CN116670493A - 粒子分析器、粒子分析方法和光学测量装置 - Google Patents

粒子分析器、粒子分析方法和光学测量装置 Download PDF

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Publication number
CN116670493A
CN116670493A CN202180089609.9A CN202180089609A CN116670493A CN 116670493 A CN116670493 A CN 116670493A CN 202180089609 A CN202180089609 A CN 202180089609A CN 116670493 A CN116670493 A CN 116670493A
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CN
China
Prior art keywords
lens
lenses
light
excitation light
particle analyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180089609.9A
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English (en)
Chinese (zh)
Inventor
畠山丈司
长江聪史
野中干修
石田谦次
菊地直道
加藤隆史
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Group Corp
Original Assignee
Sony Group Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Group Corp filed Critical Sony Group Corp
Publication of CN116670493A publication Critical patent/CN116670493A/zh
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN202180089609.9A 2021-01-14 2021-12-09 粒子分析器、粒子分析方法和光学测量装置 Pending CN116670493A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021004282 2021-01-14
JP2021-004282 2021-01-14
PCT/JP2021/045300 WO2022153736A1 (ja) 2021-01-14 2021-12-09 粒子分析装置、粒子分析方法及び光学測定装置

Publications (1)

Publication Number Publication Date
CN116670493A true CN116670493A (zh) 2023-08-29

Family

ID=82448339

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180089609.9A Pending CN116670493A (zh) 2021-01-14 2021-12-09 粒子分析器、粒子分析方法和光学测量装置

Country Status (4)

Country Link
US (1) US12379304B2 (https=)
JP (1) JP7800447B2 (https=)
CN (1) CN116670493A (https=)
WO (1) WO2022153736A1 (https=)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10130212A1 (de) 2001-06-22 2003-01-02 Zeiss Carl Jena Gmbh Objektiv
US20040070846A1 (en) 2001-06-22 2004-04-15 Hans-Juergen Dobschal Objective
JP2003090945A (ja) 2001-07-10 2003-03-28 Olympus Optical Co Ltd レンズ保持装置および顕微鏡用対物レンズ
US6704151B2 (en) * 2001-07-10 2004-03-09 Olympus Optical Co., Ltd. Optical unit and method for assembling the same
JP2004219608A (ja) 2003-01-14 2004-08-05 Kurobane Nikon:Kk 対物レンズ及びこの対物レンズを備える顕微鏡
JP4817442B2 (ja) * 2006-07-31 2011-11-16 シスメックス株式会社 粒子分析装置用光学系、及びそれを用いた粒子分析装置
JP4990746B2 (ja) 2007-12-14 2012-08-01 ベイバイオサイエンス株式会社 液体フローに含まれる生物学的粒子を分別する装置ならびにその方法
JP5720233B2 (ja) 2010-12-17 2015-05-20 ソニー株式会社 マイクロチップ及び微小粒子分取装置
JP2015038539A (ja) 2012-10-26 2015-02-26 シャープ株式会社 レンズ素子
JP5864009B1 (ja) 2015-05-18 2016-02-17 シャープ株式会社 微小粒子検出装置

Also Published As

Publication number Publication date
US12379304B2 (en) 2025-08-05
US20240068925A1 (en) 2024-02-29
JPWO2022153736A1 (https=) 2022-07-21
JP7800447B2 (ja) 2026-01-16
WO2022153736A1 (ja) 2022-07-21

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