JPH01104267A - 医療用軟質塩化ビニル系樹脂組成物および医療用具 - Google Patents
医療用軟質塩化ビニル系樹脂組成物および医療用具Info
- Publication number
- JPH01104267A JPH01104267A JP62261649A JP26164987A JPH01104267A JP H01104267 A JPH01104267 A JP H01104267A JP 62261649 A JP62261649 A JP 62261649A JP 26164987 A JP26164987 A JP 26164987A JP H01104267 A JPH01104267 A JP H01104267A
- Authority
- JP
- Japan
- Prior art keywords
- ether
- vinyl chloride
- chloride resin
- resin composition
- medical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 239000011342 resin composition Substances 0.000 title claims abstract description 67
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims abstract description 130
- -1 ether compound Chemical class 0.000 claims abstract description 64
- 210000004369 blood Anatomy 0.000 claims abstract description 60
- 239000008280 blood Substances 0.000 claims abstract description 60
- 239000004014 plasticizer Substances 0.000 claims abstract description 50
- 229920005989 resin Polymers 0.000 claims abstract description 22
- 239000011347 resin Substances 0.000 claims abstract description 22
- 239000000126 substance Substances 0.000 claims abstract description 6
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 25
- 239000001301 oxygen Substances 0.000 claims description 25
- 229910052760 oxygen Inorganic materials 0.000 claims description 25
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 23
- 125000001033 ether group Chemical group 0.000 claims description 22
- 125000004432 carbon atom Chemical group C* 0.000 claims description 19
- 235000011187 glycerol Nutrition 0.000 claims description 12
- PGIBJVOPLXHHGS-UHFFFAOYSA-N Di-n-decyl phthalate Chemical group CCCCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCCCC PGIBJVOPLXHHGS-UHFFFAOYSA-N 0.000 claims description 10
- 238000010828 elution Methods 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 125000005591 trimellitate group Chemical group 0.000 claims description 6
- JNXDCMUUZNIWPQ-UHFFFAOYSA-N trioctyl benzene-1,2,4-tricarboxylate Chemical group CCCCCCCCOC(=O)C1=CC=C(C(=O)OCCCCCCCC)C(C(=O)OCCCCCCCC)=C1 JNXDCMUUZNIWPQ-UHFFFAOYSA-N 0.000 claims description 5
- 210000003743 erythrocyte Anatomy 0.000 abstract description 17
- 206010018910 Haemolysis Diseases 0.000 abstract description 16
- 230000008588 hemolysis Effects 0.000 abstract description 16
- 230000001681 protective effect Effects 0.000 abstract description 2
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- 238000005345 coagulation Methods 0.000 abstract 1
- 150000002430 hydrocarbons Chemical group 0.000 description 38
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 33
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 29
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 27
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 18
- 239000000203 mixture Substances 0.000 description 16
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 13
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 10
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 description 9
- 230000002401 inhibitory effect Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 150000002170 ethers Chemical class 0.000 description 6
- 238000000465 moulding Methods 0.000 description 6
- 210000004623 platelet-rich plasma Anatomy 0.000 description 6
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- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
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- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 3
- QGCFQTWMBUKZFW-UHFFFAOYSA-N 1-butoxy-16-methylheptadecane Chemical compound C(CCC)OCCCCCCCCCCCCCCCC(C)C QGCFQTWMBUKZFW-UHFFFAOYSA-N 0.000 description 2
- CMCBDXRRFKYBDG-UHFFFAOYSA-N 1-dodecoxydodecane Chemical compound CCCCCCCCCCCCOCCCCCCCCCCCC CMCBDXRRFKYBDG-UHFFFAOYSA-N 0.000 description 2
- HDSGGLDPANXUOY-UHFFFAOYSA-N 16-methyl-1-propan-2-yloxyheptadecane Chemical compound CC(C)CCCCCCCCCCCCCCCOC(C)C HDSGGLDPANXUOY-UHFFFAOYSA-N 0.000 description 2
- SZNYYWIUQFZLLT-UHFFFAOYSA-N 2-methyl-1-(2-methylpropoxy)propane Chemical compound CC(C)COCC(C)C SZNYYWIUQFZLLT-UHFFFAOYSA-N 0.000 description 2
- QRIIMZADASNLNI-UHFFFAOYSA-N 3-[2-(2-ethylhexoxy)ethoxymethyl]heptane Chemical compound CCCCC(CC)COCCOCC(CC)CCCC QRIIMZADASNLNI-UHFFFAOYSA-N 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 229920001944 Plastisol Polymers 0.000 description 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 150000002431 hydrogen Chemical class 0.000 description 2
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000004999 plastisol Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- BKICBCVRTYZWEG-UHFFFAOYSA-N 1,2,3-tri(propan-2-yloxy)propane Chemical compound CC(C)OCC(OC(C)C)COC(C)C BKICBCVRTYZWEG-UHFFFAOYSA-N 0.000 description 1
- PFCRCIZEIVMONQ-UHFFFAOYSA-N 1-(2-butoxypropoxy)-3-methylbutane Chemical compound C(CCC)OC(COCCC(C)C)C PFCRCIZEIVMONQ-UHFFFAOYSA-N 0.000 description 1
- CIDHFUQBCBSBRO-UHFFFAOYSA-N 1-[2,3-bis(2-methylpropoxy)propoxy]-2-methylpropane Chemical compound CC(C)COCC(OCC(C)C)COCC(C)C CIDHFUQBCBSBRO-UHFFFAOYSA-N 0.000 description 1
- FJUBOZROYNKIMV-UHFFFAOYSA-N 1-[2,3-bis(3-methylbutoxy)propoxy]-3-methylbutane Chemical compound CC(C)CCOCC(OCCC(C)C)COCCC(C)C FJUBOZROYNKIMV-UHFFFAOYSA-N 0.000 description 1
- NMLLTHLOSVNFMY-UHFFFAOYSA-N 1-butoxy-3-methylbutane Chemical compound CCCCOCCC(C)C NMLLTHLOSVNFMY-UHFFFAOYSA-N 0.000 description 1
- ZEMPKEQAKRGZGQ-AAKVHIHISA-N 2,3-bis[[(z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (z)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCCC(O)C\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CC(O)CCCCCC)COC(=O)CCCCCCC\C=C/CC(O)CCCCCC ZEMPKEQAKRGZGQ-AAKVHIHISA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 description 1
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical compound CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 1
- WDQMWEYDKDCEHT-UHFFFAOYSA-N 2-ethylhexyl 2-methylprop-2-enoate Chemical compound CCCCC(CC)COC(=O)C(C)=C WDQMWEYDKDCEHT-UHFFFAOYSA-N 0.000 description 1
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 description 1
- PEFIQBVQMPKANX-UHFFFAOYSA-N 3-(1,3-dibutoxypropan-2-yloxymethyl)heptane Chemical compound CCCCOCC(COCCCC)OCC(CC)CCCC PEFIQBVQMPKANX-UHFFFAOYSA-N 0.000 description 1
- JWSYJZKEPKDXHA-UHFFFAOYSA-N 3-(2,5-dimethylhexan-2-yloxy)propane-1,2-diol Chemical compound C(C)(C)CCC(C)(C)OCC(O)CO JWSYJZKEPKDXHA-UHFFFAOYSA-N 0.000 description 1
- YHCCCMIWRBJYHG-UHFFFAOYSA-N 3-(2-ethylhexoxymethyl)heptane Chemical compound CCCCC(CC)COCC(CC)CCCC YHCCCMIWRBJYHG-UHFFFAOYSA-N 0.000 description 1
- CBWPGKXHWQUERP-UHFFFAOYSA-N 3-(2-propan-2-yloxyethoxymethyl)heptane Chemical compound CCCCC(CC)COCCOC(C)C CBWPGKXHWQUERP-UHFFFAOYSA-N 0.000 description 1
- YUFABGKXHDCWNL-UHFFFAOYSA-N 3-(2-propan-2-yloxypropoxymethyl)heptane Chemical compound C(C)(C)OC(COCC(CCCC)CC)C YUFABGKXHDCWNL-UHFFFAOYSA-N 0.000 description 1
- AEQSRSXWZJFUTF-UHFFFAOYSA-N 3-(20-methylhenicosan-5-yloxy)propane-1,2-diol Chemical compound OCC(O)COC(CCCC)CCCCCCCCCCCCCCC(C)C AEQSRSXWZJFUTF-UHFFFAOYSA-N 0.000 description 1
- GQQHEKOOHGFEED-UHFFFAOYSA-N 3-(propan-2-yloxymethyl)heptane Chemical compound CCCCC(CC)COC(C)C GQQHEKOOHGFEED-UHFFFAOYSA-N 0.000 description 1
- NZXXOEAWMQEZPZ-UHFFFAOYSA-N 3-[2-(2-ethylhexoxy)propoxymethyl]heptane Chemical compound CCCCC(CC)COCC(C)OCC(CC)CCCC NZXXOEAWMQEZPZ-UHFFFAOYSA-N 0.000 description 1
- KDEPTIZYSPUNAD-UHFFFAOYSA-N 3-[2-[2-(2-ethylhexoxy)ethoxy]ethoxymethyl]heptane Chemical compound CCCCC(CC)COCCOCCOCC(CC)CCCC KDEPTIZYSPUNAD-UHFFFAOYSA-N 0.000 description 1
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- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Chemical compound CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 1
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- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
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- PUFGCEQWYLJYNJ-UHFFFAOYSA-N didodecyl benzene-1,2-dicarboxylate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCCCCCC PUFGCEQWYLJYNJ-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62261649A JPH01104267A (ja) | 1987-10-19 | 1987-10-19 | 医療用軟質塩化ビニル系樹脂組成物および医療用具 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62261649A JPH01104267A (ja) | 1987-10-19 | 1987-10-19 | 医療用軟質塩化ビニル系樹脂組成物および医療用具 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01104267A true JPH01104267A (ja) | 1989-04-21 |
| JPH0242503B2 JPH0242503B2 (zh) | 1990-09-25 |
Family
ID=17364839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62261649A Granted JPH01104267A (ja) | 1987-10-19 | 1987-10-19 | 医療用軟質塩化ビニル系樹脂組成物および医療用具 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01104267A (zh) |
-
1987
- 1987-10-19 JP JP62261649A patent/JPH01104267A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0242503B2 (zh) | 1990-09-25 |
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