JPH03191963A - リン酸カルシウム質多孔体骨補填材 - Google Patents
リン酸カルシウム質多孔体骨補填材Info
- Publication number
- JPH03191963A JPH03191963A JP1331223A JP33122389A JPH03191963A JP H03191963 A JPH03191963 A JP H03191963A JP 1331223 A JP1331223 A JP 1331223A JP 33122389 A JP33122389 A JP 33122389A JP H03191963 A JPH03191963 A JP H03191963A
- Authority
- JP
- Japan
- Prior art keywords
- pores
- calcium phosphate
- porous body
- porous
- porosity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000001506 calcium phosphate Substances 0.000 title claims abstract description 29
- 229910000389 calcium phosphate Inorganic materials 0.000 title claims abstract description 28
- 235000011010 calcium phosphates Nutrition 0.000 title claims abstract description 28
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 title claims abstract description 23
- 210000000988 bone and bone Anatomy 0.000 title abstract description 40
- 239000011148 porous material Substances 0.000 claims abstract description 71
- 210000000963 osteoblast Anatomy 0.000 claims abstract description 9
- 239000011800 void material Substances 0.000 abstract description 9
- 230000015572 biosynthetic process Effects 0.000 abstract description 4
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 description 23
- 239000002002 slurry Substances 0.000 description 13
- 238000010438 heat treatment Methods 0.000 description 8
- 239000011575 calcium Substances 0.000 description 6
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 6
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 6
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 5
- -1 calcium phosphate compound Chemical class 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 239000004604 Blowing Agent Substances 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 239000000316 bone substitute Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 239000013354 porous framework Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1331223A JPH03191963A (ja) | 1989-12-22 | 1989-12-22 | リン酸カルシウム質多孔体骨補填材 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1331223A JPH03191963A (ja) | 1989-12-22 | 1989-12-22 | リン酸カルシウム質多孔体骨補填材 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH03191963A true JPH03191963A (ja) | 1991-08-21 |
| JPH0534020B2 JPH0534020B2 (enrdf_load_stackoverflow) | 1993-05-21 |
Family
ID=18241273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1331223A Granted JPH03191963A (ja) | 1989-12-22 | 1989-12-22 | リン酸カルシウム質多孔体骨補填材 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH03191963A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005023325A1 (ja) * | 2003-08-27 | 2005-03-17 | Pentax Corporation | 微細骨粉を含浸させた生体適合性材料からなる構造体及びその製造方法 |
| JP2008513161A (ja) * | 2004-09-21 | 2008-05-01 | トーマス ジョセフ ラリー， | 多目的生体材料組成物 |
| US10286102B2 (en) | 2010-05-11 | 2019-05-14 | Howmedica Osteonics Corp | Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods |
| US12343444B2 (en) | 2021-08-16 | 2025-07-01 | Bone Solutions, Inc. | Structural implant to prevent bone defects |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5812649A (ja) * | 1981-07-15 | 1983-01-24 | 三菱鉱業セメント株式会社 | 骨欠損部及び空隙部充てん材 |
| JPS6016879A (ja) * | 1983-07-09 | 1985-01-28 | 住友セメント株式会社 | 多孔質セラミツク材料 |
| JPS60142857A (ja) * | 1983-12-29 | 1985-07-29 | 住友セメント株式会社 | 骨セメント組成物 |
| JPS619858A (ja) * | 1984-06-23 | 1986-01-17 | Terada Denki Seisakusho:Kk | 磁気テ−プ装置のオ−トリバ−ス機構 |
| JPS6222655A (ja) * | 1985-07-22 | 1987-01-30 | 株式会社イナックス | 歯・骨補填用アパタイト系焼結体およびその製法 |
| JPS63294864A (ja) * | 1987-10-23 | 1988-12-01 | Tdk Corp | 人工骨材料の製造方法 |
| JPS6449501A (en) * | 1987-08-18 | 1989-02-27 | Japan Synthetic Rubber Co Ltd | Production of shoe sole |
| JPH01314572A (ja) * | 1988-06-15 | 1989-12-19 | Asahi Optical Co Ltd | セラミックス多孔体の製造方法 |
-
1989
- 1989-12-22 JP JP1331223A patent/JPH03191963A/ja active Granted
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5812649A (ja) * | 1981-07-15 | 1983-01-24 | 三菱鉱業セメント株式会社 | 骨欠損部及び空隙部充てん材 |
| JPS6016879A (ja) * | 1983-07-09 | 1985-01-28 | 住友セメント株式会社 | 多孔質セラミツク材料 |
| JPS60142857A (ja) * | 1983-12-29 | 1985-07-29 | 住友セメント株式会社 | 骨セメント組成物 |
| JPS619858A (ja) * | 1984-06-23 | 1986-01-17 | Terada Denki Seisakusho:Kk | 磁気テ−プ装置のオ−トリバ−ス機構 |
| JPS6222655A (ja) * | 1985-07-22 | 1987-01-30 | 株式会社イナックス | 歯・骨補填用アパタイト系焼結体およびその製法 |
| JPS6449501A (en) * | 1987-08-18 | 1989-02-27 | Japan Synthetic Rubber Co Ltd | Production of shoe sole |
| JPS63294864A (ja) * | 1987-10-23 | 1988-12-01 | Tdk Corp | 人工骨材料の製造方法 |
| JPH01314572A (ja) * | 1988-06-15 | 1989-12-19 | Asahi Optical Co Ltd | セラミックス多孔体の製造方法 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005023325A1 (ja) * | 2003-08-27 | 2005-03-17 | Pentax Corporation | 微細骨粉を含浸させた生体適合性材料からなる構造体及びその製造方法 |
| JP2008513161A (ja) * | 2004-09-21 | 2008-05-01 | トーマス ジョセフ ラリー， | 多目的生体材料組成物 |
| US10286102B2 (en) | 2010-05-11 | 2019-05-14 | Howmedica Osteonics Corp | Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods |
| US12343444B2 (en) | 2021-08-16 | 2025-07-01 | Bone Solutions, Inc. | Structural implant to prevent bone defects |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0534020B2 (enrdf_load_stackoverflow) | 1993-05-21 |
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Legal Events
| Date | Code | Title | Description |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
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| R350 | Written notification of registration of transfer |
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| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090521 Year of fee payment: 16 |
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| LAPS | Cancellation because of no payment of annual fees |