JP7640474B2 - 血管性浮腫の治療 - Google Patents
血管性浮腫の治療 Download PDFInfo
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- JP7640474B2 JP7640474B2 JP2021571935A JP2021571935A JP7640474B2 JP 7640474 B2 JP7640474 B2 JP 7640474B2 JP 2021571935 A JP2021571935 A JP 2021571935A JP 2021571935 A JP2021571935 A JP 2021571935A JP 7640474 B2 JP7640474 B2 JP 7640474B2
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| GB201609607D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
| GB201719881D0 (en) | 2017-11-29 | 2018-01-10 | Kalvista Pharmaceuticals Ltd | Solid forms of plasma kallikrein inhibitor and salts thereof |
| WO2021028645A1 (en) | 2019-08-09 | 2021-02-18 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
| US20250281397A1 (en) | 2022-04-27 | 2025-09-11 | Kalvista Pharmaceuticals Limited | Formulations of a plasma kallikrein inhibitor |
| CN116003386B (zh) * | 2022-11-20 | 2024-03-26 | 药康众拓(北京)医药科技有限公司 | 一种氘代n-苄基吡啶酮吡唑甲酰胺类化合物、药物组合物和用途 |
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| JP2017535568A (ja) | 2014-11-27 | 2017-11-30 | カルビスタ・ファーマシューティカルズ・リミテッド | 血漿カリクレイン阻害剤としてのｎ−（（ヘタ）アリールメチル）−ヘテロアリール−カルボキサミド化合物 |
| WO2019106361A1 (en) | 2017-11-29 | 2019-06-06 | Kalvista Pharmaceuticals Limited | Dosage forms comprising a plasma kallikrein inhibitor |
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| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| GB9019558D0 (en) | 1990-09-07 | 1990-10-24 | Szelke Michael | Enzyme inhibitors |
| SE9301911D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | New peptide derivatives |
| US5589467A (en) | 1993-09-17 | 1996-12-31 | Novo Nordisk A/S | 2,5',N6-trisubstituted adenosine derivatives |
| GB0205527D0 (en) | 2002-03-08 | 2002-04-24 | Ferring Bv | Inhibitors |
| US7429604B2 (en) | 2004-06-15 | 2008-09-30 | Bristol Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| JP5322935B2 (ja) | 2006-07-31 | 2013-10-23 | アクティベサイト ファーマシューティカルズ インコーポレイティッド | 血漿カリクレインの阻害薬 |
| DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
| JP2013121919A (ja) | 2010-03-25 | 2013-06-20 | Astellas Pharma Inc | 血漿カリクレイン阻害剤 |
| EP2590945B1 (en) | 2010-07-07 | 2014-04-30 | The Medicines Company (Leipzig) GmbH | Serine protease inhibitors |
| US20130210809A1 (en) | 2010-07-14 | 2013-08-15 | Christelle Boléa | Novel 2-amino-4-pyrazolyl-thiazole derivatives and their use as allosteric modulators of metabotropic glutamate receptors |
| US9290485B2 (en) | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
| GB2494851A (en) | 2011-07-07 | 2013-03-27 | Kalvista Pharmaceuticals Ltd | Plasma kallikrein inhibitors |
| GB201300304D0 (en) | 2013-01-08 | 2013-02-20 | Kalvista Pharmaceuticals Ltd | Benzylamine derivatives |
| MY174018A (en) | 2013-05-23 | 2020-03-04 | Kalvista Pharmaceuticals Ltd | Heterocyclic derivates |
| EP2886107A1 (en) * | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Oral formulations of pyrrolydine derivatives |
| GB201609607D0 (en) * | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
| HUE057912T2 (hu) * | 2017-11-29 | 2022-06-28 | Kalvista Pharmaceuticals Ltd | Plazma kallikrein inhibitort tartalmazó dózisformák |
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| JP2017535568A (ja) | 2014-11-27 | 2017-11-30 | カルビスタ・ファーマシューティカルズ・リミテッド | 血漿カリクレイン阻害剤としてのｎ−（（ヘタ）アリールメチル）−ヘテロアリール−カルボキサミド化合物 |
| WO2019106361A1 (en) | 2017-11-29 | 2019-06-06 | Kalvista Pharmaceuticals Limited | Dosage forms comprising a plasma kallikrein inhibitor |
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| CL2023000699A1 (es) | 2023-10-30 |
| CN113993520A (zh) | 2022-01-28 |
| AU2020293616A1 (en) | 2022-01-27 |
| BR112021024447A2 (pt) | 2022-01-18 |
| PH12021552967A1 (en) | 2022-07-25 |
| EP3982961A1 (en) | 2022-04-20 |
| MX2021014558A (es) | 2022-04-06 |
| CL2021003243A1 (es) | 2022-09-30 |
| KR20220024221A (ko) | 2022-03-03 |
| CA3142220A1 (en) | 2020-12-17 |
| SG11202113375PA (en) | 2021-12-30 |
| IL288612A (en) | 2022-02-01 |
| JP2022537913A (ja) | 2022-08-31 |
| MA56188A (fr) | 2022-04-20 |
| US20220226293A1 (en) | 2022-07-21 |
| TW202112371A (zh) | 2021-04-01 |
| GB201910125D0 (en) | 2019-08-28 |
| CN118078821A (zh) | 2024-05-28 |
| WO2020249979A1 (en) | 2020-12-17 |
| AR119159A1 (es) | 2021-12-01 |
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