JP7778069B2 - 高親油性生理活性物質の放出制御製剤 - Google Patents

高親油性生理活性物質の放出制御製剤

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Publication number
JP7778069B2
JP7778069B2 JP2022521684A JP2022521684A JP7778069B2 JP 7778069 B2 JP7778069 B2 JP 7778069B2 JP 2022521684 A JP2022521684 A JP 2022521684A JP 2022521684 A JP2022521684 A JP 2022521684A JP 7778069 B2 JP7778069 B2 JP 7778069B2
Authority
JP
Japan
Prior art keywords
formulation
highly lipophilic
matrix
cannabinoids
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022521684A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022553653A5 (https=
JP2022553653A (ja
JPWO2021074403A5 (https=
Inventor
ノヴァク，ミルコ
ジェスコ ノヴァク，ジェイ
グラーヴェ，アネット
ヴェンツラフ，モニカ
バルトルト，サラ
ゴイゲリン，クリスティアン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADD Advanced Drug Delivery Technologies AG
Original Assignee
ADD Advanced Drug Delivery Technologies AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADD Advanced Drug Delivery Technologies AG filed Critical ADD Advanced Drug Delivery Technologies AG
Publication of JP2022553653A publication Critical patent/JP2022553653A/ja
Publication of JP2022553653A5 publication Critical patent/JP2022553653A5/ja
Publication of JPWO2021074403A5 publication Critical patent/JPWO2021074403A5/ja
Priority to JP2025169943A priority Critical patent/JP2025182116A/ja
Application granted granted Critical
Publication of JP7778069B2 publication Critical patent/JP7778069B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022521684A 2019-10-16 2020-10-16 高親油性生理活性物質の放出制御製剤 Active JP7778069B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025169943A JP2025182116A (ja) 2019-10-16 2025-10-08 高親油性生理活性物質の放出制御製剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19203580.6A EP3808341A1 (de) 2019-10-16 2019-10-16 Kontrolliert freisetzende formulierungen stark lipophiler physiologisch aktiver substanzen
EP19203580.6 2019-10-16
PCT/EP2020/079248 WO2021074403A1 (de) 2019-10-16 2020-10-16 Kontrolliert freisetzende formulierungen stark lipophiler physiologisch aktiver substanzen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025169943A Division JP2025182116A (ja) 2019-10-16 2025-10-08 高親油性生理活性物質の放出制御製剤

Publications (4)

Publication Number Publication Date
JP2022553653A JP2022553653A (ja) 2022-12-26
JP2022553653A5 JP2022553653A5 (https=) 2023-10-19
JPWO2021074403A5 JPWO2021074403A5 (https=) 2023-10-19
JP7778069B2 true JP7778069B2 (ja) 2025-12-01

Family

ID=68281185

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022521684A Active JP7778069B2 (ja) 2019-10-16 2020-10-16 高親油性生理活性物質の放出制御製剤
JP2025169943A Pending JP2025182116A (ja) 2019-10-16 2025-10-08 高親油性生理活性物質の放出制御製剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025169943A Pending JP2025182116A (ja) 2019-10-16 2025-10-08 高親油性生理活性物質の放出制御製剤

Country Status (10)

Country Link
US (1) US20240139215A1 (https=)
EP (2) EP3808341A1 (https=)
JP (2) JP7778069B2 (https=)
CN (1) CN114945353A (https=)
AU (1) AU2020365443A1 (https=)
BR (1) BR112022006643A2 (https=)
CA (1) CA3157654A1 (https=)
IL (1) IL292018A (https=)
MX (1) MX2022004523A (https=)
WO (1) WO2021074403A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3808336A1 (de) * 2019-10-16 2021-04-21 ADD Advanced Drug Delivery Technologies, Ltd. Kontrolliert freisetzende formulierungen stark lipophiler physiologisch aktiver substanzen
US20240317701A1 (en) 2020-12-17 2024-09-26 Nalu Bio, Inc. Synthesis of cannabidiol and analogs thereof, and related compounds, formulations, and methods of use
GB2618322A (en) * 2022-04-29 2023-11-08 113 Botanicals Ltd Compositions and methods

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008024490A2 (en) 2006-08-24 2008-02-28 Theraquest Biosciences, Inc. Oral pharmaceutical formulations of abuse deterrent cannabinoids and method of use
JP2009035564A (ja) 2001-03-01 2009-02-19 Aska Pharmaceutical Co Ltd フェノフィブラート含有組成物
JP2019523296A (ja) 2016-07-14 2019-08-22 アイシーディーファルマ・リミテッド カンナビノイドの自己乳化組成物
JP2019137614A (ja) 2018-02-06 2019-08-22 富士フイルム株式会社 経口用医薬組成物及びその製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1361864T3 (en) * 2001-02-14 2014-03-03 Gw Pharma Ltd FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids
DE10226494A1 (de) * 2002-06-14 2004-01-08 Lts Lohmann Therapie-Systeme Ag Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen
AU2014340709B2 (en) 2013-10-29 2019-07-04 Echo Pharmaceuticals B.V. Compressed tablet containing cannabidiol, method for its manufacture and use of such tablet in oral treatment of psychosis or anxiety disorders
DE102014213548A1 (de) * 2014-07-11 2016-01-14 Hans Brammer Cannabispräparat
HRP20200326T1 (hr) * 2014-08-11 2020-06-12 Perora Gmbh Formulacija koja sadrži čestice
WO2018035030A1 (en) 2016-08-15 2018-02-22 Corr-Jensen Inc. Time release fat-soluble actives
DE102019100483A1 (de) * 2019-01-10 2020-07-16 Lts Lohmann Therapie-Systeme Ag Oraler Dünnfilm

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009035564A (ja) 2001-03-01 2009-02-19 Aska Pharmaceutical Co Ltd フェノフィブラート含有組成物
WO2008024490A2 (en) 2006-08-24 2008-02-28 Theraquest Biosciences, Inc. Oral pharmaceutical formulations of abuse deterrent cannabinoids and method of use
JP2019523296A (ja) 2016-07-14 2019-08-22 アイシーディーファルマ・リミテッド カンナビノイドの自己乳化組成物
JP2019137614A (ja) 2018-02-06 2019-08-22 富士フイルム株式会社 経口用医薬組成物及びその製造方法

Also Published As

Publication number Publication date
EP3808341A1 (de) 2021-04-21
CA3157654A1 (en) 2021-04-22
JP2022553653A (ja) 2022-12-26
JP2025182116A (ja) 2025-12-11
US20240139215A1 (en) 2024-05-02
IL292018A (en) 2022-06-01
EP4045014A1 (de) 2022-08-24
BR112022006643A2 (pt) 2022-07-12
MX2022004523A (es) 2022-09-19
WO2021074403A1 (de) 2021-04-22
CN114945353A (zh) 2022-08-26
AU2020365443A1 (en) 2022-06-02

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