JPH0318492B2 - - Google Patents
Info
- Publication number
- JPH0318492B2 JPH0318492B2 JP58107634A JP10763483A JPH0318492B2 JP H0318492 B2 JPH0318492 B2 JP H0318492B2 JP 58107634 A JP58107634 A JP 58107634A JP 10763483 A JP10763483 A JP 10763483A JP H0318492 B2 JPH0318492 B2 JP H0318492B2
- Authority
- JP
- Japan
- Prior art keywords
- weight
- hollow fiber
- fiber membrane
- spinning
- albumin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012510 hollow fiber Substances 0.000 claims description 43
- 239000012528 membrane Substances 0.000 claims description 33
- 238000009987 spinning Methods 0.000 claims description 19
- 229920002301 cellulose acetate Polymers 0.000 claims description 17
- 239000011550 stock solution Substances 0.000 claims description 13
- 238000004519 manufacturing process Methods 0.000 claims description 9
- -1 nitrogen-containing compound Chemical class 0.000 claims description 9
- 229920002678 cellulose Polymers 0.000 claims description 8
- 238000002166 wet spinning Methods 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 7
- 150000002576 ketones Chemical class 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 5
- 102000007562 Serum Albumin Human genes 0.000 claims description 4
- 108010071390 Serum Albumin Proteins 0.000 claims description 4
- 239000012046 mixed solvent Substances 0.000 claims description 3
- 239000011148 porous material Substances 0.000 description 20
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 18
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 17
- 102000009027 Albumins Human genes 0.000 description 14
- 108010088751 Albumins Proteins 0.000 description 14
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 12
- 238000000034 method Methods 0.000 description 12
- 239000007788 liquid Substances 0.000 description 9
- 230000001112 coagulating effect Effects 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 7
- 239000001110 calcium chloride Substances 0.000 description 7
- 229910001628 calcium chloride Inorganic materials 0.000 description 7
- 235000011148 calcium chloride Nutrition 0.000 description 7
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
- 230000035699 permeability Effects 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 6
- 229960002713 calcium chloride Drugs 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000021736 acetylation Effects 0.000 description 4
- 238000006640 acetylation reaction Methods 0.000 description 4
- 235000013877 carbamide Nutrition 0.000 description 4
- JBKVHLHDHHXQEQ-UHFFFAOYSA-N epsilon-caprolactam Chemical compound O=C1CCCCCN1 JBKVHLHDHHXQEQ-UHFFFAOYSA-N 0.000 description 4
- NIQQIJXGUZVEBB-UHFFFAOYSA-N methanol;propan-2-one Chemical compound OC.CC(C)=O NIQQIJXGUZVEBB-UHFFFAOYSA-N 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 3
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 102000018358 immunoglobulin Human genes 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 239000000020 Nitrocellulose Substances 0.000 description 2
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- LLSDKQJKOVVTOJ-UHFFFAOYSA-L calcium chloride dihydrate Chemical compound O.O.[Cl-].[Cl-].[Ca+2] LLSDKQJKOVVTOJ-UHFFFAOYSA-L 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- AVQQQNCBBIEMEU-UHFFFAOYSA-N 1,1,3,3-tetramethylurea Chemical compound CN(C)C(=O)N(C)C AVQQQNCBBIEMEU-UHFFFAOYSA-N 0.000 description 1
- TUMNHQRORINJKE-UHFFFAOYSA-N 1,1-diethylurea Chemical compound CCN(CC)C(N)=O TUMNHQRORINJKE-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical group CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- 229920002284 Cellulose triacetate Polymers 0.000 description 1
- MGJKQDOBUOMPEZ-UHFFFAOYSA-N N,N'-dimethylurea Chemical compound CNC(=O)NC MGJKQDOBUOMPEZ-UHFFFAOYSA-N 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 229940052299 calcium chloride dihydrate Drugs 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 150000003950 cyclic amides Chemical class 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- XUWHAWMETYGRKB-UHFFFAOYSA-N piperidin-2-one Chemical compound O=C1CCCCN1 XUWHAWMETYGRKB-UHFFFAOYSA-N 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- QLNJFJADRCOGBJ-UHFFFAOYSA-N propionamide Chemical compound CCC(N)=O QLNJFJADRCOGBJ-UHFFFAOYSA-N 0.000 description 1
- 229940080818 propionamide Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Artificial Filaments (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10763483A JPS60806A (ja) | 1983-06-17 | 1983-06-17 | 血漿アルブミン選択透過性中空糸膜の製造法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10763483A JPS60806A (ja) | 1983-06-17 | 1983-06-17 | 血漿アルブミン選択透過性中空糸膜の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60806A JPS60806A (ja) | 1985-01-05 |
JPH0318492B2 true JPH0318492B2 (de) | 1991-03-12 |
Family
ID=14464158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10763483A Granted JPS60806A (ja) | 1983-06-17 | 1983-06-17 | 血漿アルブミン選択透過性中空糸膜の製造法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS60806A (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0201604B1 (de) * | 1984-10-30 | 1991-08-28 | Teijin Limited | Hohlfasermembran mit selektiver durchlässigkeit, deren herstellung und verfahren zur scheidung von plasmakomponenten sowie plasmakomponentabscheider |
US4744932A (en) * | 1985-05-31 | 1988-05-17 | Celanese Corporation | Process for forming a skinless hollow fiber of a cellulose ester |
JPS6277325A (ja) * | 1985-09-30 | 1987-04-09 | Asahi Chem Ind Co Ltd | アルブミンの膜分離方法 |
JP2006083292A (ja) * | 2004-09-16 | 2006-03-30 | Fuji Photo Film Co Ltd | 微細多孔性膜の安定製造方法および核酸分離精製方法におけるその使用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5411322A (en) * | 1977-06-29 | 1979-01-27 | Asahi Chem Ind Co Ltd | Hollow cellulose fibers and their production |
JPS5643415A (en) * | 1979-09-13 | 1981-04-22 | Nippon Zeon Co Ltd | Production of hollow fiber |
JPS56134209A (en) * | 1980-02-23 | 1981-10-20 | Akzo Nv | Film comprising cellulose ester and method |
JPS57210010A (en) * | 1981-06-19 | 1982-12-23 | Teijin Ltd | Production of porous hollow fiber membrane |
-
1983
- 1983-06-17 JP JP10763483A patent/JPS60806A/ja active Granted
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5411322A (en) * | 1977-06-29 | 1979-01-27 | Asahi Chem Ind Co Ltd | Hollow cellulose fibers and their production |
JPS5643415A (en) * | 1979-09-13 | 1981-04-22 | Nippon Zeon Co Ltd | Production of hollow fiber |
JPS56134209A (en) * | 1980-02-23 | 1981-10-20 | Akzo Nv | Film comprising cellulose ester and method |
JPS57210010A (en) * | 1981-06-19 | 1982-12-23 | Teijin Ltd | Production of porous hollow fiber membrane |
Also Published As
Publication number | Publication date |
---|---|
JPS60806A (ja) | 1985-01-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0201604B1 (de) | Hohlfasermembran mit selektiver durchlässigkeit, deren herstellung und verfahren zur scheidung von plasmakomponenten sowie plasmakomponentabscheider | |
JP3248632B2 (ja) | 芳香族重縮合物の非対称半透膜、それらの製造方法およびそれらの使用 | |
EP0012630B1 (de) | Verfahren zur Herstellung einer selektiv durchlässigen Membran des Zelluloseazetat-Typs, so hergestellte selektiv durchlässige Membran und Anwendung einer derartigen Membran in einer künstlichen Niere | |
AU672856B2 (en) | High flux hollow fiber membrane | |
JP2542572B2 (ja) | 中空繊維 | |
JPH0318492B2 (de) | ||
JPS5938805B2 (ja) | 選択透過性を有する半透膜の製法 | |
CA2093619A1 (en) | Hollow fiber membrane for blood purification | |
JPH053335B2 (de) | ||
JPH10216489A (ja) | セルロース中空糸膜およびその製造方法 | |
JP3020016B2 (ja) | 中空糸膜 | |
JP3424807B2 (ja) | 中空糸膜 | |
JPH0120245B2 (de) | ||
JPH0375205B2 (de) | ||
JP4381022B2 (ja) | 中空糸型血液浄化膜 | |
JP3205268B2 (ja) | 選択透過性中空糸膜の製造方法 | |
JP2000107577A (ja) | 選択透過性中空糸膜の製造方法 | |
JP2501933B2 (ja) | 銅アンモニア法再生セルロ―ス中空糸およびその製造方法 | |
JPH0712421B2 (ja) | ポリスルホン製中空糸膜の製造法 | |
JP2000210544A (ja) | 半透膜の製造方法 | |
JPH0566169B2 (de) | ||
JPS5841883B2 (ja) | 血漿分離膜とその製法 | |
JP2818355B2 (ja) | 中空糸膜の製造方法 | |
JP3205267B2 (ja) | 選択透過性中空糸膜の製造方法 | |
JPS60193504A (ja) | 透析用中空繊維膜 |