JP7418024B2 - トンネル電流を使用したマイクロrna解析 - Google Patents

トンネル電流を使用したマイクロrna解析 Download PDF

Info

Publication number
JP7418024B2
JP7418024B2 JP2021516247A JP2021516247A JP7418024B2 JP 7418024 B2 JP7418024 B2 JP 7418024B2 JP 2021516247 A JP2021516247 A JP 2021516247A JP 2021516247 A JP2021516247 A JP 2021516247A JP 7418024 B2 JP7418024 B2 JP 7418024B2
Authority
JP
Japan
Prior art keywords
microrna
modification
state
tunneling current
base sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2021516247A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2020218489A5 (https=
JPWO2020218489A1 (https=
Inventor
正輝 谷口
秀始 石井
敬人 大城
雅允 今野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Osaka NUC
Original Assignee
Osaka University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University NUC filed Critical Osaka University NUC
Publication of JPWO2020218489A1 publication Critical patent/JPWO2020218489A1/ja
Publication of JPWO2020218489A5 publication Critical patent/JPWO2020218489A5/ja
Application granted granted Critical
Publication of JP7418024B2 publication Critical patent/JP7418024B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
JP2021516247A 2019-04-26 2020-04-24 トンネル電流を使用したマイクロrna解析 Active JP7418024B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019085805 2019-04-26
JP2019085805 2019-04-26
PCT/JP2020/017654 WO2020218489A1 (ja) 2019-04-26 2020-04-24 トンネル電流を使用したマイクロrna解析

Publications (3)

Publication Number Publication Date
JPWO2020218489A1 JPWO2020218489A1 (https=) 2020-10-29
JPWO2020218489A5 JPWO2020218489A5 (https=) 2022-11-25
JP7418024B2 true JP7418024B2 (ja) 2024-01-19

Family

ID=72942125

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021516247A Active JP7418024B2 (ja) 2019-04-26 2020-04-24 トンネル電流を使用したマイクロrna解析

Country Status (3)

Country Link
US (1) US20230194472A1 (https=)
JP (1) JP7418024B2 (https=)
WO (1) WO2020218489A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12391986B2 (en) * 2021-09-30 2025-08-19 Microsoft Technology Licensing, Llc Anti-counterfeit tags using base ratios of polynucleotides
US12530651B2 (en) 2021-10-26 2026-01-20 Microsoft Technology Licensing, Llc Synthetic molecular tags for supply chain tracking
JPWO2024247764A1 (https=) * 2023-05-30 2024-12-05
US20250022560A1 (en) * 2023-07-10 2025-01-16 Ayble Health, Inc. Individualized management system for treating disease, including gi diseases, and methods of use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012231801A (ja) 2006-03-02 2012-11-29 Ohio State Univ 膵臓癌に関連するマイクロrna発現プロファイル
WO2013147208A1 (ja) 2012-03-29 2013-10-03 国立大学法人大阪大学 ポリヌクレオチドの塩基配列を決定する方法、および、ポリヌクレオチドの塩基配列を決定する装置
JP2017227657A (ja) 2011-07-27 2017-12-28 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 生体分子を特徴付けるためのナノ細孔センサー

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101354480B1 (ko) * 2012-05-14 2014-01-27 한국과학기술연구원 나노채널과 결합된 나노포어를 이용한 입자 검출 장치 및 방법
DE102013215666B4 (de) * 2013-08-08 2024-06-13 Siemens Healthineers Ag Verfahren zum Sequenzieren von Biopolymeren
WO2017207613A1 (en) * 2016-05-31 2017-12-07 F. Hoffmann-La Roche Ag Methods and systems for nucleic acid sequencing by tunneling recognition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012231801A (ja) 2006-03-02 2012-11-29 Ohio State Univ 膵臓癌に関連するマイクロrna発現プロファイル
JP2017227657A (ja) 2011-07-27 2017-12-28 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 生体分子を特徴付けるためのナノ細孔センサー
WO2013147208A1 (ja) 2012-03-29 2013-10-03 国立大学法人大阪大学 ポリヌクレオチドの塩基配列を決定する方法、および、ポリヌクレオチドの塩基配列を決定する装置

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
谷口正輝 ほか,1分子DNAシークエンサーが生み出すビッグデータ,第30回人工知能学会全国大会論文集,1B4-OS-01a-2,2016年,PP.1-2
谷口正輝,1分子シークエンサーの現状と可能性,化学と生物,Vol.54/No.6,2016年,PP.396-402

Also Published As

Publication number Publication date
WO2020218489A1 (ja) 2020-10-29
JPWO2020218489A1 (https=) 2020-10-29
US20230194472A1 (en) 2023-06-22

Similar Documents

Publication Publication Date Title
JP7125782B2 (ja) Rna修飾を利用した分析・診断法
JP7418024B2 (ja) トンネル電流を使用したマイクロrna解析
Drexler et al. A prognostic neural epigenetic signature in high-grade glioma
Díez-Planelles et al. Circulating microRNAs in Huntington’s disease: Emerging mediators in metabolic impairment
Chaillou Ribosome specialization and its potential role in the control of protein translation and skeletal muscle size
Wang et al. Analysis of serum microRNA profile by solexa sequencing in women with endometriosis
US10407726B2 (en) miRNA biomarkers for radiation biodosimetry
US20030180710A1 (en) Method of enhancing the efficiency of a pharmaceutical business
Luo et al. Plasma exosomal miR-450b-5p as a possible biomarker and therapeutic target for transient ischaemic attacks in rats
US20250270645A1 (en) Algorithm and an in vitro method based on rna editing to select particular effect induced by active compounds
Zhang et al. High glucose causes distinct expression patterns of primary human skin cells by RNA sequencing
MacDonald et al. Laser capture microdissection–targeted mass spectrometry: a method for multiplexed protein quantification within individual layers of the cerebral cortex
Zhang et al. Dysregulation of mTOR signalling is a converging mechanism in lissencephaly
Zhao et al. Sequencing-free analysis of multiple methylations on gene-specific mRNAs
Zhong et al. Single‐cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury
Hao et al. Identification and validation of a novel mitochondrion-related gene signature for diagnosis and immune infiltration in sepsis
Beck et al. Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor–ligand interactions
CN109642256A (zh) 作为用于情绪障碍测试的生物标志物的rna编辑
KR101529633B1 (ko) 은 나노클러스터 형성을 이용한 테오필린의 검출방법
WO2024245463A1 (zh) 基于谷氨酰胺代谢模式的癌症风险评估方法及其应用
AU2014296212A1 (en) Methods and molecular pharmacodynamic biomarkers for multiple signaling pathways in response to carboxyamidotriazole orotate
Yu et al. Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration
JP2017029130A (ja) ヘキサナール曝露特異的メチル化マーカー遺伝子およびそれを用いた確認方法
US20240158860A1 (en) CIRCULATING miRNA MARKERS FOR DETECTION OF RADIATION EXPOSURE
JP2018537668A (ja) 組織試料での薬物結合分析法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221115

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20221115

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20230728

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20230822

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230905

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231102

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20231219

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20231226

R150 Certificate of patent or registration of utility model

Ref document number: 7418024

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150