JP7702871B2 - 腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ - Google Patents

腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ Download PDF

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JP7702871B2
JP7702871B2 JP2021541620A JP2021541620A JP7702871B2 JP 7702871 B2 JP7702871 B2 JP 7702871B2 JP 2021541620 A JP2021541620 A JP 2021541620A JP 2021541620 A JP2021541620 A JP 2021541620A JP 7702871 B2 JP7702871 B2 JP 7702871B2
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cancer
pet
peptide
acid
seq
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ル，ツェン‐ロン
ガオ，ソンギ
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ケース ウエスタン リザーブ ユニバーシティ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
  • Medicinal Preparation (AREA)
JP2021541620A 2019-01-17 2020-01-17 腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ Active JP7702871B2 (ja)

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JP2025003824A JP2025063147A (ja) 2019-01-17 2025-01-10 腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ

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US201962793789P 2019-01-17 2019-01-17
US62/793,789 2019-01-17
PCT/US2020/014110 WO2020150617A2 (en) 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellula matrix

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JP2025003824A Division JP2025063147A (ja) 2019-01-17 2025-01-10 腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ

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JP2022517662A JP2022517662A (ja) 2022-03-09
JP2022517662A5 JP2022517662A5 (https=) 2023-01-26
JP7702871B2 true JP7702871B2 (ja) 2025-07-04

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JP2025003824A Pending JP2025063147A (ja) 2019-01-17 2025-01-10 腫瘍細胞外マトリックスにおける腫瘍性タンパク質に特異的なペプチドｐｅｔ／ｓｐｅｃｔプローブ

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US (1) US12576168B2 (https=)
EP (1) EP3911373A4 (https=)
JP (2) JP7702871B2 (https=)
KR (1) KR20210115003A (https=)
CN (1) CN113727737A (https=)
AU (1) AU2020208492B2 (https=)
CA (1) CA3127188A1 (https=)
WO (1) WO2020150617A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112574280B (zh) * 2020-12-21 2022-05-17 北京大学第一医院 一种双酶体系探针及其应用
US20240252662A1 (en) * 2021-05-20 2024-08-01 Case Western Reserve University Peptide drug conjugates specific to fibronectin isotypes for cancer therapy
CN116370658B (zh) * 2023-03-08 2025-04-18 中国科学院深圳先进技术研究院 一种靶向肿瘤的超声造影剂及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180110886A1 (en) 2014-08-04 2018-04-26 Case Western Reserve University Molecular probes and methods of use
WO2018215627A1 (en) 2017-05-24 2018-11-29 ITM Isotopen Technologien München AG Novel psma-binding agents and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9011816B2 (en) * 2011-03-25 2015-04-21 Case Western Reserve University Fibronectin targeting contrast agent
WO2013106824A1 (en) * 2012-01-13 2013-07-18 Board Of Regents, The University Of Texas System Epherin receptor targeting agents
WO2016022597A1 (en) * 2014-08-04 2016-02-11 Case Western Reserve University Targeting peptides and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180110886A1 (en) 2014-08-04 2018-04-26 Case Western Reserve University Molecular probes and methods of use
WO2018215627A1 (en) 2017-05-24 2018-11-29 ITM Isotopen Technologien München AG Novel psma-binding agents and uses thereof

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EP3911373A2 (en) 2021-11-24
JP2025063147A (ja) 2025-04-15
CA3127188A1 (en) 2020-07-23
CN113727737A (zh) 2021-11-30
AU2020208492A1 (en) 2021-08-12
US12576168B2 (en) 2026-03-17
JP2022517662A (ja) 2022-03-09
WO2020150617A8 (en) 2021-02-18
WO2020150617A2 (en) 2020-07-23
KR20210115003A (ko) 2021-09-24
US20220160903A1 (en) 2022-05-26
EP3911373A4 (en) 2023-01-25
AU2020208492B2 (en) 2026-04-02

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