CA3127188A1 - Peptide pet/spect probes specific to oncoproteins in tumor extracellularmatrix - Google Patents

Peptide pet/spect probes specific to oncoproteins in tumor extracellularmatrix Download PDF

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Publication number
CA3127188A1
CA3127188A1 CA3127188A CA3127188A CA3127188A1 CA 3127188 A1 CA3127188 A1 CA 3127188A1 CA 3127188 A CA3127188 A CA 3127188A CA 3127188 A CA3127188 A CA 3127188A CA 3127188 A1 CA3127188 A1 CA 3127188A1
Authority
CA
Canada
Prior art keywords
seq
cancer
derivatives
pet
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3127188A
Other languages
English (en)
French (fr)
Inventor
Zheng-Rong Lu
Songqi GAO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Case Western Reserve University
Original Assignee
Case Western Reserve University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Case Western Reserve University filed Critical Case Western Reserve University
Publication of CA3127188A1 publication Critical patent/CA3127188A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
  • Medicinal Preparation (AREA)
CA3127188A 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellularmatrix Pending CA3127188A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962793789P 2019-01-17 2019-01-17
US62/793,789 2019-01-17
PCT/US2020/014110 WO2020150617A2 (en) 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellula matrix

Publications (1)

Publication Number Publication Date
CA3127188A1 true CA3127188A1 (en) 2020-07-23

Family

ID=71614081

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3127188A Pending CA3127188A1 (en) 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellularmatrix

Country Status (8)

Country Link
US (1) US12576168B2 (https=)
EP (1) EP3911373A4 (https=)
JP (2) JP7702871B2 (https=)
KR (1) KR20210115003A (https=)
CN (1) CN113727737A (https=)
AU (1) AU2020208492B2 (https=)
CA (1) CA3127188A1 (https=)
WO (1) WO2020150617A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112574280B (zh) * 2020-12-21 2022-05-17 北京大学第一医院 一种双酶体系探针及其应用
US20240252662A1 (en) * 2021-05-20 2024-08-01 Case Western Reserve University Peptide drug conjugates specific to fibronectin isotypes for cancer therapy
CN116370658B (zh) * 2023-03-08 2025-04-18 中国科学院深圳先进技术研究院 一种靶向肿瘤的超声造影剂及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9011816B2 (en) * 2011-03-25 2015-04-21 Case Western Reserve University Fibronectin targeting contrast agent
WO2013106824A1 (en) * 2012-01-13 2013-07-18 Board Of Regents, The University Of Texas System Epherin receptor targeting agents
WO2016022597A1 (en) * 2014-08-04 2016-02-11 Case Western Reserve University Targeting peptides and methods of use
US10925980B2 (en) * 2014-08-04 2021-02-23 Case Western Reserve University Molecular probes and methods of use
CA3060143A1 (en) 2017-05-24 2018-11-29 Itm Isotopen Technologien Munchen Ag Novel psma-binding agents and uses thereof

Also Published As

Publication number Publication date
EP3911373A2 (en) 2021-11-24
JP2025063147A (ja) 2025-04-15
CN113727737A (zh) 2021-11-30
AU2020208492A1 (en) 2021-08-12
US12576168B2 (en) 2026-03-17
JP2022517662A (ja) 2022-03-09
WO2020150617A8 (en) 2021-02-18
WO2020150617A2 (en) 2020-07-23
JP7702871B2 (ja) 2025-07-04
KR20210115003A (ko) 2021-09-24
US20220160903A1 (en) 2022-05-26
EP3911373A4 (en) 2023-01-25
AU2020208492B2 (en) 2026-04-02

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