JPH0310630B2 - - Google Patents

Info

Publication number
JPH0310630B2
JPH0310630B2 JP57160943A JP16094382A JPH0310630B2 JP H0310630 B2 JPH0310630 B2 JP H0310630B2 JP 57160943 A JP57160943 A JP 57160943A JP 16094382 A JP16094382 A JP 16094382A JP H0310630 B2 JPH0310630 B2 JP H0310630B2
Authority
JP
Japan
Prior art keywords
camptothecin
mmol
tetrahydrocamptothecin
chloroform
under reduced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57160943A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5951287A (ja
Inventor
Sada Myasaka
Seigo Sawada
Kenichiro Nogata
Masahiko Mutai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Priority to JP16094382A priority Critical patent/JPS5951287A/ja
Publication of JPS5951287A publication Critical patent/JPS5951287A/ja
Publication of JPH0310630B2 publication Critical patent/JPH0310630B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP16094382A 1982-09-17 1982-09-17 新規なカンプトテシン誘導体 Granted JPS5951287A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16094382A JPS5951287A (ja) 1982-09-17 1982-09-17 新規なカンプトテシン誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16094382A JPS5951287A (ja) 1982-09-17 1982-09-17 新規なカンプトテシン誘導体

Publications (2)

Publication Number Publication Date
JPS5951287A JPS5951287A (ja) 1984-03-24
JPH0310630B2 true JPH0310630B2 (cs) 1991-02-14

Family

ID=15725567

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16094382A Granted JPS5951287A (ja) 1982-09-17 1982-09-17 新規なカンプトテシン誘導体

Country Status (1)

Country Link
JP (1) JPS5951287A (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62129960U (cs) * 1986-02-13 1987-08-17
JPS62129961U (cs) * 1986-02-13 1987-08-17
US5053512A (en) * 1987-04-14 1991-10-01 Research Triangle Institute Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives
US5106742A (en) * 1987-03-31 1992-04-21 Wall Monroe E Camptothecin analogs as potent inhibitors of topoisomerase I
US5122526A (en) * 1987-03-31 1992-06-16 Research Triangle Institute Camptothecin and analogs thereof and pharmaceutical compositions and method using them
US5227380A (en) * 1987-03-31 1993-07-13 Research Triangle Institute Pharmaceutical compositions and methods employing camptothecins
US4981968A (en) * 1987-03-31 1991-01-01 Research Triangle Institute Synthesis of camptothecin and analogs thereof
US5364858A (en) * 1987-03-31 1994-11-15 Research Triangle Institute Camptothecin analogs as potent inhibitors of topoisomerase I
US5180722A (en) * 1987-04-14 1993-01-19 Research Triangle Institute 10,11-methylenedioxy-20(RS)-camptothecin and 10,11-methylenedioxy-20(S)-camptothecin analogs
US5122606A (en) * 1987-04-14 1992-06-16 Research Triangle Institute 10,11-methylenedioxy camptothecins
US5340817A (en) * 1987-04-14 1994-08-23 Research Triangle Institute Method of treating tumors with anti-tumor effective camptothecin compounds
US5049668A (en) * 1989-09-15 1991-09-17 Research Triangle Institute 10,11-methylenedioxy-20(RS)-camptothecin analogs
US5225404A (en) * 1989-11-06 1993-07-06 New York University Methods of treating colon tumors with tumor-inhibiting camptothecin compounds
US5552154A (en) * 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
US5447936A (en) * 1993-12-22 1995-09-05 Bionumerik Pharmaceuticals, Inc. Lactone stable formulation of 10-hydroxy 7-ethyl camptothecin and methods for uses thereof
US5468754A (en) * 1994-04-19 1995-11-21 Bionumerik Pharmaceuticals, Inc. 11,7 substituted camptothecin derivatives and formulations of 11,7 substituted camptothecin derivatives and methods for uses thereof
US5646159A (en) * 1994-07-20 1997-07-08 Research Triangle Institute Water-soluble esters of camptothecin compounds
JPH0873461A (ja) * 1994-09-06 1996-03-19 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体、その製造法および抗腫瘍剤
US5614529A (en) * 1994-09-22 1997-03-25 Research Triangle Institute Inhibition of plasmodia parasites by camptothecin compounds
JP4094710B2 (ja) 1997-11-06 2008-06-04 株式会社ヤクルト本社 新規なカンプトテシン誘導体
IL161478A0 (en) 2001-10-25 2004-09-27 Takeda Chemical Industries Ltd Quinoline compound

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS *

Also Published As

Publication number Publication date
JPS5951287A (ja) 1984-03-24

Similar Documents

Publication Publication Date Title
JPH0310630B2 (cs)
JPH0312070B2 (cs)
JP2848958B2 (ja) 水溶性カンプトテシン類似体、方法および手段
JPS6232749B2 (cs)
GB2056973A (en) Camptothecin derivatives useful as antitumour agents
JPH085879B2 (ja) ２−ハロゲン化エルゴリン誘導体の製法
JP4559730B2 (ja) １４−ヒドロキシノルモルフィノン誘導体の調製方法。
JPS6150985A (ja) 新規なカンプトテシン誘導体
JPH029032B2 (cs)
JPH0434999B2 (cs)
JPS6247873B2 (cs)
JPS6247193B2 (cs)
JPH0312069B2 (cs)
JPS60197687A (ja) インドロフエナントリジン類
JPS6247194B2 (cs)
JPS636070B2 (cs)
JPS636072B2 (cs)
JP2024526159A (ja) Ｃｙｐ１１ａ１阻害薬及びその中間体を調製する方法
JP4477510B2 (ja) １０−ヒドロキシ−４−（ｓ）カンプトテンシンからトポテカンを調製する方法
JP4498923B2 (ja) イミダゾ（１，２−ａ）ピリジン−３−アセトアミド類の調製方法
WO2001070747A1 (fr) Procede de production de camptothecine
JPS636071B2 (cs)
JPS6411636B2 (cs)
EP0207336A2 (en) Nitro derivatives of vinblastine-type bis-indoles, a process for preparing same and pharmaceutical compositions containing them
JPS61286390A (ja) ２−ブロモ−α−エルゴクリプチンの製造方法