KR20210115003A - 종양 세포외 기질의 종양단백질에 특이적인 펩티드 pet/spect 프로브 - Google Patents

종양 세포외 기질의 종양단백질에 특이적인 펩티드 pet/spect 프로브 Download PDF

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Publication number
KR20210115003A
KR20210115003A KR1020217025921A KR20217025921A KR20210115003A KR 20210115003 A KR20210115003 A KR 20210115003A KR 1020217025921 A KR1020217025921 A KR 1020217025921A KR 20217025921 A KR20217025921 A KR 20217025921A KR 20210115003 A KR20210115003 A KR 20210115003A
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South Korea
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seq
cancer
pet
derivatives
peptide
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KR1020217025921A
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English (en)
Korean (ko)
Inventor
쳉-롱 루
송치 가오
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케이스 웨스턴 리저브 유니버시티
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Publication of KR20210115003A publication Critical patent/KR20210115003A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
  • Medicinal Preparation (AREA)
KR1020217025921A 2019-01-17 2020-01-17 종양 세포외 기질의 종양단백질에 특이적인 펩티드 pet/spect 프로브 Pending KR20210115003A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962793789P 2019-01-17 2019-01-17
US62/793,789 2019-01-17
PCT/US2020/014110 WO2020150617A2 (en) 2019-01-17 2020-01-17 Peptide pet/spect probes specific to oncoproteins in tumor extracellula matrix

Publications (1)

Publication Number Publication Date
KR20210115003A true KR20210115003A (ko) 2021-09-24

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Application Number Title Priority Date Filing Date
KR1020217025921A Pending KR20210115003A (ko) 2019-01-17 2020-01-17 종양 세포외 기질의 종양단백질에 특이적인 펩티드 pet/spect 프로브

Country Status (8)

Country Link
US (1) US12576168B2 (https=)
EP (1) EP3911373A4 (https=)
JP (2) JP7702871B2 (https=)
KR (1) KR20210115003A (https=)
CN (1) CN113727737A (https=)
AU (1) AU2020208492B2 (https=)
CA (1) CA3127188A1 (https=)
WO (1) WO2020150617A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112574280B (zh) * 2020-12-21 2022-05-17 北京大学第一医院 一种双酶体系探针及其应用
US20240252662A1 (en) * 2021-05-20 2024-08-01 Case Western Reserve University Peptide drug conjugates specific to fibronectin isotypes for cancer therapy
CN116370658B (zh) * 2023-03-08 2025-04-18 中国科学院深圳先进技术研究院 一种靶向肿瘤的超声造影剂及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9011816B2 (en) * 2011-03-25 2015-04-21 Case Western Reserve University Fibronectin targeting contrast agent
WO2013106824A1 (en) * 2012-01-13 2013-07-18 Board Of Regents, The University Of Texas System Epherin receptor targeting agents
WO2016022597A1 (en) * 2014-08-04 2016-02-11 Case Western Reserve University Targeting peptides and methods of use
US10925980B2 (en) * 2014-08-04 2021-02-23 Case Western Reserve University Molecular probes and methods of use
CA3060143A1 (en) 2017-05-24 2018-11-29 Itm Isotopen Technologien Munchen Ag Novel psma-binding agents and uses thereof

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Publication number Publication date
EP3911373A2 (en) 2021-11-24
JP2025063147A (ja) 2025-04-15
CA3127188A1 (en) 2020-07-23
CN113727737A (zh) 2021-11-30
AU2020208492A1 (en) 2021-08-12
US12576168B2 (en) 2026-03-17
JP2022517662A (ja) 2022-03-09
WO2020150617A8 (en) 2021-02-18
WO2020150617A2 (en) 2020-07-23
JP7702871B2 (ja) 2025-07-04
US20220160903A1 (en) 2022-05-26
EP3911373A4 (en) 2023-01-25
AU2020208492B2 (en) 2026-04-02

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