active IP Right Cessation
- 1986-07-10 EP EP86904422A patent/EP0229814B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO852761L (no) | 1987-01-12 |
| US4737025A (en) | 1988-04-12 |
| NO156916B (no) | 1987-09-07 |
| EP0229814A1 (en) | 1987-07-29 |
| NO156916C (no) | 1987-12-16 |
| DE3663744D1 (en) | 1989-07-06 |
| WO1987000282A1 (en) | 1987-01-15 |
| ATE43721T1 (de) | 1989-06-15 |
| EP0229814B1 (en) | 1989-05-31 |
| JPS62503192A (ja) | 1987-12-17 |
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