JPH0144198B2 - - Google Patents

Info

Publication number
JPH0144198B2
JPH0144198B2 JP57060381A JP6038182A JPH0144198B2 JP H0144198 B2 JPH0144198 B2 JP H0144198B2 JP 57060381 A JP57060381 A JP 57060381A JP 6038182 A JP6038182 A JP 6038182A JP H0144198 B2 JPH0144198 B2 JP H0144198B2
Authority
JP
Japan
Prior art keywords
angiotensin
medium
converting enzyme
water
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP57060381A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58177920A (ja
Inventor
Yasuhito Kido
Tsutomu Yoshida
Toshinari Hamakado
Masami Abu
Takahiro Harada
Yoshinobu Motoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio Inc filed Critical Fujirebio Inc
Priority to JP57060381A priority Critical patent/JPS58177920A/ja
Priority to US06/482,356 priority patent/US4526866A/en
Publication of JPS58177920A publication Critical patent/JPS58177920A/ja
Publication of JPH0144198B2 publication Critical patent/JPH0144198B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C07K4/04—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP57060381A 1982-04-13 1982-04-13 酵素阻害剤ｉｓ８３ Granted JPS58177920A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP57060381A JPS58177920A (ja) 1982-04-13 1982-04-13 酵素阻害剤ｉｓ８３
US06/482,356 US4526866A (en) 1982-04-13 1983-04-05 Angiotensin I-converting enzyme inhibitor and preparation of the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57060381A JPS58177920A (ja) 1982-04-13 1982-04-13 酵素阻害剤ｉｓ８３

Publications (2)

Publication Number Publication Date
JPS58177920A JPS58177920A (ja) 1983-10-18
JPH0144198B2 true JPH0144198B2 (en, 2012) 1989-09-26

Family

ID=13140504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57060381A Granted JPS58177920A (ja) 1982-04-13 1982-04-13 酵素阻害剤ｉｓ８３

Country Status (2)

Country Link
US (1) US4526866A (en, 2012)
JP (1) JPS58177920A (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5314807A (en) * 1991-03-29 1994-05-24 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Method for producing an angiotensin converting enzyme inhibitor-containing composition
JP3093378B2 (ja) * 1991-10-17 2000-10-03 日本合成化学工業株式会社 アンギオテンシン変換酵素阻害剤含有組成物の製造方法
JPH05279374A (ja) * 1992-03-31 1993-10-26 Sawao Murao スイダトレスチン及びその製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404282A (en) * 1982-08-19 1983-09-13 Eli Lilly And Company Process for enzyme inhibitor

Also Published As

Publication number Publication date
JPS58177920A (ja) 1983-10-18
US4526866A (en) 1985-07-02

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