JP7783834B2 - Ｔｉｅ－２の活性化物質による急性呼吸窮迫症候群の処置方法 - Google Patents

Ｔｉｅ－２の活性化物質による急性呼吸窮迫症候群の処置方法

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Publication number
JP7783834B2
JP7783834B2 JP2022569498A JP2022569498A JP7783834B2 JP 7783834 B2 JP7783834 B2 JP 7783834B2 JP 2022569498 A JP2022569498 A JP 2022569498A JP 2022569498 A JP2022569498 A JP 2022569498A JP 7783834 B2 JP7783834 B2 JP 7783834B2
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tie
compound
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Japanese (ja)
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JP2023526790A5 (enExample
JP2023526790A (ja
Inventor
ケビン ピータース，
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Eyepoint Pharmaceuticals Inc
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Eyepoint Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022569498A 2020-05-21 2021-05-20 Ｔｉｅ－２の活性化物質による急性呼吸窮迫症候群の処置方法 Active JP7783834B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063028317P 2020-05-21 2020-05-21
US63/028,317 2020-05-21
PCT/US2021/033495 WO2021236985A1 (en) 2020-05-21 2021-05-20 Methods of treating acute respiratory distress syndrome with activators of tie-2

Publications (3)

Publication Number Publication Date
JP2023526790A JP2023526790A (ja) 2023-06-23
JP2023526790A5 JP2023526790A5 (enExample) 2024-05-27
JP7783834B2 true JP7783834B2 (ja) 2025-12-10

Family

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Family Applications (1)

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JP2022569498A Active JP7783834B2 (ja) 2020-05-21 2021-05-20 Ｔｉｅ－２の活性化物質による急性呼吸窮迫症候群の処置方法

Country Status (7)

Country Link
US (1) US12544362B2 (enExample)
EP (1) EP4153237A4 (enExample)
JP (1) JP7783834B2 (enExample)
CN (1) CN115666651A (enExample)
AU (1) AU2021275224A1 (enExample)
CA (1) CA3177415A1 (enExample)
WO (1) WO2021236985A1 (enExample)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012515169A (ja) 2009-01-12 2012-07-05 アケビア セラピューティクス インコーポレイテッド 血管漏出症候群を治療する方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2195958C1 (ru) * 2002-02-19 2003-01-10 Центральный научно-исследовательский институт туберкулеза РАМН Способ лечения синдрома острого повреждения легких после расширенных оперативных вмешательств
WO2004075838A2 (en) * 2003-02-21 2004-09-10 Rikshospitalet-Radiumhospitalet Hf Method and compositions for the treatment of meconium aspiration syndrome
WO2005034929A2 (en) * 2003-10-10 2005-04-21 Fibrogen, Inc. Tissue remodeling and vascularization
WO2007084136A2 (en) * 2006-01-23 2007-07-26 Ony, Inc. Treatment of acute respiratory distress syndrome
US9096555B2 (en) * 2009-01-12 2015-08-04 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome
ES2743509T3 (es) * 2013-04-11 2020-02-19 Sunnybrook Res Inst Métodos, usos y composiciones de agonistas de Tie2
CN106456666A (zh) * 2014-01-10 2017-02-22 Ino治疗有限责任公司 使用吸入性一氧化氮气体来治疗儿童的急性呼吸窘迫综合征的方法
WO2017100796A1 (en) * 2015-12-11 2017-06-15 SINACA, Academia Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
WO2020214851A1 (en) * 2019-04-18 2020-10-22 Aerpio Pharmaceuticals, Inc. Methods of treating hypertension with activators of tie-2

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012515169A (ja) 2009-01-12 2012-07-05 アケビア セラピューティクス インコーポレイテッド 血管漏出症候群を治療する方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Am J Trop Med Hyg，2015年，Vol. 93, No. 4, Suppl.，p. 76

Also Published As

Publication number Publication date
US12544362B2 (en) 2026-02-10
CA3177415A1 (en) 2021-11-25
AU2021275224A1 (en) 2022-10-13
EP4153237A1 (en) 2023-03-29
WO2021236985A1 (en) 2021-11-25
EP4153237A4 (en) 2024-07-03
CN115666651A (zh) 2023-01-31
US20240299367A1 (en) 2024-09-12
JP2023526790A (ja) 2023-06-23

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