CN116096876A - Ii类v型crispr系统 - Google Patents

Ii类v型crispr系统 Download PDF

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Publication number
CN116096876A
CN116096876A CN202180033688.1A CN202180033688A CN116096876A CN 116096876 A CN116096876 A CN 116096876A CN 202180033688 A CN202180033688 A CN 202180033688A CN 116096876 A CN116096876 A CN 116096876A
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sequence
guide rna
endonuclease
engineered
seq
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Inventor
布莱恩·托马斯
克利斯多佛·布朗
奥德拉·德沃托
克里斯蒂娜·布特弗尔德
利萨·亚历山大
丹妮拉·S·A·戈尔茨曼
贾斯汀·阿尔伯斯
亚伦·布鲁克斯
格雷格·科斯特
莫拉伊玛·特莫彻-迪亚兹
辛迪·卡斯泰勒
丽贝卡·拉莫特
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Macrogenomics
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Macrogenomics
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    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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CN202180033688.1A 2020-03-06 2021-03-06 Ii类v型crispr系统 Pending CN116096876A (zh)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202062986477P 2020-03-06 2020-03-06
US62/986,477 2020-03-06
US202063022276P 2020-05-08 2020-05-08
US63/022,276 2020-05-08
US202063045815P 2020-06-29 2020-06-29
US63/045,815 2020-06-29
US202063068316P 2020-08-20 2020-08-20
US63/068,316 2020-08-20
US202063069699P 2020-08-24 2020-08-24
US63/069,699 2020-08-24
US202063116157P 2020-11-19 2020-11-19
US63/116,157 2020-11-19
PCT/US2021/021259 WO2021178933A2 (en) 2020-03-06 2021-03-06 Class ii, type v crispr systems

Publications (1)

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CN116096876A true CN116096876A (zh) 2023-05-09

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CN202180033688.1A Pending CN116096876A (zh) 2020-03-06 2021-03-06 Ii类v型crispr系统

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US (3) US11713471B2 (https=)
EP (1) EP4114932A4 (https=)
JP (2) JP7605852B2 (https=)
KR (2) KR102647766B1 (https=)
CN (1) CN116096876A (https=)
AU (2) AU2021231074C1 (https=)
CA (1) CA3174557A1 (https=)
GB (2) GB2617658B (https=)
MX (1) MX2022011039A (https=)
WO (1) WO2021178933A2 (https=)

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CN118773168A (zh) * 2023-11-24 2024-10-15 华智生物技术有限公司 CRISPR/Cas效应蛋白及系统
CN118773168B (zh) * 2023-11-24 2025-07-25 华智生物技术有限公司 CRISPR/Cas效应蛋白HT001及系统与应用

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