JP7844766B2 - 抗特発性肺線維症薬ニンテダニブの結核を治療するための使用 - Google Patents

抗特発性肺線維症薬ニンテダニブの結核を治療するための使用

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Publication number
JP7844766B2
JP7844766B2 JP2024553621A JP2024553621A JP7844766B2 JP 7844766 B2 JP7844766 B2 JP 7844766B2 JP 2024553621 A JP2024553621 A JP 2024553621A JP 2024553621 A JP2024553621 A JP 2024553621A JP 7844766 B2 JP7844766 B2 JP 7844766B2
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Japan
Prior art keywords
tuberculosis
treatment
nintedanib
drug
drugs
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JP2024553621A
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Japanese (ja)
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JP2025508098A (ja
JP2025508098A5 (https=
Inventor
宇 陸
効友 陳
雪▲テイ▼ 祁
▲ロ▼瑶 鄭
雷 付
▲イ▼▲エン▼ 張
寧 王
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Beijing Chest Hospital
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Beijing Chest Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024553621A 2022-04-29 2023-03-16 抗特発性肺線維症薬ニンテダニブの結核を治療するための使用 Active JP7844766B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202210463752.6 2022-04-29
CN202210463752.6A CN114732818B (zh) 2022-04-29 2022-04-29 一种抗特发性肺纤维化药物尼达尼布在结核病治疗中的应用
PCT/CN2023/081772 WO2023207398A1 (zh) 2022-04-29 2023-03-16 一种抗特发性肺纤维化药物尼达尼布在结核病治疗中的应用

Publications (3)

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JP2025508098A JP2025508098A (ja) 2025-03-21
JP2025508098A5 JP2025508098A5 (https=) 2025-06-16
JP7844766B2 true JP7844766B2 (ja) 2026-04-14

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ID=82285173

Family Applications (1)

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JP2024553621A Active JP7844766B2 (ja) 2022-04-29 2023-03-16 抗特発性肺線維症薬ニンテダニブの結核を治療するための使用

Country Status (5)

Country Link
US (1) US20250099458A1 (https=)
JP (1) JP7844766B2 (https=)
CN (1) CN114732818B (https=)
WO (1) WO2023207398A1 (https=)
ZA (1) ZA202405173B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114732818B (zh) * 2022-04-29 2023-02-10 首都医科大学附属北京胸科医院 一种抗特发性肺纤维化药物尼达尼布在结核病治疗中的应用
CN115645405B (zh) * 2022-11-10 2023-11-21 南方医科大学 顺苯磺酸阿曲库铵在制备抗结核抗生素增效剂中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902507A (zh) 2016-06-12 2016-08-31 佛山市腾瑞医药科技有限公司 一种乙磺酸尼达尼布制剂及其应用
CN107019697A (zh) 2016-02-02 2017-08-08 瑞阳(苏州)生物科技有限公司 预防或治疗纤维化疾病的药物组合物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857725A (zh) * 2006-04-11 2006-11-08 济南帅华医药科技有限公司 一种含增效剂的复方抗结核药物缓释制剂
EP2311457A1 (en) * 2009-10-19 2011-04-20 Forschungszentrum Borstel Pharmaceutical compositions for treating infections with drug resistant mycobacteria
WO2015107482A1 (en) * 2014-01-17 2015-07-23 Piramal Enterprises Limited Pharmaceutical combination for treatment of tuberculosis
DK3377064T3 (da) * 2016-01-08 2019-09-23 Nerre Therapeutics Ltd Orvepitant til behandling af kronisk hoste
GB201607865D0 (en) * 2016-05-05 2016-06-22 Ucl Business Plc Anti-tuberculous polymersomes
CN114732818B (zh) * 2022-04-29 2023-02-10 首都医科大学附属北京胸科医院 一种抗特发性肺纤维化药物尼达尼布在结核病治疗中的应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107019697A (zh) 2016-02-02 2017-08-08 瑞阳(苏州)生物科技有限公司 预防或治疗纤维化疾病的药物组合物及其应用
CN105902507A (zh) 2016-06-12 2016-08-31 佛山市腾瑞医药科技有限公司 一种乙磺酸尼达尼布制剂及其应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Molecules,2019年11月29日,Vol. 24, No. 23,p.4373,DOI:10.3390/molecules24234373
日本結核病学会治療委員会,「結核医療の基準」の改定-2018年 ,結核,2018年,Vol.93,No.1,p.61-68

Also Published As

Publication number Publication date
ZA202405173B (en) 2024-07-31
JP2025508098A (ja) 2025-03-21
US20250099458A1 (en) 2025-03-27
CN114732818A (zh) 2022-07-12
WO2023207398A1 (zh) 2023-11-02
CN114732818B (zh) 2023-02-10

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