JP7419070B2 - 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 - Google Patents
免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 Download PDFInfo
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- JP7419070B2 JP7419070B2 JP2019557434A JP2019557434A JP7419070B2 JP 7419070 B2 JP7419070 B2 JP 7419070B2 JP 2019557434 A JP2019557434 A JP 2019557434A JP 2019557434 A JP2019557434 A JP 2019557434A JP 7419070 B2 JP7419070 B2 JP 7419070B2
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- G—PHYSICS
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
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- G21F5/00—Transportable or portable shielded containers
- G21F5/06—Details of, or accessories to, the containers
- G21F5/14—Devices for handling containers or shipping-casks, e.g. transporting devices loading and unloading, filling of containers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
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- Zoology (AREA)
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- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024001630A JP2024041874A (ja) | 2017-04-20 | 2024-01-10 | 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762487823P | 2017-04-20 | 2017-04-20 | |
| US62/487,823 | 2017-04-20 | ||
| PCT/US2018/028505 WO2018195386A1 (en) | 2017-04-20 | 2018-04-20 | Methods and compositions for treating cancer with ecm-affinity peptides linked to immunotherapeutic antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001630A Division JP2024041874A (ja) | 2017-04-20 | 2024-01-10 | 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020517658A JP2020517658A (ja) | 2020-06-18 |
| JP2020517658A5 JP2020517658A5 (https=) | 2021-05-27 |
| JP7419070B2 true JP7419070B2 (ja) | 2024-01-22 |
Family
ID=63856403
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019557434A Active JP7419070B2 (ja) | 2017-04-20 | 2018-04-20 | 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 |
| JP2024001630A Pending JP2024041874A (ja) | 2017-04-20 | 2024-01-10 | 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001630A Pending JP2024041874A (ja) | 2017-04-20 | 2024-01-10 | 免疫療法用抗体と連結させたecm親和性ペプチドを用いてがんを処置するための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11574747B2 (https=) |
| EP (1) | EP3612209A4 (https=) |
| JP (2) | JP7419070B2 (https=) |
| CN (1) | CN111132693A (https=) |
| AU (2) | AU2018256453B2 (https=) |
| MX (1) | MX2019012579A (https=) |
| WO (1) | WO2018195386A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2889182A1 (en) * | 2012-10-26 | 2014-05-01 | The University Of Chicago | Synergistic combination of immunologic inhibitors for the treatment of cancer |
| CN108623686A (zh) | 2017-03-25 | 2018-10-09 | 信达生物制药(苏州)有限公司 | 抗ox40抗体及其用途 |
| MX2019012579A (es) * | 2017-04-20 | 2020-07-28 | Univ Chicago | Métodos y composiciones para tratar el cáncer con péptidos de afinidad de mec ligados a anticuerpos inmunoterapéuticos. |
| US11732029B2 (en) | 2017-11-13 | 2023-08-22 | The University Chicago | Methods and compositions for the treatment of wounds |
| AU2019232729B2 (en) * | 2018-03-05 | 2024-08-08 | The University Of Chicago | Methods and compositions for treating cancer with ECM-affinity peptides linked to cytokines |
| CN112638403A (zh) | 2018-07-03 | 2021-04-09 | 康泰伦特药物解决方案有限责任公司 | 包括饰胶蛋白聚糖的多功能蛋白质分子及其用途 |
| CN113710229B (zh) * | 2019-02-25 | 2026-01-06 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| BR112021024402A2 (pt) * | 2019-06-03 | 2022-02-15 | Univ Chicago | Métodos e composições para tratamento de câncer com adjuvantes direcionados ao câncer |
| JP7772700B2 (ja) * | 2019-12-19 | 2025-11-18 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 神経膠芽腫を処置するための方法 |
| CN115065734A (zh) * | 2021-02-27 | 2022-09-16 | 华为技术有限公司 | 一种数据处理方法、装置及芯片 |
| WO2025203029A1 (en) * | 2024-03-28 | 2025-10-02 | Hadasit Medical Research Services And Development Ltd. | Tricer - a tri-specific cell engager and retainer |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003532681A (ja) | 2000-05-05 | 2003-11-05 | ジーティーシー バイオセラピューティックス インコーポレイテッド | 遺伝子導入により産生されたデコリン |
| JP2015527307A (ja) | 2012-07-03 | 2015-09-17 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) | 胎盤成長因子からの配列を含有するコンジュゲートならびに生体材料および医薬の成分としてのその使用 |
| WO2016054107A1 (en) | 2014-09-29 | 2016-04-07 | Counterpoint Biomedica Llc | Targeting of pharmaceutical agents to pathologic areas using bifunctional fusion polymers |
| WO2016054555A2 (en) | 2014-10-03 | 2016-04-07 | Novartis Ag | Combination therapies |
| WO2017009842A2 (en) | 2015-07-16 | 2017-01-19 | Biokine Therapeutics Ltd. | Compositions and methods for treating cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5654270A (en) * | 1988-06-28 | 1997-08-05 | La Jolla Cancer Research Foundation | Use of fibromodulin to prevent or reduce dermal scarring |
| US6482411B1 (en) | 1999-08-27 | 2002-11-19 | Board Of Regents, The University Of Texas System | Methods of reducing bone loss with CD40 ligand |
| US20080160024A1 (en) * | 2006-12-07 | 2008-07-03 | Board Of Trustees Of The University Of Arkansas | Inhibition of cancer metastasis |
| AT504685B1 (de) * | 2006-12-20 | 2009-01-15 | Protaffin Biotechnologie Ag | Fusionsproteine |
| KR101808751B1 (ko) * | 2009-11-13 | 2017-12-13 | 그리폴스 테라퓨틱스 인코포레이티드 | 폰 빌레브란트 인자(vWF)-함유 제제, 및 그와 관련된 방법, 키트 및 용도 |
| MX2019012579A (es) * | 2017-04-20 | 2020-07-28 | Univ Chicago | Métodos y composiciones para tratar el cáncer con péptidos de afinidad de mec ligados a anticuerpos inmunoterapéuticos. |
-
2018
- 2018-04-20 MX MX2019012579A patent/MX2019012579A/es unknown
- 2018-04-20 EP EP18787963.0A patent/EP3612209A4/en active Pending
- 2018-04-20 US US16/606,539 patent/US11574747B2/en active Active
- 2018-04-20 CN CN201880041832.4A patent/CN111132693A/zh active Pending
- 2018-04-20 JP JP2019557434A patent/JP7419070B2/ja active Active
- 2018-04-20 WO PCT/US2018/028505 patent/WO2018195386A1/en not_active Ceased
- 2018-04-20 AU AU2018256453A patent/AU2018256453B2/en active Active
-
2023
- 2023-02-03 US US18/164,164 patent/US20230377764A1/en active Pending
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2024
- 2024-01-10 JP JP2024001630A patent/JP2024041874A/ja active Pending
- 2024-05-02 AU AU2024202918A patent/AU2024202918A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003532681A (ja) | 2000-05-05 | 2003-11-05 | ジーティーシー バイオセラピューティックス インコーポレイテッド | 遺伝子導入により産生されたデコリン |
| JP2015527307A (ja) | 2012-07-03 | 2015-09-17 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) | 胎盤成長因子からの配列を含有するコンジュゲートならびに生体材料および医薬の成分としてのその使用 |
| WO2016054107A1 (en) | 2014-09-29 | 2016-04-07 | Counterpoint Biomedica Llc | Targeting of pharmaceutical agents to pathologic areas using bifunctional fusion polymers |
| WO2016054555A2 (en) | 2014-10-03 | 2016-04-07 | Novartis Ag | Combination therapies |
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| US11574747B2 (en) | 2023-02-07 |
| WO2018195386A1 (en) | 2018-10-25 |
| EP3612209A4 (en) | 2021-03-24 |
| CN111132693A (zh) | 2020-05-08 |
| JP2024041874A (ja) | 2024-03-27 |
| JP2020517658A (ja) | 2020-06-18 |
| AU2018256453B2 (en) | 2024-02-08 |
| MX2019012579A (es) | 2020-07-28 |
| EP3612209A1 (en) | 2020-02-26 |
| US20200123228A1 (en) | 2020-04-23 |
| AU2018256453A1 (en) | 2019-12-05 |
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| US20230377764A1 (en) | 2023-11-23 |
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