JP2023542312A5 - - Google Patents
Info
- Publication number
- JP2023542312A5 JP2023542312A5 JP2023516810A JP2023516810A JP2023542312A5 JP 2023542312 A5 JP2023542312 A5 JP 2023542312A5 JP 2023516810 A JP2023516810 A JP 2023516810A JP 2023516810 A JP2023516810 A JP 2023516810A JP 2023542312 A5 JP2023542312 A5 JP 2023542312A5
- Authority
- JP
- Japan
- Prior art keywords
- transmembrane
- domain
- nucleic acid
- fusion protein
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063077658P | 2020-09-13 | 2020-09-13 | |
| US63/077,658 | 2020-09-13 | ||
| US202163144945P | 2021-02-02 | 2021-02-02 | |
| US63/144,945 | 2021-02-02 | ||
| US202163173476P | 2021-04-11 | 2021-04-11 | |
| US63/173,476 | 2021-04-11 | ||
| PCT/CN2021/117886 WO2022053036A1 (en) | 2020-09-13 | 2021-09-13 | Downregulation of membrane-bound proteins by receptor tac technology |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023542312A JP2023542312A (ja) | 2023-10-06 |
| JP2023542312A5 true JP2023542312A5 (https=) | 2024-06-26 |
| JP7685044B2 JP7685044B2 (ja) | 2025-05-28 |
Family
ID=80629753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516810A Active JP7685044B2 (ja) | 2020-09-13 | 2021-09-13 | 受容体ｔａｃ技術による膜結合タンパク質の下方制御 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230355764A1 (https=) |
| EP (1) | EP4178986A4 (https=) |
| JP (1) | JP7685044B2 (https=) |
| CN (1) | CN116368152A (https=) |
| WO (1) | WO2022053036A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| IL308258A (en) | 2021-05-05 | 2024-01-01 | Immatics Biotechnologies Gmbh | Bma031 antigen binding polypeptides |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
| CN116063579B (zh) * | 2022-11-17 | 2026-02-27 | 安徽医科大学 | 一种靶向人cd47的嵌合抗原受体、表达嵌合抗原受体的巨噬细胞及其应用 |
| WO2024168276A2 (en) * | 2023-02-09 | 2024-08-15 | Cargo Therapeutics, Inc. | Compositions and methods for immunotherapies |
| CN121419987A (zh) * | 2023-07-07 | 2026-01-27 | 南京传奇生物科技有限公司 | 蛋白质及其用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014093655A2 (en) * | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains |
| WO2017024318A1 (en) * | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| CA2937157A1 (en) * | 2016-07-25 | 2018-01-25 | Ucl Business Ltd | Protein-based t-cell receptor knockdown |
| US20200087681A1 (en) * | 2016-12-21 | 2020-03-19 | Ucl Business Plc | Therapeutic cells |
| JP2020505327A (ja) * | 2016-12-23 | 2020-02-20 | アルビナス・オペレーションズ・インコーポレイテッドＡｒｖｉｎａｓ Ｏｐｅｒａｔｉｏｎｓ， Ｉｎｃ． | Ｅｇｆｒタンパク質分解標的化キメラ分子およびその関連する使用方法 |
| GB201710620D0 (en) | 2017-07-03 | 2017-08-16 | Glaxosmithkline Intellectual Property Ltd | Targeted protein degradation |
| US20190038733A1 (en) * | 2017-08-10 | 2019-02-07 | National University Of Singapore | T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof |
| US12049482B2 (en) * | 2017-10-31 | 2024-07-30 | The Brigham And Women's Hospital, Inc. | Molecular switch-mediated control of engineered cells |
| CN112189051A (zh) * | 2018-03-16 | 2021-01-05 | 康奈尔大学 | 用工程化细菌泛素连接酶模拟物进行的广谱蛋白质组编辑 |
| EP3908291A4 (en) * | 2019-01-07 | 2023-01-11 | Dana-Farber Cancer Institute, Inc. | SMALL MOLECULAR DEGRADERS OF FKBP12 VIA RECRUITMENT OF THE VON HIPPEL-LINDAU E3 UBIQUITIN LIGASE (VHL) AND USE IN DTAG SYSTEMS |
| WO2020160419A1 (en) * | 2019-02-01 | 2020-08-06 | The Trustees Of Dartmouth College | Signaling platforms for chimeric antigen receptor t cells |
| CN113088495B (zh) * | 2020-01-09 | 2024-08-16 | 苏州方德门达新药开发有限公司 | 工程改造的t细胞、其制备及应用 |
-
2021
- 2021-09-13 CN CN202180062485.5A patent/CN116368152A/zh active Pending
- 2021-09-13 JP JP2023516810A patent/JP7685044B2/ja active Active
- 2021-09-13 WO PCT/CN2021/117886 patent/WO2022053036A1/en not_active Ceased
- 2021-09-13 US US18/026,063 patent/US20230355764A1/en active Pending
- 2021-09-13 EP EP21866088.4A patent/EP4178986A4/en active Pending
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