JP7485368B2 - 新規な融合タンパク質およびこれを含む癌の予防または治療用薬学的組成物 - Google Patents
新規な融合タンパク質およびこれを含む癌の予防または治療用薬学的組成物 Download PDFInfo
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
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| KR10-2018-0048343 | 2018-04-26 | ||
| KR20180048343 | 2018-04-26 | ||
| PCT/KR2019/005096 WO2019209078A1 (ko) | 2018-04-26 | 2019-04-26 | 신규한 융합 단백질 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
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| JP2021521817A JP2021521817A (ja) | 2021-08-30 |
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| EP (1) | EP3792276A4 (https=) |
| JP (1) | JP7485368B2 (https=) |
| KR (3) | KR102194644B1 (https=) |
| CN (1) | CN112041333B (https=) |
| WO (1) | WO2019209078A1 (https=) |
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| US20210347849A1 (en) * | 2018-07-24 | 2021-11-11 | Good T Cells, Inc. | Composition for Preventing or Treating Immune-Related Diseases |
| CN113811330A (zh) * | 2019-03-20 | 2021-12-17 | 古德T细胞有限公司 | 预防或治疗脑和神经系统疾病的组合物 |
| AU2020380072B2 (en) * | 2019-11-08 | 2025-11-27 | Good T Cells, Inc. | Epitope of regulatory T cell surface antigen, and antibody specifically binding thereto |
| CN111285936A (zh) * | 2020-03-11 | 2020-06-16 | 北京双赢科创生物科技有限公司 | 靶向肿瘤的酸性敏感纳米肽段及其应用 |
| KR20250036703A (ko) * | 2023-09-06 | 2025-03-14 | 주식회사 굳티셀 | 친화도 성숙이 이루어진 신규 항체 |
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| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US6086875A (en) | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| JP2008504008A (ja) * | 2003-12-31 | 2008-02-14 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 改良された薬物動態を有するＦｃ−エリスロポエチン融合タンパク質 |
| WO2007013671A2 (en) * | 2005-07-27 | 2007-02-01 | Oncotherapy Science, Inc. | Method of diagnosing esophageal cancer |
| US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| CN105131127B (zh) | 2007-05-30 | 2018-09-07 | 浦项工科大学校产学协力团 | 免疫球蛋白融合蛋白 |
| US8933197B2 (en) * | 2007-08-15 | 2015-01-13 | Amunix Operating Inc. | Compositions comprising modified biologically active polypeptides |
| CN101891823B (zh) * | 2010-06-11 | 2012-10-03 | 北京东方百泰生物科技有限公司 | 一种Exendin-4及其类似物融合蛋白 |
| KR101847523B1 (ko) | 2011-01-24 | 2018-05-28 | 연세대학교 산학협력단 | 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도 |
| RS61391B1 (sr) | 2012-06-08 | 2021-02-26 | Alkermes Pharma Ireland Ltd | Ligandi modifikovani primenom cirkularnog permutiranja kao agonisti i antagonisti |
| EP3456734B1 (en) | 2012-10-04 | 2022-01-05 | Research Development Foundation | Serine protease molecules and therapies |
| WO2015016616A1 (ko) * | 2013-07-30 | 2015-02-05 | 연세대학교 산학협력단 | 삭사틸린-Ｆｃ 융합 단백질 및 이의 용도 |
| US20210347849A1 (en) | 2018-07-24 | 2021-11-11 | Good T Cells, Inc. | Composition for Preventing or Treating Immune-Related Diseases |
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| EP3792276A4 (en) | 2022-02-16 |
| KR20230146491A (ko) | 2023-10-19 |
| US20210130422A1 (en) | 2021-05-06 |
| JP2021521817A (ja) | 2021-08-30 |
| US11820801B2 (en) | 2023-11-21 |
| KR102754984B1 (ko) | 2025-01-21 |
| CN112041333B (zh) | 2024-06-28 |
| CN112041333A (zh) | 2020-12-04 |
| KR20200144524A (ko) | 2020-12-29 |
| WO2019209078A1 (ko) | 2019-10-31 |
| KR102194644B1 (ko) | 2020-12-24 |
| KR20190124665A (ko) | 2019-11-05 |
| EP3792276A1 (en) | 2021-03-17 |
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