JP7812612B2 - 抗ｃｄ３８抗体の皮下投与 - Google Patents

抗ｃｄ３８抗体の皮下投与

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Publication number
JP7812612B2
JP7812612B2 JP2020560111A JP2020560111A JP7812612B2 JP 7812612 B2 JP7812612 B2 JP 7812612B2 JP 2020560111 A JP2020560111 A JP 2020560111A JP 2020560111 A JP2020560111 A JP 2020560111A JP 7812612 B2 JP7812612 B2 JP 7812612B2
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JP
Japan
Prior art keywords
antibody
cells
seq
amino acid
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020560111A
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English (en)
Japanese (ja)
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JP2021510737A (ja
JP2021510737A5 (cg-RX-API-DMAC10.html
Inventor
ダール、マーティン
フェディク、エリック
エヴァンス、ロバート
ザオ、リン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of JP2021510737A publication Critical patent/JP2021510737A/ja
Publication of JP2021510737A5 publication Critical patent/JP2021510737A5/ja
Priority to JP2023190427A priority Critical patent/JP2024023247A/ja
Application granted granted Critical
Publication of JP7812612B2 publication Critical patent/JP7812612B2/ja
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020560111A 2018-01-12 2019-01-14 抗ｃｄ３８抗体の皮下投与 Active JP7812612B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023190427A JP2024023247A (ja) 2018-01-12 2023-11-07 抗ｃｄ３８抗体の皮下投与

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862617146P 2018-01-12 2018-01-12
US62/617,146 2018-01-12
PCT/US2019/013547 WO2019140410A1 (en) 2018-01-12 2019-01-14 Subcutaneous dosing of anti-cd38 antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023190427A Division JP2024023247A (ja) 2018-01-12 2023-11-07 抗ｃｄ３８抗体の皮下投与

Publications (3)

Publication Number Publication Date
JP2021510737A JP2021510737A (ja) 2021-04-30
JP2021510737A5 JP2021510737A5 (cg-RX-API-DMAC10.html) 2022-02-24
JP7812612B2 true JP7812612B2 (ja) 2026-02-10

Family

ID=65529766

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020560111A Active JP7812612B2 (ja) 2018-01-12 2019-01-14 抗ｃｄ３８抗体の皮下投与
JP2023190427A Pending JP2024023247A (ja) 2018-01-12 2023-11-07 抗ｃｄ３８抗体の皮下投与

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023190427A Pending JP2024023247A (ja) 2018-01-12 2023-11-07 抗ｃｄ３８抗体の皮下投与

Country Status (11)

Country Link
US (2) US12371506B2 (cg-RX-API-DMAC10.html)
EP (1) EP3737702B1 (cg-RX-API-DMAC10.html)
JP (2) JP7812612B2 (cg-RX-API-DMAC10.html)
KR (1) KR20210006321A (cg-RX-API-DMAC10.html)
CN (1) CN112739715A (cg-RX-API-DMAC10.html)
AU (1) AU2019208102B2 (cg-RX-API-DMAC10.html)
BR (1) BR112020014052A2 (cg-RX-API-DMAC10.html)
CA (1) CA3088199A1 (cg-RX-API-DMAC10.html)
CO (1) CO2020008561A2 (cg-RX-API-DMAC10.html)
MX (2) MX2020007429A (cg-RX-API-DMAC10.html)
WO (1) WO2019140410A1 (cg-RX-API-DMAC10.html)

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JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
MA45674A (fr) 2016-07-15 2019-05-22 Takeda Pharmaceuticals Co Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes
MX2020007429A (es) 2018-01-12 2020-10-15 Takeda Pharmaceuticals Co Dosificacion subcutanea de anticuerpos anti grupo de diferenciacion 38 (cd38).
WO2020146795A1 (en) 2019-01-11 2020-07-16 Omeros Corporation Methods and compositions for treating cancer
CN112876563B (zh) * 2019-11-29 2022-08-16 康诺亚生物医药科技（成都）有限公司 药物组合物及其制备方法和应用
CN116635420A (zh) * 2020-09-10 2023-08-22 英创远达制药公司 血液筛查方法
US12181485B2 (en) * 2020-09-10 2024-12-31 CASI Pharmaceuticals, Inc Methods of blood screening
IL302640A (en) * 2020-11-03 2023-07-01 Sanofi Aventis Us Llc Use of isatuximab for the treatment of multiple myeloma
KR20250135226A (ko) 2023-01-06 2025-09-12 다케다 야쿠힌 고교 가부시키가이샤 자가면역 질환의 치료를 위한 항-cd38 항체
KR20250052963A (ko) 2023-10-12 2025-04-21 주식회사 쿠노소프트 글로벌 지능형 b2b 기업매칭 시스템
WO2025160986A1 (en) * 2024-02-02 2025-08-07 Keymed Biosciences (Chengdu) Co., Ltd. An anti-cd38 monoclonal antibody and application thereof
WO2025193746A1 (en) 2024-03-12 2025-09-18 Takeda Pharmaceutical Company Limited Dosing regimens of anti-cd38 antibodies for treatment of subjects with immune thrombocytopenia
WO2025213286A1 (zh) * 2024-04-07 2025-10-16 中国医学科学院血液病医院(中国医学科学院血液学研究所) 一种阻断单核巨噬细胞功能的cd38抑制剂在治疗itp中的应用
WO2025235919A1 (en) 2024-05-09 2025-11-13 Takeda Pharmaceutical Company Limited Dosing regimens of anti-cd38 antibodies for treatment of subjects with immunoglobulin a nephropathy

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Also Published As

Publication number Publication date
MX2020007429A (es) 2020-10-15
BR112020014052A2 (pt) 2020-12-08
US20210388103A1 (en) 2021-12-16
JP2024023247A (ja) 2024-02-21
EP3737702A1 (en) 2020-11-18
EP3737702B1 (en) 2026-07-29
RU2020126723A3 (cg-RX-API-DMAC10.html) 2022-02-14
US20260103534A1 (en) 2026-04-16
CN112739715A (zh) 2021-04-30
KR20210006321A (ko) 2021-01-18
JP2021510737A (ja) 2021-04-30
WO2019140410A1 (en) 2019-07-18
US12371506B2 (en) 2025-07-29
AU2019208102A1 (en) 2020-07-02
CO2020008561A2 (es) 2020-10-30
MX2026000035A (es) 2026-06-01
RU2020126723A (ru) 2022-02-14
CA3088199A1 (en) 2019-07-18
AU2019208102B2 (en) 2025-10-09

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