JP2020532291A5 - - Google Patents
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- JP2020532291A5 JP2020532291A5 JP2020502409A JP2020502409A JP2020532291A5 JP 2020532291 A5 JP2020532291 A5 JP 2020532291A5 JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020532291 A5 JP2020532291 A5 JP 2020532291A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- homology arm
- donor polynucleotide
- genomic dna
- selectable marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024008447A JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762533780P | 2017-07-18 | 2017-07-18 | |
| US62/533,780 | 2017-07-18 | ||
| PCT/US2018/042702 WO2019018534A1 (en) | 2017-07-18 | 2018-07-18 | GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008447A Division JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532291A JP2020532291A (ja) | 2020-11-12 |
| JP2020532291A5 true JP2020532291A5 (https=) | 2021-08-26 |
| JP7466905B2 JP7466905B2 (ja) | 2024-04-15 |
Family
ID=65016692
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502409A Active JP7466905B2 (ja) | 2017-07-18 | 2018-07-18 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2024008447A Active JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A Pending JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008447A Active JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A Pending JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US11692202B2 (https=) |
| JP (3) | JP7466905B2 (https=) |
| WO (1) | WO2019018534A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7466905B2 (ja) | 2017-07-18 | 2024-04-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 二段階相同組換え修復によるスカーレスゲノム編集 |
| RU2771374C1 (ru) * | 2019-04-04 | 2022-05-04 | Редженерон Фармасьютикалс, Инк. | Способы для бесшовного внесения целевых модификаций в направленные векторы |
| CN113151339B (zh) * | 2020-01-23 | 2022-07-01 | 中国科学院大连化学物理研究所 | 一种基因突变表达盒及其应用 |
| CN115552002A (zh) * | 2020-04-06 | 2022-12-30 | 株式会社标志融合 | 基因组改造方法及基因组改造试剂盒 |
| US11214811B1 (en) | 2020-07-31 | 2022-01-04 | Inari Agriculture Technology, Inc. | INIR6 transgenic maize |
| CN116390644A (zh) * | 2020-07-31 | 2023-07-04 | 伊纳瑞农业技术有限公司 | 通过基因组编辑产生具有改进的转基因基因座的植物 |
| US20240011043A1 (en) | 2020-07-31 | 2024-01-11 | Inari Agriculture Technology, Inc. | Generation of plants with improved transgenic loci by genome editing |
| EP4172342A4 (en) * | 2020-07-31 | 2024-10-02 | Inari Agriculture Technology, Inc. | REMOVABLE TRANSGENIC PLANT LOCI WITH RELATED RNA GUIDE RECOGNITION SITES |
| US20240358008A1 (en) * | 2021-08-31 | 2024-10-31 | New York University | COMPOSITIONS AND METHODS FOR SWITCHING ANTIBIOTIC RESISTANCE MARKERS PROGRESSIVELY FOR INTEGRATION (mSwAP-In) |
| US20250027116A1 (en) * | 2021-09-24 | 2025-01-23 | Immunocan Biotech Co. Ltd. | Methods for large-size chromosomal transfer and modified chromosomes and organisims using same |
| WO2024020596A1 (en) * | 2022-07-22 | 2024-01-25 | Villanova University | Methods and compositions comprising fusion proteins for the identification of immunotherapy cells |
| WO2024263652A1 (en) * | 2023-06-19 | 2024-12-26 | The Regents Of The University Of California | Compositions for and methods of tagging endogenously expressed proteins |
| IT202300019377A1 (it) * | 2023-09-20 | 2025-03-20 | Univ Degli Studi Di Pavia | Linee di cellule staminali contenenti proteine endogene marcate con espressione differenziale, metodi di produzione e loro utilizzo per l’identificazione del ciclo cellulare |
| WO2025126797A1 (ja) * | 2023-12-13 | 2025-06-19 | 国立大学法人 東京大学 | 高効率な長鎖核酸配列の部位特異的ノックイン法 |
| WO2025182957A1 (ja) * | 2024-02-26 | 2025-09-04 | 株式会社ニチレイフーズ | 改変ｄｎａを含む細胞の作製方法、該細胞を含む生物体の作製方法、及び遺伝子産物の生産方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014143381A1 (en) * | 2013-03-09 | 2014-09-18 | Agilent Technologies, Inc. | Methods of in vivo engineering of large sequences using multiple crispr/cas selections of recombineering events |
| KR102170502B1 (ko) * | 2013-12-11 | 2020-10-28 | 리제너론 파마슈티칼스 인코포레이티드 | 게놈의 표적화된 변형을 위한 방법 및 조성물 |
| CN108085328B (zh) * | 2016-11-21 | 2021-06-22 | 中国科学院分子植物科学卓越创新中心 | 一种dna序列编辑的方法 |
| JP7466905B2 (ja) | 2017-07-18 | 2024-04-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 二段階相同組換え修復によるスカーレスゲノム編集 |
-
2018
- 2018-07-18 JP JP2020502409A patent/JP7466905B2/ja active Active
- 2018-07-18 WO PCT/US2018/042702 patent/WO2019018534A1/en not_active Ceased
-
2020
- 2020-01-10 US US16/740,234 patent/US11692202B2/en active Active
-
2023
- 2023-05-18 US US18/320,132 patent/US12442016B2/en active Active
-
2024
- 2024-01-24 JP JP2024008447A patent/JP7795216B2/ja active Active
-
2025
- 2025-09-22 US US19/336,224 patent/US20260078401A1/en active Pending
- 2025-10-23 JP JP2025178375A patent/JP2026012842A/ja active Pending
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