JPH034555B2 - - Google Patents

Info

Publication number
JPH034555B2
JPH034555B2 JP55047012A JP4701280A JPH034555B2 JP H034555 B2 JPH034555 B2 JP H034555B2 JP 55047012 A JP55047012 A JP 55047012A JP 4701280 A JP4701280 A JP 4701280A JP H034555 B2 JPH034555 B2 JP H034555B2
Authority
JP
Japan
Prior art keywords
adca
mol
cephadroxil
hydrate
cooled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP55047012A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5683492A (en
Inventor
Fuarushiani Maruko
Burotsugi Renaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dobfar SpA
Original Assignee
Dobfar SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dobfar SpA filed Critical Dobfar SpA
Publication of JPS5683492A publication Critical patent/JPS5683492A/ja
Publication of JPH034555B2 publication Critical patent/JPH034555B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
JP4701280A 1979-12-07 1980-04-11 Manufacture of 77aminodesacetoxycephalosporanic acid derivative Granted JPS5683492A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT27962/79A IT1126544B (it) 1979-12-07 1979-12-07 Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico

Publications (2)

Publication Number Publication Date
JPS5683492A JPS5683492A (en) 1981-07-08
JPH034555B2 true JPH034555B2 (en, 2012) 1991-01-23

Family

ID=11222690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4701280A Granted JPS5683492A (en) 1979-12-07 1980-04-11 Manufacture of 77aminodesacetoxycephalosporanic acid derivative

Country Status (10)

Country Link
US (1) US4299955A (en, 2012)
JP (1) JPS5683492A (en, 2012)
KR (1) KR830002454B1 (en, 2012)
CH (1) CH645647A5 (en, 2012)
DE (1) DE3012669A1 (en, 2012)
FR (1) FR2470771A1 (en, 2012)
GB (1) GB2064511B (en, 2012)
IT (1) IT1126544B (en, 2012)
NL (1) NL191239C (en, 2012)
YU (1) YU125780A (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
ES488286A0 (es) * 1980-02-05 1980-12-16 Liofilizaciones Esterilizacion Procedimiento para la obtencion de una sal soluble en agua de cefadroxilo
YU44832B (en) * 1981-08-03 1991-04-30 Pliva Pharm & Chem Works Process for preparing semisynthetic cephalosporins
HU221200B1 (en) * 1990-01-22 2002-08-28 Biochemie Gmbh Process for producing beta-lactames
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
US5908929A (en) * 1996-12-05 1999-06-01 Vitara Chemicals Limited Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
GB1327270A (en) 1970-10-26 1973-08-22 Osaka Univeristy President Of Acylation of 6-aminopenicillanic acid and 7-aminocephalospor anic acids
BE793191A (fr) * 1971-12-28 1973-06-22 Toyama Chemical Co Ltd Procede pour produire des acides 7-acylamido-3-cephem-4- carboxyliques
YU39709B (en) * 1972-09-15 1985-04-30 Bristol Myers Co Process for producing cephalosporin
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
US3965098A (en) 1972-11-29 1976-06-22 American Home Products Corporation Intermediates for preparing cephalosporins and methods of production
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
GB1473090A (en, 2012) * 1973-07-19 1977-05-11
ES419149A1 (es) * 1973-09-28 1976-07-01 Fener S L Lab Procedimiento para la obtencion de a-amino-penicilinas y cefalosporinas.
NL166831C (nl) * 1974-07-17 1981-09-15 Nederlanden Staat Inrichting voor het bewaken van de kwaliteit van straalverbindingen.
JPS5129489A (en) * 1974-08-30 1976-03-12 Kanebo Ltd Penishirinrui oyobi sefuarosuhorinrui no seizoho
JPS51105091A (en) * 1975-03-12 1976-09-17 Sangyo Kagaku Kenkyu Kyokai Aminoashirukano kairyohoho
JPS5283490A (en) * 1975-12-30 1977-07-12 Tokyo Tanabe Co Process for preparing 77glycylamino cephlospoline derivatives
GB1532682A (en) 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
AT363594B (de) * 1978-02-01 1981-08-10 Biochemie Gmbh Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure

Also Published As

Publication number Publication date
CH645647A5 (it) 1984-10-15
IT7927962A0 (it) 1979-12-07
DE3012669A1 (de) 1981-06-11
IT1126544B (it) 1986-05-21
KR830002454B1 (ko) 1983-10-26
US4299955A (en) 1981-11-10
FR2470771B1 (en, 2012) 1984-04-27
YU125780A (en) 1983-04-30
DE3012669C2 (en, 2012) 1991-05-08
FR2470771A1 (fr) 1981-06-12
NL191239C (nl) 1995-04-03
GB2064511A (en) 1981-06-17
NL8006367A (nl) 1981-07-01
GB2064511B (en) 1983-06-22
NL191239B (nl) 1994-11-01
JPS5683492A (en) 1981-07-08
KR830002774A (ko) 1983-05-30

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