JP7685044B2 - 受容体ｔａｃ技術による膜結合タンパク質の下方制御 - Google Patents

受容体ｔａｃ技術による膜結合タンパク質の下方制御 Download PDF

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JP7685044B2
JP7685044B2 JP2023516810A JP2023516810A JP7685044B2 JP 7685044 B2 JP7685044 B2 JP 7685044B2 JP 2023516810 A JP2023516810 A JP 2023516810A JP 2023516810 A JP2023516810 A JP 2023516810A JP 7685044 B2 JP7685044 B2 JP 7685044B2
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JP2023542312A (ja
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周立
石峰
ミッシェル ハリス，
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Shandong Boan Biotechnology Co Ltd
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/418—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/31—Chimeric antigen receptors [CAR]
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JP2023516810A 2020-09-13 2021-09-13 受容体ｔａｃ技術による膜結合タンパク質の下方制御 Active JP7685044B2 (ja)

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US202063077658P 2020-09-13 2020-09-13
US63/077,658 2020-09-13
US202163144945P 2021-02-02 2021-02-02
US63/144,945 2021-02-02
US202163173476P 2021-04-11 2021-04-11
US63/173,476 2021-04-11
PCT/CN2021/117886 WO2022053036A1 (en) 2020-09-13 2021-09-13 Downregulation of membrane-bound proteins by receptor tac technology

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IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を治療するための方法
CN116063579B (zh) * 2022-11-17 2026-02-27 安徽医科大学 一种靶向人cd47的嵌合抗原受体、表达嵌合抗原受体的巨噬细胞及其应用
WO2024168276A2 (en) * 2023-02-09 2024-08-15 Cargo Therapeutics, Inc. Compositions and methods for immunotherapies
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Blood adv.，2018年，Vol. 2, No. 5，pp.517-528

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