JP7806051B2 - 核酸オリゴマーを含む組成物 - Google Patents

核酸オリゴマーを含む組成物

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Publication number
JP7806051B2
JP7806051B2 JP2023533547A JP2023533547A JP7806051B2 JP 7806051 B2 JP7806051 B2 JP 7806051B2 JP 2023533547 A JP2023533547 A JP 2023533547A JP 2023533547 A JP2023533547 A JP 2023533547A JP 7806051 B2 JP7806051 B2 JP 7806051B2
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Japan
Prior art keywords
group
formula
nucleic acid
solution
independently
Prior art date
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JP2023533547A
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English (en)
Japanese (ja)
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JPWO2023282120A5 (https=
JPWO2023282120A1 (https=
Inventor
悠也 森山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
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Publication of JPWO2023282120A1 publication Critical patent/JPWO2023282120A1/ja
Publication of JPWO2023282120A5 publication Critical patent/JPWO2023282120A5/ja
Application granted granted Critical
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
JP2023533547A 2021-07-06 2022-06-28 核酸オリゴマーを含む組成物 Active JP7806051B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021112316 2021-07-06
JP2021112316 2021-07-06
PCT/JP2022/025692 WO2023282120A1 (ja) 2021-07-06 2022-06-28 核酸オリゴマーを含む組成物

Publications (3)

Publication Number Publication Date
JPWO2023282120A1 JPWO2023282120A1 (https=) 2023-01-12
JPWO2023282120A5 JPWO2023282120A5 (https=) 2025-05-08
JP7806051B2 true JP7806051B2 (ja) 2026-01-26

Family

ID=84801563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023533547A Active JP7806051B2 (ja) 2021-07-06 2022-06-28 核酸オリゴマーを含む組成物

Country Status (6)

Country Link
US (1) US20240300993A1 (https=)
EP (1) EP4368627A4 (https=)
JP (1) JP7806051B2 (https=)
KR (1) KR20240028416A (https=)
CN (1) CN117425663B (https=)
WO (1) WO2023282120A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4675778A1 (en) 2023-02-28 2026-01-07 SBTL Advanced Materials Co. Ltd. Stainless steel pouch film for secondary battery

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017115655A1 (ja) 2015-12-28 2017-07-06 昭和電工株式会社 分離分析方法
WO2018212236A1 (ja) 2017-05-16 2018-11-22 日産化学株式会社 オリゴヌクレオチドの製造方法
JP2020515525A (ja) 2017-02-03 2020-05-28 ジーン シグナル インターナショナル ソシエテ アノニム 安定なホスホロチオエートオリゴヌクレオチドを含む無菌製剤
WO2020196890A1 (ja) 2019-03-28 2020-10-01 味の素株式会社 ホスホロチオエート化部位を有するオリゴヌクレオチドの製造方法
WO2021024467A1 (ja) 2019-08-08 2021-02-11 住友化学株式会社 一本鎖rnaの製造方法
WO2021024465A1 (ja) 2019-08-08 2021-02-11 住友化学株式会社 核酸分子の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687808A (en) 1969-08-14 1972-08-29 Univ Leland Stanford Junior Synthetic polynucleotides
JPH07170981A (ja) * 1993-12-17 1995-07-11 Res Dev Corp Of Japan オリゴヌクレオチドの製造法
AU2005275801B2 (en) 2004-08-26 2012-05-10 Nippon Shinyaku Co., Ltd. Phosphoramidite compound and method for producing oligo-RNA
US8138330B2 (en) * 2006-09-11 2012-03-20 Sigma-Aldrich Co. Llc Process for the synthesis of oligonucleotides
MX370398B (es) 2011-08-25 2019-12-11 Bonac Corp Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico.
EP3159407A1 (en) 2015-10-23 2017-04-26 Silence Therapeutics (London) Ltd Guide rnas, methods and uses
TWI729028B (zh) * 2015-11-17 2021-06-01 日商日產化學工業股份有限公司 寡核苷酸的製造方法
CN116063365A (zh) * 2015-12-16 2023-05-05 味之素株式会社 寡核苷酸的制备方法以及核苷、核苷酸或寡核苷酸
KR102670605B1 (ko) 2018-04-24 2024-05-29 스미또모 가가꾸 가부시끼가이샤 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법
CN115397831B (zh) * 2020-04-14 2026-02-24 住友化学株式会社 包含核酸寡聚物的组合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017115655A1 (ja) 2015-12-28 2017-07-06 昭和電工株式会社 分離分析方法
JP2020515525A (ja) 2017-02-03 2020-05-28 ジーン シグナル インターナショナル ソシエテ アノニム 安定なホスホロチオエートオリゴヌクレオチドを含む無菌製剤
WO2018212236A1 (ja) 2017-05-16 2018-11-22 日産化学株式会社 オリゴヌクレオチドの製造方法
WO2020196890A1 (ja) 2019-03-28 2020-10-01 味の素株式会社 ホスホロチオエート化部位を有するオリゴヌクレオチドの製造方法
WO2021024467A1 (ja) 2019-08-08 2021-02-11 住友化学株式会社 一本鎖rnaの製造方法
WO2021024465A1 (ja) 2019-08-08 2021-02-11 住友化学株式会社 核酸分子の製造方法

Also Published As

Publication number Publication date
CN117425663A (zh) 2024-01-19
EP4368627A4 (en) 2025-10-08
US20240300993A1 (en) 2024-09-12
WO2023282120A1 (ja) 2023-01-12
CN117425663B (zh) 2026-04-17
EP4368627A1 (en) 2024-05-15
KR20240028416A (ko) 2024-03-05
JPWO2023282120A1 (https=) 2023-01-12

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