JP7512278B2 - 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定 - Google Patents

肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定 Download PDF

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JP7512278B2
JP7512278B2 JP2021530259A JP2021530259A JP7512278B2 JP 7512278 B2 JP7512278 B2 JP 7512278B2 JP 2021530259 A JP2021530259 A JP 2021530259A JP 2021530259 A JP2021530259 A JP 2021530259A JP 7512278 B2 JP7512278 B2 JP 7512278B2
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アラーウィ,ハティム
ピー. リドガード,グラハム
ギアクモプロス,マリア
エー. アールクイスト,デビッド
アール. テイラー,ウィリアム
マホーニー,ダグラス
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    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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JP2021530259A 2018-11-27 2019-11-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定 Active JP7512278B2 (ja)

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JP2024103130A JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

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US201862771965P 2018-11-27 2018-11-27
US62/771,965 2018-11-27
PCT/US2019/063401 WO2020112869A1 (en) 2018-11-27 2019-11-26 Characterizing methylated dna, rna, and proteins in the detection of lung neoplasia

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JP2022513658A JP2022513658A (ja) 2022-02-09
JPWO2020112869A5 JPWO2020112869A5 (enrdf_load_stackoverflow) 2022-12-06
JP7512278B2 true JP7512278B2 (ja) 2024-07-08

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JP2024103130A Pending JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

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US (1) US20220136058A1 (enrdf_load_stackoverflow)
EP (1) EP3886878A4 (enrdf_load_stackoverflow)
JP (2) JP7512278B2 (enrdf_load_stackoverflow)
KR (1) KR20210099044A (enrdf_load_stackoverflow)
CN (1) CN113423410A (enrdf_load_stackoverflow)
AU (1) AU2019389008A1 (enrdf_load_stackoverflow)
BR (1) BR112021009795A2 (enrdf_load_stackoverflow)
CA (1) CA3119329A1 (enrdf_load_stackoverflow)
MX (1) MX2021005963A (enrdf_load_stackoverflow)
WO (1) WO2020112869A1 (enrdf_load_stackoverflow)

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US8673555B2 (en) 2008-02-15 2014-03-18 Mayo Foundation For Medical Education And Research Detecting neoplasm
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
US8916344B2 (en) 2010-11-15 2014-12-23 Exact Sciences Corporation Methylation assay
EP3126529B1 (en) 2014-03-31 2020-05-27 Mayo Foundation for Medical Education and Research Detecting colorectal neoplasm
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
EP3274440A4 (en) 2015-03-27 2019-03-06 Exact Sciences Corporation Detecting esophageal disorders
EP3368686A1 (en) 2015-10-30 2018-09-05 Exact Sciences Development Company, LLC Multiplex amplification detection assay and isolation and detection of dna from plasma
US10385406B2 (en) 2016-05-05 2019-08-20 Exact Sciences Development Company, Llc Detection of lung neoplasia by analysis of methylated DNA
CN110475875B (zh) 2017-01-27 2024-06-25 精密科学公司 通过分析甲基化dna检测结肠瘤形成
KR20250117473A (ko) 2017-11-30 2025-08-04 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 유방암 검출방법
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
JP2022546504A (ja) * 2019-08-27 2022-11-04 エグザクト サイエンシーズ コーポレーション 肺新生物形成を有する疑いのある対象におけるメチル化されたdna、rna、及びタンパク質の特性決定
US11898199B2 (en) 2019-11-11 2024-02-13 Universal Diagnostics, S.A. Detection of colorectal cancer and/or advanced adenomas
WO2022002424A1 (en) 2020-06-30 2022-01-06 Universal Diagnostics, S.L. Systems and methods for detection of multiple cancer types
EP3945135A1 (en) * 2020-07-27 2022-02-02 Les Laboratoires Servier Biomarkers for diagnosing and monitoring lung cancer
WO2022165247A1 (en) * 2021-01-29 2022-08-04 Mayo Foundation For Medical Education And Research Detecting the presence or absence of multiple types of cancer
CN115505640A (zh) * 2021-06-22 2022-12-23 上海鹍远生物科技股份有限公司 检测肺癌的dna甲基化标志物及应用
CN115725734B (zh) * 2022-08-10 2023-10-13 人和未来生物科技(长沙)有限公司 Znf781基因在制备宫颈癌诊断试剂中的应用

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US20110318738A1 (en) * 2008-12-23 2011-12-29 University Of Utah Research Foundation Identification and regulation of a novel dna demethylase system
CN104066851A (zh) * 2011-09-30 2014-09-24 基因泰克公司 肿瘤或肿瘤细胞中上皮或间充质表型的诊断性甲基化标志物和对egfr激酶抑制剂的响应
WO2013070950A1 (en) * 2011-11-08 2013-05-16 University Of Southern California Identification of a dna methylation marker for blood-based detection of ovarian cancer
US9546403B1 (en) * 2011-12-14 2017-01-17 University Of Utah Research Foundation Substrate for methylated DNA testing
WO2016094813A1 (en) * 2014-12-12 2016-06-16 Exact Sciences Corporation Compositions and methods for performing methylation detection assays
US10385406B2 (en) * 2016-05-05 2019-08-20 Exact Sciences Development Company, Llc Detection of lung neoplasia by analysis of methylated DNA
WO2017223216A1 (en) * 2016-06-21 2017-12-28 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
WO2018017740A1 (en) * 2016-07-19 2018-01-25 Exact Sciences Development Company, Llc Methylated control dna

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US20220136058A1 (en) 2022-05-05
JP2024123233A (ja) 2024-09-10
BR112021009795A2 (pt) 2021-08-17
CN113423410A (zh) 2021-09-21
JP2022513658A (ja) 2022-02-09
EP3886878A1 (en) 2021-10-06
CA3119329A1 (en) 2020-06-04
MX2021005963A (es) 2021-08-24
KR20210099044A (ko) 2021-08-11
WO2020112869A1 (en) 2020-06-04
EP3886878A4 (en) 2022-11-02
AU2019389008A1 (en) 2021-06-03

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