JPH01175909A - Germicidal composition - Google Patents

Abstract

PURPOSE:To obtain an agricultural and horticultural germicidal composition, containing a specific carbamoyl based germicide and prumycin as active ingredients and capable of exhibiting remarkable effects on germs resistant to existing agricultural chemicals without exerting bad influences, such as phytotoxicity, on plant bodies. CONSTITUTION:A germicidal composition, obtained by blending (A) 1- isopropylcarbamoyl-3-(3,5-dichlorophenyl)hydantoin with (B) 4-N-D-alanyl-2,4- diamino-2,4-dideoxyarabinose (prumycin) as active ingredients at 20:1-1:1, preferably 16:1-2:1 weight ratio so as to provide 0.1-99.9wt.%, preferably 0.2-80wt.% total amount of the ingredients (A) and (B) and capable of exhibiting high controlling effects especially by foliar spraying, effective against even chemical-resistant germs, having unexpected high synergistic effects and useful as an agricultural and horticultural germicide in paddy field, farmland or orchard, etc.

Description

Detailed Description of the Invention [Field of Industrial Application] The present invention relates to a fungicidal composition containing a carbamoyl fungicide and purmycin as active ingredients. [Prior Art] 1-Inpropylcarbamoyl-3-(3,5-dichlorophenyl)hydantoin (Compound A), which is one of the active ingredients of the composition of the present invention, can be used as an agricultural and horticultural agent. It shows excellent control effects against various pathogenic bacteria that parasitize crops, and is currently widely used as a fungicide for agricultural and horticultural purposes. The control effect has decreased, and in some areas, no control effect has been observed at all.On the other hand, purmycin has been shown to be effective in J Antibiotics 24:90.
It is a known antibiotic described in 0-901 (1971),
It was manufactured by Japanese Patent Publication No. 57-8718 and is known to be effective against various agricultural and horticultural crop diseases (Japanese Patent Publication No. 57-8718).
33128).

[Problem to be solved by the invention] The emergence of drug-resistant bacteria to conventional fungicides has become a very serious problem in the control of agricultural and horticultural crop diseases. The aim is to provide a useful agricultural and horticultural fungicide that compensates for the drawbacks of conventional fungicides, is highly effective against bacteria resistant to existing pesticides, and does not have any adverse effects on plants, such as phytotoxicity.

When the fungicidal composition of the present invention is used as a fungicide for agriculture and horticulture, depending on the purpose of use, it is generally used in the field of agrochemical manufacturing, either as is or with a mixture of pesticide adjuvants to enhance or stabilize the effect. Depending on the method, it can be used in the form of preparations such as powders, fine granules, granules, wettable powders, flowable preparations, and emulsions.

In actual use, these various formulations can be used directly or diluted with water to a desired concentration.

Preferably, the ratio is 1:1 to 2:1, and the ratio is 0.1 to 99.
9, preferably 0.2 to 80%, according to a usual formulation method.

Examples of the above agricultural chemical auxiliary agents include carriers (diluents) and other auxiliary agents such as spreading agents, emulsifiers, wetting agents, dispersants, fixing agents, and disintegrants.

Liquid carriers include aromatic hydrocarbons such as toluene and xylene, alcohols such as methanol, butanol, and glycol, ketones such as acetone, amides such as dimethylformamide, sulfoxides such as dimethyl sulfoxide, methylnaphthalenecyclohexane, and animal and vegetable oils. , fatty acids, fatty acid esters, etc.

Solid carriers include clay, kaolin, talc, diatomaceous earth,
Examples include silica, calcium carbonate, montmorillonite, bentonite, feldspar, quartz, alumina, and sawdust.

In addition, surfactants are usually used as emulsifiers or dispersants, such as anionic surfactants such as higher alcohol sodium sulfate, stearyltrimethylammonium chloride, polyoxyethylene alkylphenyl ether, lauryl betaine, and cationic surfactants. , nonionic surfactants, and amphoteric surfactants.

Spreading agents include polyoxyethylene nonylphenyl ether and polyoxyethylene lauryl ether, wetting agents include polyoxyethylene nonylphenyl and dialkyl sulfosuccinate, and fixing agents include carboxymethyl cellulose and polyvinyl alcohol. Examples of the agent include sodium acupuncture sulfonate and sodium lauryl sulfate.

Any of the preparations can be used not only alone, but also in combination with other agricultural and horticultural fungicides, insecticides, plant growth regulators, and acaricides.

When the fungicidal composition of the present invention is applied as a fungicide for agriculture and horticulture, the amount of application is usually 100% of the active ingredient per 10ares.
~300g is used, preferably 15-2oOg.

The application concentration is preferably in the range of 0.001 to 0.4% when diluted with water such as a wettable powder or liquid preparation.

In the case of powders, granules, fine granules, etc., the dosage may vary depending on the method of use, timing, and other conditions, and the concentration may be increased or decreased without sticking to the above range.

The present invention is effective for controlling the following crop diseases, but is not limited thereto.

Apple spot leaf disease (Alternaria mali)
) Monilinia mali
) Oyster powdery mildew 'C-point Puha 9 ribs kakicola
) 5clerotinia cinere
a) Botrytis cine
rea) Grape 5 powdery mildew (Uncinula nec
ator) Grape black rot (Elsione ampe)
lina) Sugar beet brown spot (Cercospora b)
ethicola) groundnut brown spot (4arachidic)
ola) wheat rust (Puccinia rec)
ondita) wheat yellow rust (Puccinia g
lumarum) Wheat black rust (Puccinia
glaminis) wheat naked smut
a) Wheat Gibbellero zeae Wheat snow rot Sclerotinia bor
alis) cucumber powdery mildew (Sphaeroth
eca fuliginia) Botrytis gray mold (
5clerotinia scler
otiorum) cucumber scab (Cladospo)
rium cucumerinum) Tomato Botrytis cinerea Tomato Sclerotinia sclerotiorum
) Botrytis cinerea
) Sclerotinia scler
otiorum) Green pepper gray mold (Chinese mold) Strawberry gray mold (Norimachi Mushi cineyu) Ri'? Allium gray rot (Botrytis alli) [Effects of the invention] The fungicidal composition of the present invention exhibits a high control effect particularly when sprayed on foliage, is effective against drug-resistant bacteria, and has an unexpectedly high synergistic effect. They discovered this and completed the present invention.

Next, examples of the cleaving agent as an agricultural and horticultural fungicide of the present invention will be specifically explained in more detail, but the types and mixing ratios of the pesticide adjuvant are not limited to these, and can be used in a wide range. be. Note that "parts" means "parts by weight."

Case example 1. Powder 4 parts of compound A, 1 part of purmycin, 46 parts of talc, and 49 parts of clay are mixed and ground to form a powder.

45 parts of phosphorus, 3 parts of higher alcohol sodium sulfate, and 2 parts of sodium lignin sulfonate are mixed and ground to prepare a wettable powder.

After mixing 35 parts of bentonite, 23 parts of bentonite, 30 parts of talc and 2 parts of disintegrant, 18 parts of water was added to evenly moisten, then extruded through an injection molding machine, granulated, and sized with a sizing machine. After that, it is dried to form granules with a particle size of 0.6 mm to 1 mm.

Formulation Example: 4 parts of fine granule Compound A, 6 parts of purmycin, 6 parts of polyvinyl alcohol, and 9 parts of clay are uniformly mixed and pulverized to form a thick powder. Separately, 80 parts of oil well-absorbing mineral coarse powder of 74 to 105 microns is placed in a suitable mixer, and 20 parts of water is added while rotating to moisten it, and the above-mentioned thick powder is added, coated, and dried to form fine granules.

A mixture of an alkylphenol ethylene oxide condensate and calcium alkylbenzene sulfonate (8:2) (17 parts) was mixed and dissolved therein to prepare an emulsion.

Liquid medicines are diluted with water and used as emulsions.

Next, it will be explained using experimental examples that the fungicidal composition of the present invention has excellent control effects against various agricultural and horticultural crop diseases.

Experimental example 1. Green bean gray mold control test (drug window fungus) Example 2 of fission agent. The hydrating agent exploded in accordance with
trytis cinerea) was allowed to develop in a greenhouse, and the lesion diameter was examined after 72 hours to calculate the control value.

The results are shown in Table 1. The control value was calculated as follows.

Table 1 Experimental example 2. Green bean gray mold control test (drug-resistant bacteria) A dicarboximide-resistant bacterium was used as the gray mold fungus.

Other test methods are Experimental Example 1. According to.

The results are shown in Table 2.

Table 2 Patent applicant: Nippon Kayaku Co., Ltd.

Claims (1)

[Claims] (1) 1-isopropylcarbamoyl-3-(3,5-
An agricultural and horticultural fungicidal composition containing as active ingredients hydantoin (dichlorophenyl) and 4-N-D-alanyl-2,4-diamino-2,4-dideoxyarabinose (purmycin).