JP7546599B2 - 関節炎性疾患の組み合わせ療法 - Google Patents

関節炎性疾患の組み合わせ療法 Download PDF

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JP7546599B2
JP7546599B2 JP2021566199A JP2021566199A JP7546599B2 JP 7546599 B2 JP7546599 B2 JP 7546599B2 JP 2021566199 A JP2021566199 A JP 2021566199A JP 2021566199 A JP2021566199 A JP 2021566199A JP 7546599 B2 JP7546599 B2 JP 7546599B2
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JP2022531906A (ja
JP2022531906A5 (https=
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ジョナッセン，トーマス，エンゲルブレット，ノードキルド
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シナクト ファーマ エーピーエス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021566199A 2019-05-10 2020-05-07 関節炎性疾患の組み合わせ療法 Active JP7546599B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19173734 2019-05-10
EP19173734.5 2019-05-10
PCT/EP2020/062711 WO2020229297A1 (en) 2019-05-10 2020-05-07 Combination treatment of arthritic disease

Publications (3)

Publication Number Publication Date
JP2022531906A JP2022531906A (ja) 2022-07-12
JP2022531906A5 JP2022531906A5 (https=) 2023-05-15
JP7546599B2 true JP7546599B2 (ja) 2024-09-06

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JP2021566199A Active JP7546599B2 (ja) 2019-05-10 2020-05-07 関節炎性疾患の組み合わせ療法

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US (2) US12303489B2 (https=)
EP (2) EP3773558B1 (https=)
JP (1) JP7546599B2 (https=)
KR (1) KR20220006551A (https=)
CN (1) CN113795250B (https=)
AU (1) AU2020273479B2 (https=)
BR (1) BR112021022397A2 (https=)
CA (1) CA3139000A1 (https=)
CY (1) CY1125564T1 (https=)
DK (1) DK3773558T3 (https=)
ES (2) ES2927294T3 (https=)
HU (1) HUE059638T2 (https=)
IL (1) IL287904B2 (https=)
LT (1) LT3773558T (https=)
MX (1) MX2021013296A (https=)
PL (1) PL3773558T3 (https=)
PT (1) PT3773558T (https=)
SG (1) SG11202111821SA (https=)
SI (1) SI3773558T1 (https=)
WO (1) WO2020229297A1 (https=)
ZA (1) ZA202108219B (https=)

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LT3773558T (lt) 2019-05-10 2022-09-12 Synact Pharma Aps Kompleksinis artrito gydymas
CN120617247A (zh) * 2020-03-31 2025-09-12 西奈克制药有限公司 症状性病毒性疾病的治疗
WO2022223778A1 (en) 2021-04-23 2022-10-27 Helmholtz-Zentrum für Infektionsforschung GmbH Citraconic acid and derivatives thereof for use as a medicament
EP4359076B1 (en) 2021-06-21 2025-08-06 SynAct Pharma ApS Phenyl pyrrole aminoguanidine salts and formulations
US20250032449A1 (en) * 2021-11-29 2025-01-30 Synact Pharma Aps Treatment of rheumatoid arthritis
WO2023218048A1 (en) * 2022-05-12 2023-11-16 Synact Pharma Aps Resomelagon and its derivatives for the treatment of cardiovascular disease, hypertension and atherosclerosis
CN120584099A (zh) * 2022-12-21 2025-09-02 西奈克制药有限公司 苯基吡咯肼甲脒化合物的多晶型物
WO2025124760A1 (en) 2023-12-11 2025-06-19 Synact Pharma Aps Treatment of subpopulation of patients with rheumatoid arthritis
WO2026049571A1 (ko) * 2024-08-29 2026-03-05 루다큐어 주식회사 통증 치료용 조성물

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Publication number Publication date
US20220211666A1 (en) 2022-07-07
LT3773558T (lt) 2022-09-12
IL287904A (en) 2022-01-01
US12303489B2 (en) 2025-05-20
CN113795250B (zh) 2024-10-15
KR20220006551A (ko) 2022-01-17
JP2022531906A (ja) 2022-07-12
ES3041907T3 (en) 2025-11-17
PT3773558T (pt) 2022-09-13
CY1125564T1 (el) 2026-02-25
EP3773558A1 (en) 2021-02-17
EP4119140A1 (en) 2023-01-18
US20250387365A1 (en) 2025-12-25
ES2927294T3 (es) 2022-11-04
IL287904B2 (en) 2026-03-01
SI3773558T1 (sl) 2022-11-30
AU2020273479A1 (en) 2021-12-23
DK3773558T3 (da) 2022-09-19
EP4119140C0 (en) 2025-06-25
EP4119140B1 (en) 2025-06-25
IL287904B1 (en) 2025-11-01
WO2020229297A1 (en) 2020-11-19
PL3773558T3 (pl) 2022-10-03
HUE059638T2 (hu) 2022-12-28
CA3139000A1 (en) 2020-11-19
SG11202111821SA (en) 2021-11-29
ZA202108219B (en) 2023-03-29
EP3773558B1 (en) 2022-06-15
AU2020273479B2 (en) 2025-02-27
MX2021013296A (es) 2021-12-15
CN113795250A (zh) 2021-12-14
BR112021022397A2 (pt) 2021-12-28

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