JP7650818B2 - 同種ｃａｒ ｔ細胞を製造する方法 - Google Patents

同種ｃａｒ ｔ細胞を製造する方法 Download PDF

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JP7650818B2
JP7650818B2 JP2021563069A JP2021563069A JP7650818B2 JP 7650818 B2 JP7650818 B2 JP 7650818B2 JP 2021563069 A JP2021563069 A JP 2021563069A JP 2021563069 A JP2021563069 A JP 2021563069A JP 7650818 B2 JP7650818 B2 JP 7650818B2
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car
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ディエゴ エイ バルガス－インハウステギ
トーマス チャールズ パーテル
バーブラ ジョンソン サス
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アロジーン セラピューティクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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JP2021563069A 2019-04-26 2020-04-24 同種ｃａｒ ｔ細胞を製造する方法 Active JP7650818B2 (ja)

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US201962839449P 2019-04-26 2019-04-26
US62/839,449 2019-04-26
PCT/US2020/029722 WO2020219812A1 (en) 2019-04-26 2020-04-24 Methods of manufacturing allogeneic car t cells

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JP2022529741A JP2022529741A (ja) 2022-06-23
JP2022529741A5 JP2022529741A5 (https=) 2023-05-01
JP7650818B2 true JP7650818B2 (ja) 2025-03-25

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US (2) US12163153B2 (https=)
EP (1) EP3959305A1 (https=)
JP (1) JP7650818B2 (https=)
KR (1) KR20220004028A (https=)
CN (1) CN113748201A (https=)
AU (1) AU2020261411B2 (https=)
BR (1) BR112021021349A2 (https=)
CA (1) CA3132509A1 (https=)
IL (1) IL287562B2 (https=)
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CA3158133A1 (en) * 2020-04-28 2021-11-04 Lyell Immunopharma, Inc. Methods for culturing cells
CN115039763A (zh) * 2022-07-15 2022-09-13 北京大学第三医院（北京大学第三临床医学院） 一种免疫细胞冻存液
CN118272305B (zh) * 2024-04-29 2025-04-08 深圳泽医细胞治疗集团有限公司 一种免疫细胞的培养基及其应用

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