JP7701734B2 - 抗aベータワクチン療法 - Google Patents

抗aベータワクチン療法 Download PDF

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Publication number
JP7701734B2
JP7701734B2 JP2021569155A JP2021569155A JP7701734B2 JP 7701734 B2 JP7701734 B2 JP 7701734B2 JP 2021569155 A JP2021569155 A JP 2021569155A JP 2021569155 A JP2021569155 A JP 2021569155A JP 7701734 B2 JP7701734 B2 JP 7701734B2
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Japan
Prior art keywords
vaccine composition
administered
disease
amyloid
alzheimer
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JP2021569155A
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English (en)
Japanese (ja)
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JP2022533422A5 (enExample
JP2022533422A (ja
Inventor
ファイファー,アンドレア
ムース,アンドレアス
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エイシー イミューン ソシエテ アノニム
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018Lipids, e.g. in lipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2021569155A 2019-05-21 2020-05-20 抗aベータワクチン療法 Active JP7701734B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP19175810.1 2019-05-21
EP19175810 2019-05-21
EP19185593.1 2019-07-10
EP19185593 2019-07-10
EP20171549 2020-04-27
EP20171549.7 2020-04-27
EP20172205 2020-04-29
EP20172205.5 2020-04-29
PCT/EP2020/064172 WO2020234405A1 (en) 2019-05-21 2020-05-20 Anti-abeta vaccine therapy

Publications (3)

Publication Number Publication Date
JP2022533422A JP2022533422A (ja) 2022-07-22
JP2022533422A5 JP2022533422A5 (enExample) 2023-05-29
JP7701734B2 true JP7701734B2 (ja) 2025-07-02

Family

ID=70740677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021569155A Active JP7701734B2 (ja) 2019-05-21 2020-05-20 抗aベータワクチン療法

Country Status (15)

Country Link
US (1) US20220226447A1 (enExample)
EP (1) EP3972633A1 (enExample)
JP (1) JP7701734B2 (enExample)
KR (1) KR20220010552A (enExample)
CN (1) CN113853214A (enExample)
AU (1) AU2020277682A1 (enExample)
BR (1) BR112021023209A2 (enExample)
CA (1) CA3138145A1 (enExample)
CL (1) CL2021003051A1 (enExample)
IL (1) IL288252A (enExample)
MX (1) MX2021014102A (enExample)
MY (1) MY210394A (enExample)
SG (1) SG11202112329RA (enExample)
TW (1) TW202110425A (enExample)
WO (1) WO2020234405A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021260193A1 (en) * 2020-06-25 2021-12-30 Medimmune Limited Prevention of axonal damage using antibody binding to amyloid beta 1-42
KR20250137159A (ko) * 2023-01-26 2025-09-17 에이씨 이뮨 에스에이 항-a베타 백신 요법
WO2025109524A1 (en) * 2023-11-22 2025-05-30 Ac Immune Sa Assays and methods for assessing vaccine preparations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014531455A (ja) 2011-09-23 2014-11-27 エーシー イミューン ソシエテ アノニム ワクチン療法
JP2021521149A (ja) 2018-04-10 2021-08-26 エイシー イミューン ソシエテ アノニム 抗−aベータ治療用ワクチン

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
KR101152557B1 (ko) * 2005-12-12 2012-09-07 에이씨 이뮨 에스.에이. 치료 백신
HUE055739T2 (hu) * 2009-03-18 2021-12-28 Ac Immune Sa Eljárás terápiás alkalmazásra
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
JP6027011B2 (ja) 2010-10-26 2016-11-16 エーシー イミューン ソシエテ アノニム 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014531455A (ja) 2011-09-23 2014-11-27 エーシー イミューン ソシエテ アノニム ワクチン療法
JP2021521149A (ja) 2018-04-10 2021-08-26 エイシー イミューン ソシエテ アノニム 抗−aベータ治療用ワクチン

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PLOS ONE,2016年,Vol. 11, No.3, e0152471

Also Published As

Publication number Publication date
WO2020234405A1 (en) 2020-11-26
CA3138145A1 (en) 2020-11-26
TW202110425A (zh) 2021-03-16
EP3972633A1 (en) 2022-03-30
JP2022533422A (ja) 2022-07-22
CL2021003051A1 (es) 2022-07-22
AU2020277682A1 (en) 2021-12-23
KR20220010552A (ko) 2022-01-25
SG11202112329RA (en) 2021-12-30
BR112021023209A2 (pt) 2022-01-18
MX2021014102A (es) 2022-02-11
CN113853214A (zh) 2021-12-28
US20220226447A1 (en) 2022-07-21
MY210394A (en) 2025-09-18
IL288252A (en) 2022-01-01

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