AU2020208492B2 - Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix - Google Patents

Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix

Info

Publication number
AU2020208492B2
AU2020208492B2 AU2020208492A AU2020208492A AU2020208492B2 AU 2020208492 B2 AU2020208492 B2 AU 2020208492B2 AU 2020208492 A AU2020208492 A AU 2020208492A AU 2020208492 A AU2020208492 A AU 2020208492A AU 2020208492 B2 AU2020208492 B2 AU 2020208492B2
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AU
Australia
Prior art keywords
seq
pet
peptide
cancer
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2020208492A
Other languages
English (en)
Other versions
AU2020208492A1 (en
Inventor
Songqi GAO
Zheng-Rong Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Case Western Reserve University
Original Assignee
Case Western Reserve University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Case Western Reserve University filed Critical Case Western Reserve University
Publication of AU2020208492A1 publication Critical patent/AU2020208492A1/en
Application granted granted Critical
Publication of AU2020208492B2 publication Critical patent/AU2020208492B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
  • Medicinal Preparation (AREA)
AU2020208492A 2019-01-17 2020-01-17 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix Active AU2020208492B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962793789P 2019-01-17 2019-01-17
US62/793,789 2019-01-17
PCT/US2020/014110 WO2020150617A2 (en) 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellula matrix

Publications (2)

Publication Number Publication Date
AU2020208492A1 AU2020208492A1 (en) 2021-08-12
AU2020208492B2 true AU2020208492B2 (en) 2026-04-02

Family

ID=71614081

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020208492A Active AU2020208492B2 (en) 2019-01-17 2020-01-17 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix

Country Status (8)

Country Link
US (1) US12576168B2 (https=)
EP (1) EP3911373A4 (https=)
JP (2) JP7702871B2 (https=)
KR (1) KR20210115003A (https=)
CN (1) CN113727737A (https=)
AU (1) AU2020208492B2 (https=)
CA (1) CA3127188A1 (https=)
WO (1) WO2020150617A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112574280B (zh) * 2020-12-21 2022-05-17 北京大学第一医院 一种双酶体系探针及其应用
US20240252662A1 (en) * 2021-05-20 2024-08-01 Case Western Reserve University Peptide drug conjugates specific to fibronectin isotypes for cancer therapy
CN116370658B (zh) * 2023-03-08 2025-04-18 中国科学院深圳先进技术研究院 一种靶向肿瘤的超声造影剂及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180110886A1 (en) * 2014-08-04 2018-04-26 Case Western Reserve University Molecular probes and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9011816B2 (en) * 2011-03-25 2015-04-21 Case Western Reserve University Fibronectin targeting contrast agent
WO2013106824A1 (en) * 2012-01-13 2013-07-18 Board Of Regents, The University Of Texas System Epherin receptor targeting agents
WO2016022597A1 (en) * 2014-08-04 2016-02-11 Case Western Reserve University Targeting peptides and methods of use
CA3060143A1 (en) 2017-05-24 2018-11-29 Itm Isotopen Technologien Munchen Ag Novel psma-binding agents and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180110886A1 (en) * 2014-08-04 2018-04-26 Case Western Reserve University Molecular probes and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HAN ZHENG, SERGEEVA OLGA, ROELLE SARAH, CHENG HAN, GAO SONGQI, LI YAJUAN, LEE ZHENGHONG, LU ZHENG-RONG: "Preparation and Evaluation of ZD2 Peptide 64 Cu-DOTA Conjugate as a Positron Emission Tomography Probe for Detection and Characterization of Prostate Cancer", ACS OMEGA, ACS PUBLICATIONS, US, vol. 4, no. 1, 31 January 2019 (2019-01-31), US, pages 1185 - 1190, XP093006674, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b02729 *

Also Published As

Publication number Publication date
EP3911373A2 (en) 2021-11-24
JP2025063147A (ja) 2025-04-15
CA3127188A1 (en) 2020-07-23
CN113727737A (zh) 2021-11-30
AU2020208492A1 (en) 2021-08-12
US12576168B2 (en) 2026-03-17
JP2022517662A (ja) 2022-03-09
WO2020150617A8 (en) 2021-02-18
WO2020150617A2 (en) 2020-07-23
JP7702871B2 (ja) 2025-07-04
KR20210115003A (ko) 2021-09-24
US20220160903A1 (en) 2022-05-26
EP3911373A4 (en) 2023-01-25

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