JP7402826B2 - がん悪液質において用いる化合物 - Google Patents
がん悪液質において用いる化合物 Download PDFInfo
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- JP7402826B2 JP7402826B2 JP2020567530A JP2020567530A JP7402826B2 JP 7402826 B2 JP7402826 B2 JP 7402826B2 JP 2020567530 A JP2020567530 A JP 2020567530A JP 2020567530 A JP2020567530 A JP 2020567530A JP 7402826 B2 JP7402826 B2 JP 7402826B2
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- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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Applications Claiming Priority (3)
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| GB1809113.2A GB2575623B (en) | 2018-06-04 | 2018-06-04 | 3-hydroxybutyrate esters for treating cancer cachexia |
| GB1809113.2 | 2018-06-04 | ||
| PCT/GB2019/051532 WO2019234402A1 (en) | 2018-06-04 | 2019-06-03 | Compounds for use in cancer cachexia |
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| JP2021525775A JP2021525775A (ja) | 2021-09-27 |
| JPWO2019234402A5 JPWO2019234402A5 (https=) | 2022-06-01 |
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| US12396974B2 (en) | 2020-03-27 | 2025-08-26 | KetoneAid | Ketone ester as a therapeutic treatment of Covid-19 and related viral infections |
| CN118591523A (zh) * | 2021-11-12 | 2024-09-03 | 阿萨达股份公司 | 多元醇衍生的化合物 |
| KR20250145172A (ko) | 2024-03-28 | 2025-10-13 | 한림대학교 산학협력단 | 암 악액질의 예방 또는 치료를 위한 약학 조성물 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012500264A (ja) | 2008-08-21 | 2012-01-05 | アイシス イノヴェイション リミテッド | ヒドロキシ酪酸エステル及びその医学的使用 |
| JP2013520454A (ja) | 2010-02-22 | 2013-06-06 | ティーデルタエス リミテッド | 栄養組成物 |
| JP2015514104A (ja) | 2012-04-05 | 2015-05-18 | ティーデルタエス リミテッド | 筋パワー出力を維持又は改善するためのケトン体及びケトン体エステル |
| JP2016512207A (ja) | 2013-03-12 | 2016-04-25 | ティーデルタエス リミテッド | 皮膚の保護に使用するための化合物 |
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|---|---|---|---|---|
| EP1648952B1 (en) * | 2003-06-03 | 2018-03-07 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives |
| EP3104396B1 (en) | 2003-06-13 | 2018-03-21 | Nikon Corporation | Exposure method, substrate stage, exposure apparatus, and device manufacturing method |
| US8642654B2 (en) * | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
| JP5269128B2 (ja) | 2010-03-12 | 2013-08-21 | エーエスエムエル ネザーランズ ビー.ブイ. | リソグラフィ装置および方法 |
| WO2014085652A1 (en) | 2012-11-28 | 2014-06-05 | University Of South Florida | Targeting cancer with metabolic therapy and hyperbaric oxygen |
| GB2515603B (en) | 2013-03-14 | 2015-10-14 | Isis Innovation | Process for producing (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate |
| GB201314127D0 (en) * | 2013-08-07 | 2013-09-18 | Tdeltas Ltd | Ketone body and ketone body ester for reducing muscle breakdown |
| WO2018114309A1 (en) * | 2016-12-23 | 2018-06-28 | Katholieke Universiteit Leuven | 3-hydroxybutyrate alone or in combination for use in the treatment of critical care treatment |
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2018
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2019
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012500264A (ja) | 2008-08-21 | 2012-01-05 | アイシス イノヴェイション リミテッド | ヒドロキシ酪酸エステル及びその医学的使用 |
| JP2013520454A (ja) | 2010-02-22 | 2013-06-06 | ティーデルタエス リミテッド | 栄養組成物 |
| JP2015514104A (ja) | 2012-04-05 | 2015-05-18 | ティーデルタエス リミテッド | 筋パワー出力を維持又は改善するためのケトン体及びケトン体エステル |
| JP2016512207A (ja) | 2013-03-12 | 2016-04-25 | ティーデルタエス リミテッド | 皮膚の保護に使用するための化合物 |
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| K. Clarke, et al.,Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects,Regul. Toxicol. Pharmacol.,2012年,Vol. 63, No. 3,401-408 |
| K. Clarke, et al.,Oral 28-day and developmental toxicity studies of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate,Regul. Toxicol. Pharmacol.,2012年,Vol. 63, No. 2,196-208 |
| K. Nakamura, H. Tonouchi, A. Sasayama and K. Ashida,A Ketogenic Formula Prevents Tumor Progression and Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice,Nutrients,2018年,Vol. 10, No. 2 |
| The inhibition of malignant cell growth by ketone bodies,B. A. Magee, N. Potezny, A. M. Rofe, R. A. Conyers,Australian journal of experimental biology and medical science,1979年,57(5),529-39 |
Also Published As
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| PL3801490T3 (pl) | 2025-04-14 |
| EP3801490B1 (en) | 2024-12-04 |
| CA3102503A1 (en) | 2019-12-12 |
| GB201809113D0 (en) | 2018-07-18 |
| US12226387B2 (en) | 2025-02-18 |
| CN112384211A (zh) | 2021-02-19 |
| JP2021525775A (ja) | 2021-09-27 |
| DK3801490T3 (da) | 2025-03-03 |
| CN112384211B (zh) | 2025-01-03 |
| US20210212977A1 (en) | 2021-07-15 |
| ES3014285T3 (en) | 2025-04-21 |
| EP3801490A1 (en) | 2021-04-14 |
| GB2575623B (en) | 2022-10-26 |
| KR102863322B1 (ko) | 2025-09-22 |
| GB2575623A (en) | 2020-01-22 |
| WO2019234402A1 (en) | 2019-12-12 |
| KR20210019052A (ko) | 2021-02-19 |
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