JP7593619B2 - ヘロイン依存症及び物質使用障害のためのマジンドール治療 - Google Patents

ヘロイン依存症及び物質使用障害のためのマジンドール治療 Download PDF

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JP7593619B2
JP7593619B2 JP2020513594A JP2020513594A JP7593619B2 JP 7593619 B2 JP7593619 B2 JP 7593619B2 JP 2020513594 A JP2020513594 A JP 2020513594A JP 2020513594 A JP2020513594 A JP 2020513594A JP 7593619 B2 JP7593619 B2 JP 7593619B2
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mazindol
heroin
drug
group
composition
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JP2020533295A (ja
JP2020533295A5 (https=
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アレクサンダー シー. ツヴァイヤー
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エヌエルエス-1 ファルマ アーゲー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2020513594A 2017-09-07 2018-09-06 ヘロイン依存症及び物質使用障害のためのマジンドール治療 Active JP7593619B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762555469P 2017-09-07 2017-09-07
US62/555,469 2017-09-07
PCT/IB2018/001138 WO2019058172A1 (en) 2017-09-07 2018-09-06 MAZINDOLE TREATMENT FOR HEROID DEPENDENCE AND DISORDER RELATED TO THE USE OF PSYCHOACTIVE SUBSTANCES

Publications (3)

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JP2020533295A JP2020533295A (ja) 2020-11-19
JP2020533295A5 JP2020533295A5 (https=) 2021-08-19
JP7593619B2 true JP7593619B2 (ja) 2024-12-03

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ID=64316589

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JP2020513594A Active JP7593619B2 (ja) 2017-09-07 2018-09-06 ヘロイン依存症及び物質使用障害のためのマジンドール治療

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US (1) US11596622B2 (https=)
EP (1) EP3678661A1 (https=)
JP (1) JP7593619B2 (https=)
KR (1) KR20200085730A (https=)
CN (1) CN111343979A (https=)
BR (1) BR112020004506A2 (https=)
CA (1) CA3074054A1 (https=)
MX (1) MX2020002560A (https=)
WO (1) WO2019058172A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991011184A1 (en) 1990-02-05 1991-08-08 Yale University Dopamine uptake inhibitors in reducing substance abuse and/or craving
JP2003504303A (ja) 1998-12-02 2003-02-04 ピーター・スターリング・ミュラー 器質性障害から派生する障害の治療
JP2010529022A (ja) 2007-05-29 2010-08-26 ヴェロサイエンス・エルエルシー メタボリックシンドローム、2型糖尿病、肥満又は糖尿病前症の治療的処置方法
JP2010537990A (ja) 2007-08-27 2010-12-09 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール中毒および薬物嗜癖の処置のための医薬の組み合わせ
JP2013523757A (ja) 2010-03-31 2013-06-17 スパーナス ファーマシューティカルズ インコーポレイテッド マジンドールの製剤
JP2015199687A (ja) 2014-04-09 2015-11-12 日本製粉株式会社 抗肥満薬の効果を向上させる組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2899476B1 (fr) 2006-04-11 2008-07-04 Assist Publ Hopitaux De Paris Association du mazindol dans le traitement du deficit de l'attention/hyperactivite
US9687445B2 (en) * 2012-04-12 2017-06-27 Lts Lohmann Therapie-Systeme Ag Oral film containing opiate enteric-release beads
ES2884973T3 (es) 2016-03-09 2021-12-13 Nls Pharmaceutics Ag Comprimido multicapa de mazindol de IR/SR y su utilización para el tratamiento del trastorno por déficit de atención/hiperactividad (ADHD)

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991011184A1 (en) 1990-02-05 1991-08-08 Yale University Dopamine uptake inhibitors in reducing substance abuse and/or craving
JP2003504303A (ja) 1998-12-02 2003-02-04 ピーター・スターリング・ミュラー 器質性障害から派生する障害の治療
JP2010529022A (ja) 2007-05-29 2010-08-26 ヴェロサイエンス・エルエルシー メタボリックシンドローム、2型糖尿病、肥満又は糖尿病前症の治療的処置方法
JP2010537990A (ja) 2007-08-27 2010-12-09 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール中毒および薬物嗜癖の処置のための医薬の組み合わせ
JP2013523757A (ja) 2010-03-31 2013-06-17 スパーナス ファーマシューティカルズ インコーポレイテッド マジンドールの製剤
JP2015199687A (ja) 2014-04-09 2015-11-12 日本製粉株式会社 抗肥満薬の効果を向上させる組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
European Journal of Pharmacology 340(1997),249-258
Neuroscience and Biobehavioral Reviews 37(2013),2081-2086

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Publication number Publication date
CA3074054A1 (en) 2019-03-28
US11596622B2 (en) 2023-03-07
EP3678661A1 (en) 2020-07-15
US20210161865A1 (en) 2021-06-03
JP2020533295A (ja) 2020-11-19
MX2020002560A (es) 2020-07-13
WO2019058172A1 (en) 2019-03-28
BR112020004506A2 (pt) 2020-09-15
CN111343979A (zh) 2020-06-26
KR20200085730A (ko) 2020-07-15

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