JP7769868B2 - 遺伝子改変微生物および有機酸の製造方法 - Google Patents

遺伝子改変微生物および有機酸の製造方法

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Publication number
JP7769868B2
JP7769868B2 JP2021529758A JP2021529758A JP7769868B2 JP 7769868 B2 JP7769868 B2 JP 7769868B2 JP 2021529758 A JP2021529758 A JP 2021529758A JP 2021529758 A JP2021529758 A JP 2021529758A JP 7769868 B2 JP7769868 B2 JP 7769868B2
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Japan
Prior art keywords
acid
yeex
protein
microorganism
amino acid
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JP2021529758A
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English (en)
Japanese (ja)
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JPWO2021230222A1 (https=
JPWO2021230222A5 (https=
Inventor
仁美 中村
匡平 磯部
健司 河村
勝成 山田
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Toray Industries Inc
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Toray Industries Inc
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Publication of JPWO2021230222A5 publication Critical patent/JPWO2021230222A5/ja
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54Acetic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2021529758A 2020-05-12 2021-05-11 遺伝子改変微生物および有機酸の製造方法 Active JP7769868B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020083660 2020-05-12
JP2020083660 2020-05-12
PCT/JP2021/017802 WO2021230222A1 (ja) 2020-05-12 2021-05-11 遺伝子改変微生物および有機酸の製造方法

Publications (3)

Publication Number Publication Date
JPWO2021230222A1 JPWO2021230222A1 (https=) 2021-11-18
JPWO2021230222A5 JPWO2021230222A5 (https=) 2024-05-07
JP7769868B2 true JP7769868B2 (ja) 2025-11-14

Family

ID=78525882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021529758A Active JP7769868B2 (ja) 2020-05-12 2021-05-11 遺伝子改変微生物および有機酸の製造方法

Country Status (6)

Country Link
US (1) US20240294583A1 (https=)
EP (1) EP4151718A4 (https=)
JP (1) JP7769868B2 (https=)
CN (1) CN115551993B (https=)
BR (1) BR112022022819A2 (https=)
WO (1) WO2021230222A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020010328A2 (pt) * 2017-11-30 2020-11-17 Toray Industries, Inc. micro-organismo geneticamente modificado e métodos de produção de ácido 3-hidroxiadípico, ácido a-hidromucônico e ácido adípico

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019107516A1 (ja) 2017-11-30 2019-06-06 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0506369B1 (pt) * 2004-01-30 2020-11-03 Ajinomoto Co., Inc microorganismo transgênico, e, método para produzir um l-aminoácido
GB0410983D0 (en) 2004-05-17 2004-06-16 El Gewely Mohamed R Molecules
CN101115832A (zh) * 2004-11-26 2008-01-30 协和发酵工业株式会社 工业上有用的微生物
ES2656790T3 (es) * 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
JP2017192325A (ja) 2016-04-19 2017-10-26 三菱ケミカル株式会社 有機酸の製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019107516A1 (ja) 2017-11-30 2019-06-06 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GenBank [online], ACCESSION: HAH7807653, URL: <https://www.ncbi.nlm.nih.gov/protein/HAH7807653.1?rep
GenBank [online], ACCESSION: WP_129485903, URL: <https://www.ncbi.nlm.nih.gov/protein/WP_129485903.1
GenBank [online], ACCESSION: WP_147690482, URL: <https://www.ncbi.nlm.nih.gov/protein/WP_147690482.1

Also Published As

Publication number Publication date
CN115551993B (zh) 2025-08-05
BR112022022819A2 (pt) 2022-12-13
WO2021230222A1 (ja) 2021-11-18
EP4151718A4 (en) 2024-06-26
CN115551993A (zh) 2022-12-30
EP4151718A1 (en) 2023-03-22
US20240294583A1 (en) 2024-09-05
JPWO2021230222A1 (https=) 2021-11-18

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