JP7478251B2 - イオンチャネルアンタゴニスト／遮断剤およびその用途 - Google Patents

イオンチャネルアンタゴニスト／遮断剤およびその用途 Download PDF

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JP7478251B2
JP7478251B2 JP2022561215A JP2022561215A JP7478251B2 JP 7478251 B2 JP7478251 B2 JP 7478251B2 JP 2022561215 A JP2022561215 A JP 2022561215A JP 2022561215 A JP2022561215 A JP 2022561215A JP 7478251 B2 JP7478251 B2 JP 7478251B2
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mmol
group
naphthalen
methyl
reaction mixture
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JP2023506096A5 (https=
JP2023506096A (ja
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チェン，イーハン
リアン，ダンダン
リュー，イ
マン サクヤ，スーバス
ヤン，ジンフア
リー，リー
シエ，ドゥアンヤン
シ，ダン
シオン，ケ
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Shanghai East Hospital
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Shanghai East Hospital
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    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
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    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
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    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
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    • C07C43/202—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a naphthalene
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    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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