JP7696064B2 - トリアゾール誘導体のエナンチオマー（ｒ）体の製造方法 - Google Patents

トリアゾール誘導体のエナンチオマー（ｒ）体の製造方法 Download PDF

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Publication number
JP7696064B2
JP7696064B2 JP2024533623A JP2024533623A JP7696064B2 JP 7696064 B2 JP7696064 B2 JP 7696064B2 JP 2024533623 A JP2024533623 A JP 2024533623A JP 2024533623 A JP2024533623 A JP 2024533623A JP 7696064 B2 JP7696064 B2 JP 7696064B2
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group
enantiomer
triazole derivative
producing
chiral molecule
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Japanese (ja)
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JPWO2024014282A5 (https=
JPWO2024014282A1 (https=
Inventor
隆介 萩原
智大 梅野
悟 唐澤
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Kureha Corp
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Kureha Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024533623A 2022-07-14 2023-06-27 トリアゾール誘導体のエナンチオマー（ｒ）体の製造方法 Active JP7696064B2 (ja)

Applications Claiming Priority (3)

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JP2022113477 2022-07-14
JP2022113477 2022-07-14
PCT/JP2023/023822 WO2024014282A1 (ja) 2022-07-14 2023-06-27 トリアゾール誘導体のエナンチオマー（ｒ）体の製造方法

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JPWO2024014282A1 JPWO2024014282A1 (https=) 2024-01-18
JPWO2024014282A5 JPWO2024014282A5 (https=) 2024-11-20
JP7696064B2 true JP7696064B2 (ja) 2025-06-19

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JP2024533623A Active JP7696064B2 (ja) 2022-07-14 2023-06-27 トリアゾール誘導体のエナンチオマー（ｒ）体の製造方法

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US (1) US20260015329A1 (https=)
EP (1) EP4534531A4 (https=)
JP (1) JP7696064B2 (https=)
CN (1) CN119487009A (https=)
WO (1) WO2024014282A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019093522A1 (ja) 2017-11-13 2019-05-16 株式会社クレハ アゾール誘導体、中間体化合物、及びアゾール誘導体の製造方法、ならびに農園芸用薬剤及び工業用材料保護剤
WO2021230382A1 (ja) 2020-05-15 2021-11-18 株式会社クレハ トリアゾール誘導体の（－）－エナンチオマー、農園芸用薬剤および工業用材料保護剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0680605A (ja) * 1992-09-01 1994-03-22 Daicel Chem Ind Ltd 光学異性体の分離方法
JP3130396B2 (ja) * 1992-12-25 2001-01-31 ダイセル化学工業株式会社 光学異性体分離法
JPH0710822A (ja) * 1993-04-26 1995-01-13 Daicel Chem Ind Ltd アミノ酸エステルの光学異性体分離法
NL1004346C2 (nl) * 1996-10-23 1998-04-24 Dsm Nv Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019093522A1 (ja) 2017-11-13 2019-05-16 株式会社クレハ アゾール誘導体、中間体化合物、及びアゾール誘導体の製造方法、ならびに農園芸用薬剤及び工業用材料保護剤
WO2021230382A1 (ja) 2020-05-15 2021-11-18 株式会社クレハ トリアゾール誘導体の（－）－エナンチオマー、農園芸用薬剤および工業用材料保護剤

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BAGI, P. et al.，The resolution of acyclic P-stereogenic phosphine oxides via the formation of diastereomeric complexes: A case study on ethyl-(2- methylphenyl)-phenylphosphine oxide，Chirality，2018年，Vol. 30，No. 4，pp. 509-522，DOI: 10.1002/chir.22816
SEEBACH, D. et al.，On the Mechanisms of Enantioselective Reactions Using α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanol(TADDOL)-Derived Titanates: Differences between C2- and C1-symmetrical TADDOLs - facts, implications and generalizations，Helvetica Chimica Acta，1992年，Vol. 75，No. 7，pp. 2171-2209，DOI: 10.1002/hlca.19920750704
山中 宏 他，光学異性体の分離（季刊 化学総説 No.6），1989年，p. 2-11

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Publication number Publication date
WO2024014282A1 (ja) 2024-01-18
CN119487009A (zh) 2025-02-18
JPWO2024014282A1 (https=) 2024-01-18
EP4534531A1 (en) 2025-04-09
EP4534531A4 (en) 2025-12-03
US20260015329A1 (en) 2026-01-15

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