JP2020532291A5 - - Google Patents
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- Publication number
- JP2020532291A5 JP2020532291A5 JP2020502409A JP2020502409A JP2020532291A5 JP 2020532291 A5 JP2020532291 A5 JP 2020532291A5 JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020532291 A5 JP2020532291 A5 JP 2020532291A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- homology arm
- donor polynucleotide
- genomic dna
- selectable marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024008447A JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762533780P | 2017-07-18 | 2017-07-18 | |
| US62/533,780 | 2017-07-18 | ||
| PCT/US2018/042702 WO2019018534A1 (en) | 2017-07-18 | 2018-07-18 | GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008447A Division JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532291A JP2020532291A (ja) | 2020-11-12 |
| JP2020532291A5 true JP2020532291A5 (https=) | 2021-08-26 |
| JP7466905B2 JP7466905B2 (ja) | 2024-04-15 |
Family
ID=65016692
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502409A Active JP7466905B2 (ja) | 2017-07-18 | 2018-07-18 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2024008447A Active JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A Pending JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008447A Active JP7795216B2 (ja) | 2017-07-18 | 2024-01-24 | 二段階相同組換え修復によるスカーレスゲノム編集 |
| JP2025178375A Pending JP2026012842A (ja) | 2017-07-18 | 2025-10-23 | 二段階相同組換え修復によるスカーレスゲノム編集 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US11692202B2 (https=) |
| JP (3) | JP7466905B2 (https=) |
| WO (1) | WO2019018534A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019018534A1 (en) | 2017-07-18 | 2019-01-24 | The Board Of Trustees Of Leland Stanford Junior University | GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY |
| WO2020206134A1 (en) * | 2019-04-04 | 2020-10-08 | Regeneron Pharmaceuticals, Inc. | Methods for scarless introduction of targeted modifications into targeting vectors |
| CN113151339B (zh) * | 2020-01-23 | 2022-07-01 | 中国科学院大连化学物理研究所 | 一种基因突变表达盒及其应用 |
| US20230147287A1 (en) * | 2020-04-06 | 2023-05-11 | LogoMix, Inc. | Genome engineering method and genome engineering kit |
| US11214811B1 (en) | 2020-07-31 | 2022-01-04 | Inari Agriculture Technology, Inc. | INIR6 transgenic maize |
| WO2022026395A2 (en) * | 2020-07-31 | 2022-02-03 | Inari Agriculture Technology, Inc. | Excisable plant transgenic loci with signature protospacer adjacent motifs or signature guide rna recognition sites |
| US20240011043A1 (en) | 2020-07-31 | 2024-01-11 | Inari Agriculture Technology, Inc. | Generation of plants with improved transgenic loci by genome editing |
| BR112023001774A2 (pt) * | 2020-07-31 | 2023-03-07 | Inari Agriculture Tech Inc | Genoma de planta transgênica editado, célula de planta transgênica, planta transgênica, parte de planta transgênica, método para obter uma população avolumada de sementes endogâmicas para produção de sementes comerciais, método de obtenção de semente de cultura híbrida, molécula de dna, produto de planta transgênica processado, amostra biológica, marcador de ácido nucleico adaptado para detecção de dna genômico ou seus fragmentos, método de detecção do genoma de planta transgênica editado, método de obtenção de um genoma de planta transgênica editado compreendendo um lócus transgênico modificado, método de excisão de um lócus transgênico modificado ou sua porção a partir de um genoma de planta transgênica editado, método de obtenção de uma linha de reprodução de plantas, método para obter germoplasma de planta transgênica endogâmico contendo diferentes traços transgênicos |
| US20240358008A1 (en) * | 2021-08-31 | 2024-10-31 | New York University | COMPOSITIONS AND METHODS FOR SWITCHING ANTIBIOTIC RESISTANCE MARKERS PROGRESSIVELY FOR INTEGRATION (mSwAP-In) |
| TW202332770A (zh) * | 2021-09-24 | 2023-08-16 | 大陸商上海伊米諾康生物科技有限公司 | 大尺寸染色體轉移方法及使用該方法產生的經修飾的染色體和生物體 |
| WO2024020596A1 (en) * | 2022-07-22 | 2024-01-25 | Villanova University | Methods and compositions comprising fusion proteins for the identification of immunotherapy cells |
| WO2024263652A1 (en) * | 2023-06-19 | 2024-12-26 | The Regents Of The University Of California | Compositions for and methods of tagging endogenously expressed proteins |
| IT202300019377A1 (it) * | 2023-09-20 | 2025-03-20 | Univ Degli Studi Di Pavia | Linee di cellule staminali contenenti proteine endogene marcate con espressione differenziale, metodi di produzione e loro utilizzo per l’identificazione del ciclo cellulare |
| WO2025126797A1 (ja) * | 2023-12-13 | 2025-06-19 | 国立大学法人 東京大学 | 高効率な長鎖核酸配列の部位特異的ノックイン法 |
| WO2025182957A1 (ja) * | 2024-02-26 | 2025-09-04 | 株式会社ニチレイフーズ | 改変ｄｎａを含む細胞の作製方法、該細胞を含む生物体の作製方法、及び遺伝子産物の生産方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014143381A1 (en) * | 2013-03-09 | 2014-09-18 | Agilent Technologies, Inc. | Methods of in vivo engineering of large sequences using multiple crispr/cas selections of recombineering events |
| US9546384B2 (en) * | 2013-12-11 | 2017-01-17 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for the targeted modification of a mouse genome |
| CN108085328B (zh) | 2016-11-21 | 2021-06-22 | 中国科学院分子植物科学卓越创新中心 | 一种dna序列编辑的方法 |
| WO2019018534A1 (en) | 2017-07-18 | 2019-01-24 | The Board Of Trustees Of Leland Stanford Junior University | GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY |
-
2018
- 2018-07-18 WO PCT/US2018/042702 patent/WO2019018534A1/en not_active Ceased
- 2018-07-18 JP JP2020502409A patent/JP7466905B2/ja active Active
-
2020
- 2020-01-10 US US16/740,234 patent/US11692202B2/en active Active
-
2023
- 2023-05-18 US US18/320,132 patent/US12442016B2/en active Active
-
2024
- 2024-01-24 JP JP2024008447A patent/JP7795216B2/ja active Active
-
2025
- 2025-09-22 US US19/336,224 patent/US20260078401A1/en active Pending
- 2025-10-23 JP JP2025178375A patent/JP2026012842A/ja active Pending
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