JP7800447B2 - 粒子分析装置、粒子分析方法及び光学測定装置 - Google Patents

粒子分析装置、粒子分析方法及び光学測定装置

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Publication number
JP7800447B2
JP7800447B2 JP2022575139A JP2022575139A JP7800447B2 JP 7800447 B2 JP7800447 B2 JP 7800447B2 JP 2022575139 A JP2022575139 A JP 2022575139A JP 2022575139 A JP2022575139 A JP 2022575139A JP 7800447 B2 JP7800447 B2 JP 7800447B2
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JP
Japan
Prior art keywords
lens
lenses
light
excitation light
frame
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022575139A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022153736A1 (https=
Inventor
丈司 畠山
聡史 長江
幹修 野中
謙次 石田
直道 菊地
隆史 加藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Sony Group Corp
Original Assignee
Sony Corp
Sony Group Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp, Sony Group Corp filed Critical Sony Corp
Publication of JPWO2022153736A1 publication Critical patent/JPWO2022153736A1/ja
Application granted granted Critical
Publication of JP7800447B2 publication Critical patent/JP7800447B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2022575139A 2021-01-14 2021-12-09 粒子分析装置、粒子分析方法及び光学測定装置 Active JP7800447B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021004282 2021-01-14
JP2021004282 2021-01-14
PCT/JP2021/045300 WO2022153736A1 (ja) 2021-01-14 2021-12-09 粒子分析装置、粒子分析方法及び光学測定装置

Publications (2)

Publication Number Publication Date
JPWO2022153736A1 JPWO2022153736A1 (https=) 2022-07-21
JP7800447B2 true JP7800447B2 (ja) 2026-01-16

Family

ID=82448339

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022575139A Active JP7800447B2 (ja) 2021-01-14 2021-12-09 粒子分析装置、粒子分析方法及び光学測定装置

Country Status (4)

Country Link
US (1) US12379304B2 (https=)
JP (1) JP7800447B2 (https=)
CN (1) CN116670493A (https=)
WO (1) WO2022153736A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003090945A (ja) 2001-07-10 2003-03-28 Olympus Optical Co Ltd レンズ保持装置および顕微鏡用対物レンズ
JP2004219608A (ja) 2003-01-14 2004-08-05 Kurobane Nikon:Kk 対物レンズ及びこの対物レンズを備える顕微鏡
JP4252447B2 (ja) 2001-06-22 2009-04-08 カール ツァイス イェナ ゲーエムベーハー 対物レンズ
JP2015038539A (ja) 2012-10-26 2015-02-26 シャープ株式会社 レンズ素子
WO2016185623A1 (ja) 2015-05-18 2016-11-24 シャープ株式会社 微小粒子検出装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040070846A1 (en) 2001-06-22 2004-04-15 Hans-Juergen Dobschal Objective
US6704151B2 (en) * 2001-07-10 2004-03-09 Olympus Optical Co., Ltd. Optical unit and method for assembling the same
JP4817442B2 (ja) * 2006-07-31 2011-11-16 シスメックス株式会社 粒子分析装置用光学系、及びそれを用いた粒子分析装置
JP4990746B2 (ja) 2007-12-14 2012-08-01 ベイバイオサイエンス株式会社 液体フローに含まれる生物学的粒子を分別する装置ならびにその方法
JP5720233B2 (ja) 2010-12-17 2015-05-20 ソニー株式会社 マイクロチップ及び微小粒子分取装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4252447B2 (ja) 2001-06-22 2009-04-08 カール ツァイス イェナ ゲーエムベーハー 対物レンズ
JP2003090945A (ja) 2001-07-10 2003-03-28 Olympus Optical Co Ltd レンズ保持装置および顕微鏡用対物レンズ
JP2004219608A (ja) 2003-01-14 2004-08-05 Kurobane Nikon:Kk 対物レンズ及びこの対物レンズを備える顕微鏡
JP2015038539A (ja) 2012-10-26 2015-02-26 シャープ株式会社 レンズ素子
WO2016185623A1 (ja) 2015-05-18 2016-11-24 シャープ株式会社 微小粒子検出装置

Also Published As

Publication number Publication date
CN116670493A (zh) 2023-08-29
US12379304B2 (en) 2025-08-05
US20240068925A1 (en) 2024-02-29
JPWO2022153736A1 (https=) 2022-07-21
WO2022153736A1 (ja) 2022-07-21

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