JP7404331B2 - 膜結合型IL-10をコードする核酸分子及びそれを発現する遺伝子的にリプログラミングされたTreg - Google Patents

膜結合型IL-10をコードする核酸分子及びそれを発現する遺伝子的にリプログラミングされたTreg Download PDF

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JP7404331B2
JP7404331B2 JP2021500374A JP2021500374A JP7404331B2 JP 7404331 B2 JP7404331 B2 JP 7404331B2 JP 2021500374 A JP2021500374 A JP 2021500374A JP 2021500374 A JP2021500374 A JP 2021500374A JP 7404331 B2 JP7404331 B2 JP 7404331B2
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グロス、ギデオン
ウェインスタイン-マロム、ハダス
クローナー、アミット
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ガビッシュ-ガリラヤ バイオ アプリケーションズ リミテッド
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JP2021500374A 2018-03-23 2019-03-22 膜結合型IL-10をコードする核酸分子及びそれを発現する遺伝子的にリプログラミングされたTreg Active JP7404331B2 (ja)

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US201862647084P 2018-03-23 2018-03-23
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PCT/IL2019/050324 WO2019180724A1 (en) 2018-03-23 2019-03-22 Genetically reprogrammed tregs expressing membrane-bound il-10

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US20220186232A1 (en) * 2019-03-26 2022-06-16 Gavish-Galilee Bio Applications Ltd. Genetically reprogrammed tregs expressing cars
EP4536689A1 (en) * 2022-06-10 2025-04-16 Medizinische Hochschule Hannover Fusion protein for maintenance of regulatory t-cells
EP4289859A1 (en) * 2022-06-10 2023-12-13 Medizinische Hochschule Hannover Fusion protein for maintenance of regulatory t-cells
EP4565702A1 (en) * 2022-08-03 2025-06-11 Migal Galilee Research Institute Ltd. Chimeric membrane-bound cytokines incorporating costimulatory elements for enhancing anti-inflammatory function
WO2025148750A1 (zh) * 2024-01-08 2025-07-17 上药生物治疗(香港)有限公司 膜表达il-10及其用途
CN119331826B (zh) * 2024-12-18 2025-08-05 智在汉青生物科技(浙江)有限公司 用于增强细胞免疫疗法的表达非分泌型il-10的免疫细胞、制备方法及用途

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IL277541A (en) 2020-11-30
JP2024019533A (ja) 2024-02-09
WO2019180724A1 (en) 2019-09-26
US20210040169A1 (en) 2021-02-11
US20210347843A9 (en) 2021-11-11
JP2021519107A (ja) 2021-08-10
EP3768699B1 (en) 2025-11-12
AU2019240370B2 (en) 2024-03-07
SG11202010454PA (en) 2020-11-27
KR20210005602A (ko) 2021-01-14
AU2019240370A1 (en) 2020-11-19
CA3094927A1 (en) 2019-09-26
CN112088164A (zh) 2020-12-15
KR102943105B1 (ko) 2026-03-24

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