JP7605852B2 - クラスiiのv型crispr系 - Google Patents

クラスiiのv型crispr系 Download PDF

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JP7605852B2
JP7605852B2 JP2022553203A JP2022553203A JP7605852B2 JP 7605852 B2 JP7605852 B2 JP 7605852B2 JP 2022553203 A JP2022553203 A JP 2022553203A JP 2022553203 A JP2022553203 A JP 2022553203A JP 7605852 B2 JP7605852 B2 JP 7605852B2
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sequence
endonuclease
seq
engineered
guide
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JPWO2021178933A5 (https=
JP2023517041A (ja
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トーマス,ブライアン
ブラウン,クリストファー
デヴォート,オードラ
バターフィールド,クリスティーナ
アレクサンダー,リサ
エス.エー. ゴルツマン,ダニエラ
アルバース,ジャスティン
ブルックス,アラン
コスト,グレッグ
テモーチェ-ディアス,モライマ
カステル,シンディ
ラモット,レベッカ
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メタゲノミ,インク.
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    • C12N15/90Stable introduction of foreign DNA into chromosome
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    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1068Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
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    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C07K2319/00Fusion polypeptide
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    • C07K2319/09Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2800/00Nucleic acids vectors
    • C12N2800/80Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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JP2022553203A 2020-03-06 2021-03-06 クラスiiのv型crispr系 Active JP7605852B2 (ja)

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US202062986477P 2020-03-06 2020-03-06
US62/986,477 2020-03-06
US202063022276P 2020-05-08 2020-05-08
US63/022,276 2020-05-08
US202063045815P 2020-06-29 2020-06-29
US63/045,815 2020-06-29
US202063068316P 2020-08-20 2020-08-20
US63/068,316 2020-08-20
US202063069699P 2020-08-24 2020-08-24
US63/069,699 2020-08-24
US202063116157P 2020-11-19 2020-11-19
US63/116,157 2020-11-19
PCT/US2021/021259 WO2021178933A2 (en) 2020-03-06 2021-03-06 Class ii, type v crispr systems

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EP (1) EP4114932A4 (https=)
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KR (2) KR102647766B1 (https=)
CN (1) CN116096876A (https=)
AU (2) AU2021231074C1 (https=)
CA (1) CA3174557A1 (https=)
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