JP7603612B2 - 治療法 - Google Patents
治療法 Download PDFInfo
- Publication number
- JP7603612B2 JP7603612B2 JP2021563064A JP2021563064A JP7603612B2 JP 7603612 B2 JP7603612 B2 JP 7603612B2 JP 2021563064 A JP2021563064 A JP 2021563064A JP 2021563064 A JP2021563064 A JP 2021563064A JP 7603612 B2 JP7603612 B2 JP 7603612B2
- Authority
- JP
- Japan
- Prior art keywords
- seq
- protein
- nomacopan
- substituted
- asn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1905810.6 | 2019-04-25 | ||
| GBGB1905810.6A GB201905810D0 (en) | 2019-04-25 | 2019-04-25 | Method of treatment |
| GB2000955.1 | 2020-01-22 | ||
| GBGB2000955.1A GB202000955D0 (en) | 2019-04-25 | 2020-01-22 | Method of treatment |
| PCT/EP2020/055741 WO2020216513A1 (en) | 2019-04-25 | 2020-03-04 | Method of treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022530068A JP2022530068A (ja) | 2022-06-27 |
| JP2022530068A5 JP2022530068A5 (https=) | 2023-03-13 |
| JP7603612B2 true JP7603612B2 (ja) | 2024-12-20 |
Family
ID=66810336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563064A Active JP7603612B2 (ja) | 2019-04-25 | 2020-03-04 | 治療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220211810A1 (https=) |
| EP (1) | EP3958974A1 (https=) |
| JP (1) | JP7603612B2 (https=) |
| KR (1) | KR20220018963A (https=) |
| CN (1) | CN114072206B (https=) |
| AU (1) | AU2020263709A1 (https=) |
| CA (1) | CA3137240A1 (https=) |
| GB (2) | GB201905810D0 (https=) |
| IL (1) | IL287250A (https=) |
| WO (1) | WO2020216513A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202218084D0 (en) | 2022-12-01 | 2023-01-18 | Volution Immuno Pharmaceuticals Sa | Fusion proteins |
| WO2024238859A1 (en) * | 2023-05-16 | 2024-11-21 | Regenxbio Inc. | Vectorized c5 inhibitor agents and administration thereof |
| GB202408081D0 (en) | 2024-06-06 | 2024-07-24 | Volution Immuno Pharmaceuticals Sa | Methods of removing impurities |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010521194A (ja) | 2007-03-22 | 2010-06-24 | ノバルティス アーゲー | C5抗原およびその使用 |
| JP2018530574A (ja) | 2015-10-07 | 2018-10-18 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 患者の加齢黄斑変性を治療する方法 |
| WO2018193120A1 (en) | 2017-04-21 | 2018-10-25 | Volution Immuno Pharmaceuticals Sa | Coversin for the treatment of cicatrising eye inflammatory disorders |
| WO2018193121A1 (en) | 2017-04-21 | 2018-10-25 | Volution Immuno Pharmaceuticals Sa | Coversin variants lacking c5 binding |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1629098B1 (en) | 2003-06-02 | 2009-04-01 | Varleigh Limited | Complement inhibitors from ticks |
| GB0518443D0 (en) * | 2005-09-09 | 2005-10-19 | Evolutec Ltd | Method of treating myasthenia gravis |
| GB0617734D0 (en) * | 2006-09-08 | 2006-10-18 | Evolutec Ltd | Method of treating peripheral nerve disorders |
| PL2061501T3 (pl) | 2006-09-08 | 2016-01-29 | Volution Immuno Pharmaceuticals Sa | Sposób leczenia zaburzeń oddechowych |
| SI2173890T1 (sl) * | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
| GB0802116D0 (en) * | 2008-02-05 | 2008-03-12 | Natural Enviromental Res Counc | Treatment |
| GB0906779D0 (en) * | 2009-04-20 | 2009-06-03 | Natural Environment Res Council | Composition |
| JP5840623B2 (ja) | 2010-01-08 | 2016-01-06 | ヴォリューション イミュノ ファーマシューティカルズ エスエイ | 気道のウイルス感染症の治療に用いるev576 |
| GB201401453D0 (en) * | 2014-01-28 | 2014-03-12 | Univ Birmingham | Transmucosal and transepithelial drug delivery system |
| GB201410116D0 (en) * | 2014-06-06 | 2014-07-23 | Volution Immuno Pharmaceuticals Sa | Method of treatment |
| CA2988313A1 (en) | 2015-06-08 | 2016-12-15 | Volution Immuno Pharmaceuticals Sa | Ornithodoros moubata complement inhibitor for use in the treatment of acute graft versus host disease |
| SG11201811491YA (en) * | 2016-06-27 | 2019-01-30 | Achillion Pharmaceuticals Inc | Quinazoline and indole compounds to treat medical disorders |
| AU2018226872A1 (en) * | 2017-03-03 | 2019-09-05 | Macregen, Inc. | Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents |
| US11730792B2 (en) * | 2017-04-21 | 2023-08-22 | Volution Immuno Pharmaceuticals Sa | Coversin (OmCI) for the treatment of autoimmune blistering diseases: bullous pemphigoid (BP) and epidermolysis bullosa acquisita (EBA) |
| JP7629394B2 (ja) * | 2018-09-10 | 2025-02-13 | ヴォリューション イミュノ ファーマシューティカルズ エスエイ | リウマチ性疾患の治療に使用するためのコバーシン |
| US20220370556A1 (en) * | 2019-09-27 | 2022-11-24 | Volution Immuno Pharmaceuticals Sa | Method of Treatment |
-
2019
- 2019-04-25 GB GBGB1905810.6A patent/GB201905810D0/en not_active Ceased
-
2020
- 2020-01-22 GB GBGB2000955.1A patent/GB202000955D0/en not_active Ceased
- 2020-03-04 CA CA3137240A patent/CA3137240A1/en active Pending
- 2020-03-04 WO PCT/EP2020/055741 patent/WO2020216513A1/en not_active Ceased
- 2020-03-04 US US17/604,509 patent/US20220211810A1/en not_active Abandoned
- 2020-03-04 JP JP2021563064A patent/JP7603612B2/ja active Active
- 2020-03-04 EP EP20710849.9A patent/EP3958974A1/en not_active Withdrawn
- 2020-03-04 KR KR1020217037686A patent/KR20220018963A/ko not_active Ceased
- 2020-03-04 AU AU2020263709A patent/AU2020263709A1/en not_active Abandoned
- 2020-03-04 CN CN202080046367.0A patent/CN114072206B/zh active Active
-
2021
- 2021-10-13 IL IL287250A patent/IL287250A/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010521194A (ja) | 2007-03-22 | 2010-06-24 | ノバルティス アーゲー | C5抗原およびその使用 |
| JP2018530574A (ja) | 2015-10-07 | 2018-10-18 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 患者の加齢黄斑変性を治療する方法 |
| WO2018193120A1 (en) | 2017-04-21 | 2018-10-25 | Volution Immuno Pharmaceuticals Sa | Coversin for the treatment of cicatrising eye inflammatory disorders |
| WO2018193121A1 (en) | 2017-04-21 | 2018-10-25 | Volution Immuno Pharmaceuticals Sa | Coversin variants lacking c5 binding |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022530068A (ja) | 2022-06-27 |
| GB202000955D0 (en) | 2020-03-04 |
| EP3958974A1 (en) | 2022-03-02 |
| US20220211810A1 (en) | 2022-07-07 |
| CN114072206A (zh) | 2022-02-18 |
| CA3137240A1 (en) | 2020-10-29 |
| AU2020263709A1 (en) | 2021-12-23 |
| GB201905810D0 (en) | 2019-06-05 |
| WO2020216513A1 (en) | 2020-10-29 |
| IL287250A (en) | 2021-12-01 |
| CN114072206B (zh) | 2024-11-08 |
| KR20220018963A (ko) | 2022-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110896606B (zh) | 用于治疗自身免疫性水疱病的coversin | |
| US20180133288A1 (en) | Pharmaceutical composition for preventing and treating eye diseases, containing, as active ingredient, fusion protein in which tissue-penetrating peptide and anti-vascular endothelial growth factor preparation are fused | |
| JP7603612B2 (ja) | 治療法 | |
| US11596667B2 (en) | Method for treating or preventing idiopathic polypoidal choroidal vasculopathy (IPCV) | |
| JP2018535696A (ja) | 遺伝子構築物 | |
| US9260506B2 (en) | Treatment of retinal disorders with recombinant T cell receptor ligand (RTL) | |
| CA2666843C (en) | Treatment of age-related macular degeneration and other diseases of the eye | |
| JP2020517643A (ja) | 瘢痕性眼炎症障害の治療のためのコバーシン | |
| EP3675889A2 (en) | Angio-3 for treatment of retinal angiogenic diseases | |
| AU2019468121A1 (en) | Method of treatment of hematopoietic stem cell transplant associated thrombotic microangiopathy (HSCT-TMA) | |
| WO2005118799A1 (en) | Ovine hyaluronidase | |
| WO2013005603A9 (ja) | 結膜におけるアレルギー性炎症の予防及び/又は治療剤 | |
| JP6944463B2 (ja) | 眼疾患の治療のための組成物及び方法 | |
| AU2012385960A1 (en) | Method of treating hyperglycemic disorders using apolipoprotein AIV | |
| WO2024115767A1 (en) | Nomacopan-pas fusion proteins | |
| WO2025036488A9 (en) | Methods of treating age-related macular degeneration and diabetic macular edema |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A80 | Written request to apply exceptions to lack of novelty of invention |
Free format text: JAPANESE INTERMEDIATE CODE: A80 Effective date: 20220121 Free format text: JAPANESE INTERMEDIATE CODE: A801 Effective date: 20220120 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230303 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230303 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20240124 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240206 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20240409 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240801 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20241112 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20241210 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7603612 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |