JP7466905B2 - 二段階相同組換え修復によるスカーレスゲノム編集 - Google Patents

二段階相同組換え修復によるスカーレスゲノム編集 Download PDF

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JP7466905B2
JP7466905B2 JP2020502409A JP2020502409A JP7466905B2 JP 7466905 B2 JP7466905 B2 JP 7466905B2 JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020502409 A JP2020502409 A JP 2020502409A JP 7466905 B2 JP7466905 B2 JP 7466905B2
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cell
cells
cas9
sequence
donor polynucleotide
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和哉 池田
マシュー エイチ． ポルテウス
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Leland Stanford Junior University
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JP2020502409A 2017-07-18 2018-07-18 二段階相同組換え修復によるスカーレスゲノム編集 Active JP7466905B2 (ja)

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JP2024008447A JP7795216B2 (ja) 2017-07-18 2024-01-24 二段階相同組換え修復によるスカーレスゲノム編集
JP2025178375A JP2026012842A (ja) 2017-07-18 2025-10-23 二段階相同組換え修復によるスカーレスゲノム編集

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US201762533780P 2017-07-18 2017-07-18
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PCT/US2018/042702 WO2019018534A1 (en) 2017-07-18 2018-07-18 GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY

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WO2019018534A1 (en) 2017-07-18 2019-01-24 The Board Of Trustees Of Leland Stanford Junior University GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY
WO2020206134A1 (en) * 2019-04-04 2020-10-08 Regeneron Pharmaceuticals, Inc. Methods for scarless introduction of targeted modifications into targeting vectors
CN113151339B (zh) * 2020-01-23 2022-07-01 中国科学院大连化学物理研究所 一种基因突变表达盒及其应用
US20230147287A1 (en) * 2020-04-06 2023-05-11 LogoMix, Inc. Genome engineering method and genome engineering kit
US11214811B1 (en) 2020-07-31 2022-01-04 Inari Agriculture Technology, Inc. INIR6 transgenic maize
WO2022026395A2 (en) * 2020-07-31 2022-02-03 Inari Agriculture Technology, Inc. Excisable plant transgenic loci with signature protospacer adjacent motifs or signature guide rna recognition sites
US20240011043A1 (en) 2020-07-31 2024-01-11 Inari Agriculture Technology, Inc. Generation of plants with improved transgenic loci by genome editing
BR112023001774A2 (pt) * 2020-07-31 2023-03-07 Inari Agriculture Tech Inc Genoma de planta transgênica editado, célula de planta transgênica, planta transgênica, parte de planta transgênica, método para obter uma população avolumada de sementes endogâmicas para produção de sementes comerciais, método de obtenção de semente de cultura híbrida, molécula de dna, produto de planta transgênica processado, amostra biológica, marcador de ácido nucleico adaptado para detecção de dna genômico ou seus fragmentos, método de detecção do genoma de planta transgênica editado, método de obtenção de um genoma de planta transgênica editado compreendendo um lócus transgênico modificado, método de excisão de um lócus transgênico modificado ou sua porção a partir de um genoma de planta transgênica editado, método de obtenção de uma linha de reprodução de plantas, método para obter germoplasma de planta transgênica endogâmico contendo diferentes traços transgênicos
US20240358008A1 (en) * 2021-08-31 2024-10-31 New York University COMPOSITIONS AND METHODS FOR SWITCHING ANTIBIOTIC RESISTANCE MARKERS PROGRESSIVELY FOR INTEGRATION (mSwAP-In)
TW202332770A (zh) * 2021-09-24 2023-08-16 大陸商上海伊米諾康生物科技有限公司 大尺寸染色體轉移方法及使用該方法產生的經修飾的染色體和生物體
WO2024020596A1 (en) * 2022-07-22 2024-01-25 Villanova University Methods and compositions comprising fusion proteins for the identification of immunotherapy cells
WO2024263652A1 (en) * 2023-06-19 2024-12-26 The Regents Of The University Of California Compositions for and methods of tagging endogenously expressed proteins
IT202300019377A1 (it) * 2023-09-20 2025-03-20 Univ Degli Studi Di Pavia Linee di cellule staminali contenenti proteine endogene marcate con espressione differenziale, metodi di produzione e loro utilizzo per l’identificazione del ciclo cellulare
WO2025126797A1 (ja) * 2023-12-13 2025-06-19 国立大学法人 東京大学 高効率な長鎖核酸配列の部位特異的ノックイン法
WO2025182957A1 (ja) * 2024-02-26 2025-09-04 株式会社ニチレイフーズ 改変ｄｎａを含む細胞の作製方法、該細胞を含む生物体の作製方法、及び遺伝子産物の生産方法

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WO2019018534A1 (en) 2017-07-18 2019-01-24 The Board Of Trustees Of Leland Stanford Junior University GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY

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CN108085328A (zh) 2016-11-21 2018-05-29 中国科学院上海生命科学研究院 一种dna序列编辑的方法

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JP2026012842A (ja) 2026-01-27
JP2024045294A (ja) 2024-04-02
US12442016B2 (en) 2025-10-14
US11692202B2 (en) 2023-07-04
US20200208172A1 (en) 2020-07-02
WO2019018534A1 (en) 2019-01-24
WO2019018534A8 (en) 2020-02-20
US20260078401A1 (en) 2026-03-19
US20230348932A1 (en) 2023-11-02
JP2020532291A (ja) 2020-11-12

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