JP7620565B2 - 有効成分顆粒の連続製造のためのプロセス - Google Patents

有効成分顆粒の連続製造のためのプロセス Download PDF

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Publication number
JP7620565B2
JP7620565B2 JP2021560695A JP2021560695A JP7620565B2 JP 7620565 B2 JP7620565 B2 JP 7620565B2 JP 2021560695 A JP2021560695 A JP 2021560695A JP 2021560695 A JP2021560695 A JP 2021560695A JP 7620565 B2 JP7620565 B2 JP 7620565B2
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active ingredient
particles
process space
liquid
spray composition
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Japanese (ja)
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JPWO2020208201A5 (https=
JP2022528570A (ja
JP2022528570A5 (https=
Inventor
ノヴァク，ラインハルト
ペリンガー，ノルベルト
グラーヴェ，アネット
ヤコブ，ミハエル
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ADD Advanced Drug Delivery Technologies AG
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ADD Advanced Drug Delivery Technologies AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
JP2021560695A 2019-04-11 2020-04-09 有効成分顆粒の連続製造のためのプロセス Active JP7620565B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19168673.2A EP3721870A1 (de) 2019-04-11 2019-04-11 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
EP19168673.2 2019-04-11
PCT/EP2020/060277 WO2020208201A1 (de) 2019-04-11 2020-04-09 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats

Publications (4)

Publication Number Publication Date
JP2022528570A JP2022528570A (ja) 2022-06-14
JPWO2020208201A5 JPWO2020208201A5 (https=) 2023-04-14
JP2022528570A5 JP2022528570A5 (https=) 2023-04-14
JP7620565B2 true JP7620565B2 (ja) 2025-01-23

Family

ID=66105201

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JP2021560695A Active JP7620565B2 (ja) 2019-04-11 2020-04-09 有効成分顆粒の連続製造のためのプロセス

Country Status (10)

Country Link
US (1) US20220323361A1 (https=)
EP (2) EP3721870A1 (https=)
JP (1) JP7620565B2 (https=)
CN (1) CN114126591A (https=)
AU (1) AU2020272151B2 (https=)
BR (1) BR112021020320A2 (https=)
CA (1) CA3136529A1 (https=)
ES (1) ES3050631T3 (https=)
IL (1) IL287126B1 (https=)
WO (1) WO2020208201A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3721871A1 (de) * 2019-04-11 2020-10-14 ADD Advanced Drug Delivery Technologies, Ltd. Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
MX2023006016A (es) * 2020-11-24 2023-08-14 Nanoform Finland PLC Sistema, aparatos, dispositivos y metodos para producir particulas.
CN116422227B (zh) * 2022-12-09 2024-01-30 山东奥诺能源科技股份有限公司 一种流化床造粒机

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030039699A1 (en) 2001-03-07 2003-02-27 Yasushi Ochiai Method of manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
JP2017529381A (ja) 2014-10-13 2017-10-05 シージェイ ヘルスケア コーポレイションＣｊ Ｈｅａｌｔｈｃａｒｅ Ｃｏｒｐｏｒａｔｉｏｎ メトホルミン徐放性製剤及びその製造方法
WO2018034627A1 (en) 2016-08-18 2018-02-22 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Pharmaceutical composition of antidiabetic tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19514187C1 (de) * 1995-04-21 1996-05-15 Degussa Verfahren und Vorrichtung zur Herstellung von Granulaten durch Wirbelschicht-Sprühgranulation
US6117451A (en) 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
DE10004939C1 (de) 2000-02-05 2001-08-23 Lothar Moerl Steuerbare Gasanströmeinrichtung für Strahlschichtapparate
US6667054B2 (en) 2001-12-05 2003-12-23 Bernard Charles Sherman Metformin hydrochloride tablets
DE10322062A1 (de) 2003-05-15 2004-12-02 Glatt Ingenieurtechnik Gmbh Verfahren und Vorrichtung zum Aufbringen von Flüssigkeiten in eine Feststoffströmung eines Strahlschichtapparates
ES2374191T3 (es) 2003-06-11 2012-02-14 Glatt Ingenieurtechnik Gmbh Procedimiento de preparación de granulados de enzimas y granulados de enzimas así obtenidos.
CA2572549A1 (en) * 2004-07-01 2006-01-12 Warner-Lambert Company Llc Preparation of pharmaceutical compositions containing nanoparticles
DE102007012105A1 (de) * 2007-03-13 2008-09-18 Add Advanced Drug Delivery Technologies Ltd. Pellets enthaltend pharmazeutische Substanz, Verfahren zu deren Herstellung und deren Verwendung
EP2590631B1 (en) * 2010-07-06 2016-10-26 Janssen Pharmaceutica NV Formulation for co-therapy treatment of diabetes
WO2013143688A1 (en) * 2012-03-26 2013-10-03 Glatt Ag Taste-masked ibuprofen granules
JP5922310B2 (ja) * 2013-07-25 2016-05-24 株式会社三和化学研究所 医薬製剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030039699A1 (en) 2001-03-07 2003-02-27 Yasushi Ochiai Method of manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
JP2017529381A (ja) 2014-10-13 2017-10-05 シージェイ ヘルスケア コーポレイションＣｊ Ｈｅａｌｔｈｃａｒｅ Ｃｏｒｐｏｒａｔｉｏｎ メトホルミン徐放性製剤及びその製造方法
WO2018034627A1 (en) 2016-08-18 2018-02-22 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Pharmaceutical composition of antidiabetic tablet

Also Published As

Publication number Publication date
EP3721870A1 (de) 2020-10-14
EP3952843B1 (de) 2025-08-06
CN114126591A (zh) 2022-03-01
IL287126B1 (en) 2026-01-01
CA3136529A1 (en) 2020-10-15
JP2022528570A (ja) 2022-06-14
US20220323361A1 (en) 2022-10-13
AU2020272151A1 (en) 2021-12-09
IL287126A (en) 2022-01-01
ES3050631T3 (en) 2025-12-22
EP3952843A1 (de) 2022-02-16
WO2020208201A1 (de) 2020-10-15
BR112021020320A2 (pt) 2021-12-14
AU2020272151B2 (en) 2025-07-03

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