JP7504097B2 - Ｃｄｋ４／６阻害剤に耐性の癌を治療するための方法 - Google Patents

Ｃｄｋ４／６阻害剤に耐性の癌を治療するための方法 Download PDF

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JP7504097B2
JP7504097B2 JP2021531818A JP2021531818A JP7504097B2 JP 7504097 B2 JP7504097 B2 JP 7504097B2 JP 2021531818 A JP2021531818 A JP 2021531818A JP 2021531818 A JP2021531818 A JP 2021531818A JP 7504097 B2 JP7504097 B2 JP 7504097B2
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パテル，ヒティシャ
ビハニ，ティール
アールト，ハイク
タオ，ニアンジュン
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ラジウス ファーマシューティカルズ，インコーポレイテッド
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JP2021531818A 2018-12-06 2019-12-06 Ｃｄｋ４／６阻害剤に耐性の癌を治療するための方法 Active JP7504097B2 (ja)

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US201862776323P 2018-12-06 2018-12-06
US62/776,323 2018-12-06
PCT/US2019/065005 WO2020118213A1 (en) 2018-12-06 2019-12-06 Methods for treating cancer resistant to cdk4/6 inhibitors

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JP2022511498A JP2022511498A (ja) 2022-01-31
JPWO2020118213A5 JPWO2020118213A5 (enExample) 2022-12-19
JP7504097B2 true JP7504097B2 (ja) 2024-06-21

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US (2) US20210330612A1 (enExample)
EP (1) EP3890834A1 (enExample)
JP (1) JP7504097B2 (enExample)
KR (1) KR20210100137A (enExample)
CN (2) CN113164779A (enExample)
AU (1) AU2019395093B2 (enExample)
BR (1) BR112021010110A2 (enExample)
CA (1) CA3121930A1 (enExample)
EA (1) EA202191283A1 (enExample)
IL (1) IL283659A (enExample)
JO (1) JOP20210137A1 (enExample)
MA (1) MA54388A (enExample)
MX (1) MX2021006411A (enExample)
PH (1) PH12021551319A1 (enExample)
SG (1) SG11202105531XA (enExample)
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RS64976B1 (sr) 2016-12-01 2024-01-31 Arvinas Operations Inc Derivati tetrahidronaftalena i tetrahidroizohinolina kao degradatori estrogenih receptora
CN114667147B (zh) 2019-08-26 2024-09-06 阿尔维纳斯运营股份有限公司 用四氢萘衍生物作为雌激素受体降解剂的治疗乳腺癌的方法
CA3202592A1 (en) * 2020-12-14 2022-06-23 Arvinas Operations, Inc. Methods of treating breast cancer with tetrahydronaphthalene derivatives as estrogen receptor degraders
GB202116745D0 (en) * 2021-11-19 2022-01-05 Institute Of Cancer Res Royal Cancer Hospital Prognostic and treatment response predictive method
CN115369089A (zh) * 2022-08-11 2022-11-22 中山大学孙逸仙纪念医院 两种er阳性her-2阴性乳腺癌cdk4/6抑制剂耐药株及其构建方法和用途
CN116327894A (zh) * 2023-04-10 2023-06-27 上海市第一妇婴保健院 一种治疗kras突变的卵巢癌的组合药物及其应用
WO2025202871A1 (en) * 2024-03-27 2025-10-02 Pfizer Inc. Methods for identifying biomarkers of treatment response and use thereof with a cdk4 inhibitor

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018518529A (ja) 2015-04-29 2018-07-12 ラジウス ファーマシューティカルズ，インコーポレイテッド 癌を治療するための方法
WO2018129419A1 (en) 2017-01-05 2018-07-12 Radius Pharmaceuticals, Inc. Polymorphic forms of rad1901-2hcl

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9421264B2 (en) * 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
SG11202013177WA (en) * 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018518529A (ja) 2015-04-29 2018-07-12 ラジウス ファーマシューティカルズ，インコーポレイテッド 癌を治療するための方法
WO2018129419A1 (en) 2017-01-05 2018-07-12 Radius Pharmaceuticals, Inc. Polymorphic forms of rad1901-2hcl

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PH12021551319A1 (en) 2022-05-16
AU2019395093A1 (en) 2021-06-24
UA130036C2 (uk) 2025-10-22
MA54388A (fr) 2021-10-13
AU2019395093B2 (en) 2025-01-23
MX2021006411A (es) 2021-07-21
JOP20210137A1 (ar) 2023-01-30
JP2022511498A (ja) 2022-01-31
CN119548484A (zh) 2025-03-04
EP3890834A1 (en) 2021-10-13
US20250319044A1 (en) 2025-10-16
CN113164779A (zh) 2021-07-23
EA202191283A1 (ru) 2021-10-13
IL283659A (en) 2021-07-29
KR20210100137A (ko) 2021-08-13
WO2020118213A1 (en) 2020-06-11
US20210330612A1 (en) 2021-10-28
CA3121930A1 (en) 2020-06-11
BR112021010110A2 (pt) 2021-08-24
SG11202105531XA (en) 2021-06-29

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